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Pentafluoro-1-propanol

CAS No.
422-05-9
Chemical Name:
Pentafluoro-1-propanol
Synonyms
2,2,3,3,3-PENTAFLUORO-1-PROPANOL;2,2,3,3,3-PENTAFLUOROPROPAN-1-OL;PFPOH;C2F5CH2OH;PENTAFLUOROPROPANOL;PENTAFLUORO-1-PROPANOL;1,1H-perfluoropropanol;Pentafluoropropylalcohol;PERFLUORODIHYDROPROPANOL;1H,1H-PENTAFLUOROPROPANOL
CBNumber:
CB9689963
Molecular Formula:
C3H3F5O
Molecular Weight:
150.05
MDL Number:
MFCD00004673
MOL File:
422-05-9.mol
MSDS File:
SDS
Last updated:2023-04-27 16:27:43

Pentafluoro-1-propanol Properties

Boiling point 80 °C748 mm Hg(lit.)
Density 1.505 g/mL at 25 °C(lit.)
vapor pressure 62.055-324.857hPa at 24.93-54.78℃
refractive index n20/D 1.288(lit.)
Flash point 80-81°C
storage temp. Flammables area
form Powder, Crystals and/or Chunks
pka 12.45±0.10(Predicted)
color White to off-white to light yellow
Specific Gravity 1.509
Water Solubility Soluble in water.21.9 g/L at 25°C
BRN 1743133
InChIKey PSQZJKGXDGNDFP-UHFFFAOYSA-N
LogP 1.23
CAS DataBase Reference 422-05-9(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII EPJ1S961SN
NIST Chemistry Reference 2,2,3,3,3-Pentafluoro-1-propanol(422-05-9)
EPA Substance Registry System 1-Propanol, 2,2,3,3,3-pentafluoro- (422-05-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280a-P304+P340-P405-P501a-P261-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38-20-10
Safety Statements  26-36-36/37/39-16
RIDADR  1987
WGK Germany  3
RTECS  UB8800000
TSCA  T
HazardClass  IRRITANT
HS Code  29055900
Toxicity LDLo orl-rat: 2250 mg/kg JOCMA7 4,262,62
NFPA 704
2
2 0

Pentafluoro-1-propanol price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 257478 2,2,3,3,3-Pentafluoro-1-propanol 97% 422-05-9 5g $41.7 2024-03-01 Buy
Sigma-Aldrich 257478 2,2,3,3,3-Pentafluoro-1-propanol 97% 422-05-9 25g $130 2024-03-01 Buy
TCI Chemical P0845 2,2,3,3,3-Pentafluoro-1-propanol >98.0%(GC) 422-05-9 25g $107 2024-03-01 Buy
Alfa Aesar A11846 2,2,3,3,3-Pentafluoro-1-propanol, 98% 422-05-9 5g $42.9 2023-06-20 Buy
Alfa Aesar A11846 2,2,3,3,3-Pentafluoro-1-propanol, 98% 422-05-9 25g $127 2023-06-20 Buy
Product number Packaging Price Buy
257478 5g $41.7 Buy
257478 25g $130 Buy
P0845 25g $107 Buy
A11846 5g $42.9 Buy
A11846 25g $127 Buy

Pentafluoro-1-propanol Chemical Properties,Uses,Production

Chemical Properties

clear colorless to slightly yellow liquid

Uses

2,2,3,3,3-Pentafluoro-1-propanol has been used:

  • as derivatization reagent in detection of unlabeled and 15N2 -labeled L-tryptophan, L-kynurenine, serotonin and quinolinic acid in human and rat plasma by GC-MS
  • as derivatization reagent in simultaneous analysis of cocaine, cocaethylene and their possible metabolic and pyrolytic products in blood, urine and muscle by GC-MS
  • preparation of trifluoromethyl ynamines which, in turn, converted aldehydes to α-trifluoromethyl-α,β-unsaturated amides
  • to generate fluorinated α-keto ethers with alkenes and has wide applications in the expanding fluorous research area

Uses

2,2,3,3,3-Pentafluoro-1-Propanol is a useful reagent for the preparation of (oxoindolinyl)ethers/benzoates via photochemical O-H functionalization reactions of cyclic diazoamides.

General Description

2,2,3,3,3-Pentafluoro-1-propanol is an alternative cleaning agent for chlorofluorocarbon.

Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of Fí.

Purification Methods

Shake the alcohol with alumina for 24hours, dry with anhydrous K2CO3, and distil it, collect the middle fraction (b 80-81o) and redistil it. [Beilstein 1 IV 1438.]

422-64-0
422-05-9
Synthesis of Pentafluoro-1-propanol from Perfluoropropionic acid
Global( 228)Suppliers
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career henan chemical co
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View Lastest Price from Pentafluoro-1-propanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pentafluoro-1-propanol pictures 2022-09-16 Pentafluoro-1-propanol
422-05-9
US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
2,2,3,3,3-Pentafluoro-1-Propanol pictures 2019-07-06 2,2,3,3,3-Pentafluoro-1-Propanol
422-05-9
US $250.00 / KG 2KG 98% 500kg per month Career Henan Chemical Co
2,2,3,3,3-Pentafluoropropanol-1 1H,1H-PENTAFLUOROPROPANOL 97% 2,2,3,3,3-Pentafluoropropan-1-ol 98% 2,2,3,3,3-Pentafluoropropan-1-ol98% 2,2,3,3,3-Pentafluoropropanol (PFP) 2,2,3,3,3-PENTAFLUORO-L-PROPANOL 2,2,3,3,3-PENTAFLUOROPROPANOL 2,2,3,3,3-Pentafluoro-1-propanol, 95+% Pentafluoropropylalcohol 2,2,3,3,3-Pentafluoro-1-propanol,97% 1H,1H-Pentafluoropropan-1-ol 3-Hydroxy-1,1,1,2,2-pentafluoropropane, 1H,1H-Pentafluoropropan-1-ol PENTAFLUOROPROPANOL PERFLUORODIHYDROPROPANOL PENTAFLUORO-1-PROPANOL 1,1-Dihydroperfluoropropanol 1,1H-perfluoropropanol 1-Propanol, 2,2,3,3,3-pentafluoro- 2,2,3,3,3-pentafluoro-1-propano C2F5CH2OH propanol,2,2,3,3,3-pentafluoro- Pentafluoropropionic alcohol 1H,1H-PENTAFLUORO-1-PROPANOL 1H,1H-PENTAFLUOROPROPANOL 1H,1H-PENTAFLUOROPROPANOL-1 2,2,3,3,3-Pentafluoro-1-propanol> 2,2,3,3,3-PENTAFLUORO-1-PROPANOL 2,2,3,3,3-PENTAFLUOROPROPAN-1-OL PFPOH 422-05-9 CF3CF2CH2OH C3H3OF5 Organic Building Blocks Oxygen Compounds C2 to C6 Building Blocks Alkylation Alcohols ALCOHOL Acylation Reagent