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3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one

CAS No.
66521-54-8
Chemical Name:
3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one
Synonyms
5C-070;511676_ALDRICH;2-[3-(Dimethylamino)acryloyl]pyridine;3-(DIMETHYLAMINO)-1-(2-PYRIDYL)-2-PROPE&;3-(DIMETHYLAMINO)-1-(2-PYRIDYL)-2-PROPE&3-dimethylamino-1-(2-pyridyl)prop-2-en-1-one;1-(2-Pyridyl)-3-dimethylamino-2-propen-1-one;(E)-3-dimethylamino-1-(2-pyridyl)prop-2-en-1-one;3-(Dimethylamino)-1-(pyridin-2-yl)prop-2-en-1-one;3-(Dimethylamino)-1-(2-pyridyl)-2-propen-1-one 95%
CBNumber:
CB9499498
Molecular Formula:
C10H12N2O
Molecular Weight:
176.22
MDL Number:
MFCD00115039
MOL File:
66521-54-8.mol
MSDS File:
SDS
Last updated:2022-12-30 16:20:48

3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one Properties

Melting point 126-130 °C(lit.)
Boiling point 281.4±36.0 °C(Predicted)
Density 1.07
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 6.25±0.70(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  2933399990
NFPA 704
1
2 0

3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 511676 3-(Dimethylamino)-1-(2-pyridyl)-2-propen-1-one 95% 66521-54-8 25g $93 2023-06-20 Buy
TRC D495963 (E)-3-(Dimethylamino)-1-(pyridin-2-yl)prop-2-en-1-one 66521-54-8 5g $65 2021-12-16 Buy
Biosynth Carbosynth FD124317 (2E)-3-(Dimethylamino)-1-pyridin-2-ylprop-2-en-1-one 66521-54-8 500mg $75 2021-12-16 Buy
Biosynth Carbosynth FD124317 (2E)-3-(Dimethylamino)-1-pyridin-2-ylprop-2-en-1-one 66521-54-8 1g $128 2021-12-16 Buy
SynQuest Laboratories 4H32-1-27 3-(Dimethylamino)-1-(pyridin-2-yl)prop-2-en-1-one 98% 66521-54-8 25g $192 2021-12-16 Buy
Product number Packaging Price Buy
511676 25g $93 Buy
D495963 5g $65 Buy
FD124317 500mg $75 Buy
FD124317 1g $128 Buy
4H32-1-27 25g $192 Buy

3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one Chemical Properties,Uses,Production

Synthesis

3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one was synthesised based on the literature. The reaction of (2g, 16.5mmol) of 2-acetylpyridine and DMF dimethyl acetal(7.84g) were suspended in 11ml of xylene and stir this reaction mixture for 16h at 110℃. Into the resulting mixture 10 ml of hexane added yellow colour precipitate was formed and allows stirring for 20min at 3℃. Resulting mixture was filtered and dried in vacuum to get a yellow colour powder.1.png

Uses

3-(Dimethylamino)-1-(2-pyridyl)-2-propen-1-one may be used in the preparation of the 5-(heteroaryl)isoxazole derivatives, 5-(2-pyridyl)isoxazole and 3-methyl-5-(2-pyridyl)isoxazole. It may also be used to synthesize 7-(2-pyridyl)-1,2,4-triazolo[1,5-a]pyrimidine.

General Description

3-(Dimethylamino)-1-(2-pyridyl)-2-propen-1-one (1-(2′-Pyridyl)-3-dimethylamino-2-propen-1-one), an enaminone, is a hemilabile hybrid ligand. The preparation of cationic mononuclear rhodium(I) or iridium(I) complexes containing 3-(dimethylamino)-1-(2-pyridyl)-2-propen-1-one have been reported.

3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

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Capot Chemical Co.,Ltd.
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Acorn PharmaTech Co., Ltd. 025-58395930 sales@acornpharma.com China 982 60
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9900 58
3-(DIMETHYLAMINO)-1-(2-PYRIDYL)-2-PROPE& (E)-3-DiMethylaMino-1-(2-pyridyl)-2-propen-1-one, 98% 2-[3-(Dimethylamino)acryloyl]pyridine 3-(Dimethylamino)-1-(pyridin-2-yl)prop-2-en-1-one (E)-3-dimethylamino-1-(2-pyridyl)prop-2-en-1-one 3-(Dimethylamino)-1-(2-pyridyl)-2-propen-1-one 95% (2E)-3-(dimethylamino)-1-pyridin-2-ylprop-2-en-1-one 1-(2-Pyridyl)-3-dimethylamino-2-propen-1-one 3-dimethylamino-1-(2-pyridyl)prop-2-en-1-one 511676_ALDRICH 5C-070 InChI=1/C10H12N2O/c1-12(2)8-6-10(13)9-5-3-4-7-11-9/h3-8H,1-2H3/b8-6 2-Propen-1-one, 3-(dimethylamino)-1-(2-pyridinyl)- 3-(Dimethylamino)-1-(pyridin-2-yl)prop-2-en-1-one 98% JR-8942, 3-(Dimethylamino)-1-(2-pyridyl)-2-propen-1-one, 97% 3-(DIMETHYLAMINO)-1-(2-PYRIDYL)-2-PROPE& 3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one 66521-54-8 C9 to C46 Heterocyclic Building Blocks Pyridines