Monomethyl adipate
- CAS No.
- 627-91-8
- Chemical Name:
- Monomethyl adipate
- Synonyms
- 6-Methoxy-6-oxohexanoic acid;Adipic acid monometh;ADIPIC ACID MONOMETHYL ESTER;NSC55113;NSC 55113;NSC-55113;METHYL ADIPATE;Methyladipinate;Methyl hemiadipate;MONO-METHYL ADIPATE
- CBNumber:
- CB9683693
- Molecular Formula:
- C7H12O4
- Molecular Weight:
- 160.17
- MDL Number:
- MFCD00004418
- MOL File:
- 627-91-8.mol
- MSDS File:
- SDS
| Melting point | 7-9 °C (lit.) |
|---|---|
| Boiling point | 162 °C/10 mmHg (lit.) |
| Density | 1.081 g/mL at 25 °C (lit.) |
| vapor pressure | 1.48Pa at 25℃ |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| form | Liquid |
| pka | 4.69±0.10(Predicted) |
| color | Clear colorless |
| Water Solubility | Not miscible or difficult to mix with water. |
| BRN | 1766411 |
| LogP | 0.500 (est) |
| CAS DataBase Reference | 627-91-8(CAS DataBase Reference) |
| FDA UNII | 62S39VHD01 |
| NIST Chemistry Reference | Hexanedioic acid, monomethyl ester(627-91-8) |
| EPA Substance Registry System | Monomethyl adipate (627-91-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29171290 | |||||||||
| NFPA 704 |
|
Monomethyl adipate price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A26403 | mono-Methyl adipate 99% | 627-91-8 | 5g | $35.34 | 2024-03-01 | Buy |
| Sigma-Aldrich | A26403 | mono-Methyl adipate 99% | 627-91-8 | 25g | $101 | 2024-03-01 | Buy |
| TCI Chemical | A1738 | Monomethyl Adipate >97.0%(GC)(T) | 627-91-8 | 25g | $66 | 2024-03-01 | Buy |
| TCI Chemical | A1738 | Monomethyl Adipate >97.0%(GC)(T) | 627-91-8 | 100g | $201 | 2024-03-01 | Buy |
| Alfa Aesar | L09061 | Methyl hydrogen adipate, 99% | 627-91-8 | 25g | $87.9 | 2021-12-16 | Buy |
Monomethyl adipate Chemical Properties,Uses,Production
Chemical Properties
clear colorless liquid
Uses
Methyl hydrogen adipate is a useful synthetic intermediate. It can be used to prepare 1,3,4-thiadiazole hydroxamic acid derivatives as novel histone deacetylase inhibitors which show potential antitumor activities. It can be also used to synthesize mannose-linked biphenylylacetic acid derivatives as novel inhibitors of selectin-mediated cell adhesion.
Definition
ChEBI: Monomethyl adipate is a dicarboxylic acid monoester that is the monomethyl ester of adipic acid. It has a role as a metabolite and a plasticiser.
Synthesis
According to the general procedure described above, a has been synthesized from adipic acid (730mg, 5 mmol) and methanol (10 ml). Yield: 80%.
The synthetic method of Monomethyl adipate mainly contains following three kinds:
The one, under alkaline condition or issue the first portion hydrolysis reaction in the catalysis of bioactive enzyme (pork liver lipase etc.) and obtain Monomethyl adipate (such as document Blaise; Koehler; Bulletin de la Societe Chimique deFrance; Vol. (4) 7; (1910); P.219).
The 2nd, by hexanodioic acid or adipic anhydride and ethanol, as catalyzer, the control reaction conditions carries out esterification and obtains Monomethyl adipate (such as document Chem.Zentralbl. with acid; Vol.97; (1926; P.126));
The 3rd, by the people such as Swann nineteen forty-three with hexanodioic acid, diethylene adipate and ethanol with the condition of acid as catalyst under control reaction conditions obtain monomethyl adipate(document such as Swann; Oehler; Buswell; Org.synth.Coll.Vol.11; (1943); P.227).
Synthetic method of monomethyl adipate
http://www.orgsyn.org/demo.aspx?prep=CV2P0264
Monomethyl adipate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 | daisy@crovellbio.com | China | 5964 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
View Lastest Price from Monomethyl adipate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-11 | Monomethyl adipate
627-91-8
|
US $100.00-50.00 / KG | 1KG | 99% | 10000kg | Hebei Guanlang Biotechnology Co,.LTD | |
 |
2023-06-22 | Monomethyl adipate
627-91-8
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2022-10-18 | Monomethyl adipate
627-91-8
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- Monomethyl adipate
627-91-8
- US $100.00-50.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
-
- Monomethyl adipate
627-91-8
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- Monomethyl adipate
627-91-8
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.