ChemicalBook >> CAS DataBase List >>9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER structure

CAS No.: 309260-52-4

Chemical Name:: 9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER

Synonyms: PGD2-1-GLYCERYL ESTER;PROSTAGLANDIN D2-1-GLYCERYL ESTER;9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER;Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (5Z,9α,13E,15S)-

CBNumber:: CB9691036

Molecular Formula:: C23H38O7

Molecular Weight:: 426.54

MDL Number:: MFCD05863733

MOL File:: 309260-52-4.mol

Last updated:2025-04-17 18:22:24

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9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER Properties

solubility	DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): .1 mg/ml

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	12015	Prostaglandin D2-1-glyceryl ester ≥95% (as a 9:1 mixture of the 1- and 2-glyceryl esters)	309260-52-4	500μg	$62	2024-03-01	Buy
Cayman Chemical	12015	Prostaglandin D2-1-glyceryl ester ≥95% (as a 9:1 mixture of the 1- and 2-glyceryl esters)	309260-52-4	1mg	$104	2024-03-01	Buy
Cayman Chemical	12015	Prostaglandin D2-1-glyceryl ester ≥95% (as a 9:1 mixture of the 1- and 2-glyceryl esters)	309260-52-4	5mg	$448	2024-03-01	Buy
Cayman Chemical	12015	Prostaglandin D2-1-glyceryl ester ≥95% (as a 9:1 mixture of the 1- and 2-glyceryl esters)	309260-52-4	10mg	$576	2021-12-16	Buy
AK Scientific	1561AH	9alpha,15S-Dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oicacid,1-glycerylester	309260-52-4	5mg	$537	2021-12-16	Buy

Product number	Packaging	Price	Buy
12015	500μg	$62	Buy
12015	1mg	$104	Buy
12015	5mg	$448	Buy
12015	10mg	$576	Buy
1561AH	5mg	$537	Buy

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER Chemical Properties,Uses,Production

Description

2-Arachidonoyl glycerol (2-AG; ) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB₁ receptor.^1,2 Incubation of 2-AG with COX-2 and specific prostaglandin H₂ (PGH₂; ) isomerases in cell cultures and isolated enzyme preparations results in prostaglandin glycerol ester formation.³ The biosynthesis of PGH, PGD, PGE, PGF, and TXA-2-glyceryl ester compounds have all been documented. In RAW 264.7 cells, PGD₂-2-glyceryl ester is the main COX metabolite.³ The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 mixture of the 1- and 2-glyceryl esters in typical aqueous media. While the stability and metabolism of these PG products have been investigated, little is known about their intrinsic biological activity.⁴

Uses

Prostaglandin D2-1-glyceryl ester (PGD2-G; PGD2 2-glyceryl ester)[1].

Definition

ChEBI: Prostaglandin D2 1-glyceryl ester is a 1-monoglyceride resulting from the condensation of the carboxy group of prostaglandin D2 with the 1-hydroxy group of glycerol. It has a role as a human metabolite. It is a prostaglandins D, an alicyclic ketone, a 1-monoglyceride and a secondary allylic alcohol. It is functionally related to a prostaglandin D2.

References

1. Sugiura, T., Kodaka, T., Kondo, S., et al. 2-Arachidonoylglycerol, a putative endogenous cannabinoid receptor ligand, induces rapid, transient elevation of intracellular free Ca²⁺ in neuroblastoma X glioma hybrid NG108-15 cells Biochem. Biophys. Res. Commun. 229,58-64(1996).
2. Sugiura, T., Kodaka, T., Kondo, S., et al. Is the cannabinoid CB₁ receptor a 2-arachidonoylglycerol receptor? Structural requirements for triggering a Ca²⁺ transient in NG108-15 cells J. Biochem. 122(4),890-895(1997).
3. Kozak, K.R., Crews, B.C., Morrow, J.D., et al. Metabolism of the endocannabinoids, 2-arachidonylgycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides J. Biol. Chem. 277(47),44877-44885(2002).
4. Kozak, K.R., Crews, B.C., Ray, J.L., et al. Metabolism of prostaglandin glycerol esters and prostaglandin ethanolamides in vitro and in vivo J. Biol. Chem. 276(40),36993-36998(2001).

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER Suppliers

Global( 16)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd	0571-85361029	synstar518@163.com	China	1990	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11973	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	19930	58
Chengdu Peter-like Biotechnology Co., Ltd.	028-81700200 13308200041	2851167782@qq.com	China	11183	58
Cayman Chemical Company	800-364-9897	sales@caymanchem.com	China	27736	58
Santa Cruz Biotechnology Inc	60936350	scbt@scbt.com	China	222068	58

Supplier	Advantage
Shanghai Hongye Biotechnology Co. Ltd	58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd	58
Shanghai Yifei Biotechnology Co. , Ltd.	58
TargetMol Chemicals Inc.	58
Chengdu Peter-like Biotechnology Co., Ltd.	58
Cayman Chemical Company	58
Santa Cruz Biotechnology Inc	58

309260-52-4(9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER)Related Search:

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER PROSTAGLANDIN D2

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER PGD2-1-GLYCERYL ESTER PROSTAGLANDIN D2-1-GLYCERYL ESTER Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (5Z,9α,13E,15S)- 309260-52-4