CITCO
- CAS No.
- Chemical Name:
- CITCO
- Synonyms
- CITCO;6-(4-CHLOROPHENYL)IMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE O-(3,4-DICHLOROBENZYL)OXIME
- CBNumber:
- CB9678165
- Molecular Formula:
- C19H12Cl3N3OS
- Molecular Weight:
- 436.74
- MDL Number:
- MFCD00139608
- MOL File:
- Mol file
Last updated:2023-04-23 13:52:06
Melting point | 142 - 144°C |
---|---|
storage temp. | −20°C |
solubility | DMSO: 28 mg/mL, soluble |
form | solid |
color | Off-White to Pale Beige |
FDA UNII | D77H8321PB |
CITCO Chemical Properties,Uses,Production
Uses
CITCO is a cell-permeable imidazothiazole compound that acts a CAR agonist.
Biological Activity
Constitutive androstane receptor (CAR) agonist (EC 50 = 49 nM). Displays > 100-fold selectivity over PXR receptors and no activity at LXR, ER α , ER β , PPAR, RAR, FXR, VDR and THR. Induces CAR nuclear translocation and expression of CYP2B6 in hepatocytes in vitro .
CITCO Preparation Products And Raw materials
Raw materials
Preparation Products
CITCO Suppliers
Global( 37)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
Supplier | Advantage |
---|---|
3B Pharmachem (Wuhan) International Co.,Ltd. | 69 |
(CITCO)Related Search:
CITCO
6-(4-CHLOROPHENYL)IMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE O-(3,4-DICHLOROBENZYL)OXIME