ChemicalBook >> CAS DataBase List >>GYKI 52466 HYDROCHLORIDE
GYKI 52466 HYDROCHLORIDE
- CAS No.
- 102771-26-6
- Chemical Name:
- GYKI 52466 HYDROCHLORIDE
- Synonyms
- 466;2466;CS-813;GYKI-5;GYKI52;GYKI 52;Gyki Hcl;gyki52466;GYKI52466HCl;Gyki Hydrochloride
- CBNumber:
- CB9701780
- Molecular Formula:
- C17H16ClN3O2
- Molecular Weight:
- 329.78
- MDL Number:
- MFCD00885518
- MOL File:
- 102771-26-6.mol
Last updated:2023-06-30 15:45:59
| Boiling point | 472.8±45.0 °C(Predicted) |
|---|---|
| Density | 1.39 |
| storage temp. | Desiccate at RT |
| solubility | DMSO: 0.39 mg/mL |
| pka | 8.14±0.20(Predicted) |
| form | solid |
| color | yellow |
| EWG's Food Scores | 1 |
| FDA UNII | 471V8NZ5X3 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H319-H315 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-26-36 |
| WGK Germany | 3 |
GYKI 52466 HYDROCHLORIDE price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 1454 | GYKI52466dihydrochloride ≥98%(HPLC) | 102771-26-6 | 50 | $670 | 2021-12-16 | Buy |
| Tocris | 1454 | GYKI52466dihydrochloride ≥98%(HPLC) | 102771-26-6 | 10 | $162 | 2021-12-16 | Buy |
| Usbiological | 255423 | GYKI 52466 dihydrochloride | 102771-26-6 | 10mg | $403 | 2021-12-16 | Buy |
| TRC | M303695 | 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine | 102771-26-6 | 50mg | $545 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 47448 | 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine | 102771-26-6 | 10mg | $620 | 2021-12-16 | Buy |
GYKI 52466 HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine is a non-competitive AMPA receptor antagonist and was found to have therapeutic potential for cocaine addiction treatment.
Definition
ChEBI: GYKI 52466 is a benzodiazepine.
Biological Activity
Selective non-competitive AMPA receptor antagonist (IC 50 values are 10-20, ~ 450 and >> 50 μ M for AMPA- , kainate- and NMDA-induced responses respectively). Skeletal muscle relaxant and orally-active anticonvulsant. Has anti-proliferative effects in transformed cells. Also available as part of the AMPA Receptor Tocriset™ . Also available as part of the Kainate Receptor Tocriset™ .
storage
room temperature (desiccate)
GYKI 52466 HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
GYKI 52466 HYDROCHLORIDE Suppliers
Global( 73)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2127 | 70 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2784 | 58 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9798 | 50 |
102771-26-6(GYKI 52466 HYDROCHLORIDE)Related Search:
gyki52466
4-(8-METHYL-9H-1,3-DIOXOLO[4,5-H][2,3]BENZODIAZEPIN-5-YL)-BENZENAMINE HYDROCHLORIDE
GYKI 52466 HYDROCHLORIDE
4-(8-Methyl-(9H)-1,3-dioxolo[4.5-h][2.3]benzodiazepine-5-yl)benzenaminehydrochloride
GYKI52466HCl
1-(4-Aminophenyl)-4-methyl-7,8-(methylenedioxy)-5H-2,3-benzodiazepine
4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-5-yl)aniline
1-(p-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride
4-(8-Methyl-9H-1,3-dioxolo(4,5-H)(2,3)benzodiazepin-5-yl)benzenamine
Benzenamine, 4-(8-methyl-9H-1,3-dioxolo(4,5-H)(2,3)benzodiazepin-5-yl)-
Gyki Hcl
4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-benzenaminedihydrochloride
GYKI 52466 dihydrochloride
Gyki Hydrochloride
4-(8-methyl-8,9-dihydro-7H-[1,3]dioxolo[4,,5,:4,5]benzo[1,2-d][1,2]diazepin-5-yl)aniline
GYKI52466;GYKI-52466
CS-813
2466
466
GYKI 52
GYKI-5
GYKI52
102771-26-6
C17H15N3O22HCl
C17H15N3O2HCl
Cell Signaling and Neuroscience
Cell Biology
BioChemical
Ionotropic Glutamate Receptor Modulators
Ion Channels
Ligand-Gated Ion Channels
Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals