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DYNAMIN INHIBITORY PEPTIDE

CAS No.
251634-21-6
Chemical Name:
DYNAMIN INHIBITORY PEPTIDE
Synonyms
P4;QVPSRPNRAP;Dynamin inhibitory p;DYNAMIN INHIBITORY PEPTIDE;L-Proline, L-glutaminyl-L-valyl-L-prolyl-L-seryl-L-arginyl-L-prolyl-L-asparaginyl-L-arginyl-L-alanyl-
CBNumber:
CB9687611
Molecular Formula:
C47H80N18O14
Molecular Weight:
1121.25
MDL Number:
MFCD06411592
MOL File:
251634-21-6.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59

DYNAMIN INHIBITORY PEPTIDE Properties

storage temp. Desiccate at -20°C
solubility ≥112.1 mg/mL in DMSO; ≥23.6 mg/mL in EtOH; ≥9.4 mg/mL in H2O
form solid
Water Solubility Soluble to 1 mg/ml in water

DYNAMIN INHIBITORY PEPTIDE price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 1774 Dynamininhibitorypeptide 251634-21-6 1 $292 2021-12-16 Buy
ApexBio Technology A1046 Dynamininhibitorypeptide 251634-21-6 5mg $360 2021-12-16 Buy
American Custom Chemicals Corporation PEP0004472 DYNAMIN INHIBITORY PEPTIDE 95.00% 251634-21-6 5MG $504.12 2021-12-16 Buy
ApexBio Technology A1046 Dynamininhibitorypeptide 251634-21-6 10mg $600 2021-12-16 Buy
ApexBio Technology A1046 Dynamininhibitorypeptide 251634-21-6 25mg $840 2021-12-16 Buy
Product number Packaging Price Buy
1774 1 $292 Buy
A1046 5mg $360 Buy
PEP0004472 5MG $504.12 Buy
A1046 10mg $600 Buy
A1046 25mg $840 Buy

DYNAMIN INHIBITORY PEPTIDE Chemical Properties,Uses,Production

Biological Activity

dynamin inhibitory peptide is a peptide (gln-val-pro-ser-arg-pro-asn-arg-ala-pro) inhibitor of the gtpase dynamin.dynamin is a 100-kda large gtpase that functions to tabulate membranes and liberate nascent vesicles from the golgi apparatus and plasma membrane. dynamin also plays a role in many processes including division of organelles,cytokinesis and microbial pathogen resistance.dynamin inhibitory peptide competitively blocks binding of dynamin to amphiphysin thus prevents endocytosis when administered intracellularly. reduces gabaa receptor internalization and increases miniature ispc amplitude and frequency in neurons expressing gabaa receptors.figure1 formula of dynamin inhibitory peptide

storage

Store at -20°C

References

1. McNiven, M. A., Cao, H., Pitts, K. R. & Yoon, Y. (2000) Trends Biochem. Sci. 25, 115–120.2. Hinshaw, J. E. (2000) Annu. Rev. Cell Dev. Biol 16, 483–519.3. Thoms S, Erdmann R (Oct 2005). "Dynamin-related proteins and Pex11 proteins in peroxisome division and proliferation.". FEBS J 272 (20): 5169–81.4. Grabs et al (1997) The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence. J.Biol.Chem. 272 13419-25.5. Kittler et al (2000) Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J.Neurosci. 20 7972-7. 6. Nong et al (2003) Glycine binding primes NMDA receptor internalization. Nature 422 302-7.

DYNAMIN INHIBITORY PEPTIDE Preparation Products And Raw materials

Raw materials

Preparation Products

DYNAMIN INHIBITORY PEPTIDE Suppliers

Global( 47)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd
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Aladdin Scientific
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AdooQ BioScience, LLC +1 (866) 930-6790 info@adooq.com United States 2784 58
ApexBio Technology LLC +1-832-696-8203 info@apexbt.com United States 477 60
Creative Peptides info@creative-peptides.com United States 6084 56
XinYao(Shenzhen) Biological Technology Co., Ltd. 0755-89880280 3004662104@qq.com China 1830 58

DYNAMIN INHIBITORY PEPTIDE Spectrum

DYNAMIN INHIBITORY PEPTIDE P4 L-Proline, L-glutaminyl-L-valyl-L-prolyl-L-seryl-L-arginyl-L-prolyl-L-asparaginyl-L-arginyl-L-alanyl- Dynamin inhibitory p QVPSRPNRAP 251634-21-6 C47H80N18O14 CancerBiology G-Protein