TDZD-8

TDZD-8 structure

CAS No.

Chemical Name:: TDZD-8

Synonyms: TDZD-8;GSK-3BETA INHIBITOR I;4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE

CBNumber:: CB9702181

Molecular Formula:: C10H10N2O2S

Molecular Weight:: 222.26

MDL Number:: MFCD04973552

MOL File:: Mol file

Last updated:2023-04-23 13:52:06

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TDZD-8 Properties

Melting point	63-64.4 °C
storage temp.	2-8°C
solubility	DMSO: 18 mg/mL
form	needles
color	white

SAFETY

Risk and Safety Statements

Hazard Codes	Xi
Risk Statements	43
Safety Statements	36/37
WGK Germany	3

TDZD-8 price More Price(4)

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Alfa Aesar	J64048	GSK-3beta Inhibitor I	5mg	$108	2021-12-16	Buy
Usbiological	B1078-01E	4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione	10mg	$333	2021-12-16	Buy
Biorbyt Ltd	orb146107	TDZD-8 >98%	100mg	$615.4	2021-12-16	Buy
Biorbyt Ltd	orb146107	TDZD-8 >98%	1g	$1949.9	2021-12-16	Buy

Product number	Packaging	Price	Buy
J64048	5mg	$108	Buy
B1078-01E	10mg	$333	Buy
orb146107	100mg	$615.4	Buy
orb146107	1g	$1949.9	Buy

TDZD-8 Chemical Properties,Uses,Production

Uses

A thiadiazolidinone (TDZD) analog that acts as a highly selective, non-ATP competitive inhibitor of GSK-3

Uses

Glycogen Synthase Kinase-3? is a highly conserved ubiquitously expressed serine/threonine protein kinase involved in signal transduction cascades of multiple cellular processes. TDZD-8 is a thiadiazolidinone (TDZD) analogue that acts as a highly selective, non-ATP competitive inhibitor of GSK-3? ( IC50 =2nM). Binds to the active site of GSK-3?. Does not significantly affect the activities of Cdk-1/cyclin B, CK-II, PKA, and PKC (IC50 >100nM).

TDZD-8 Preparation Products And Raw materials

Raw materials

Preparation Products

TDZD-8 Suppliers

Global( 84)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2923	55
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
GIHI CHEMICALS CO.,LTD	0086-571-86217390	Sales@gihichem.com	China	861	58
Tianjin Anhao Biological Technology Co., Ltd.		sales@ahpharmatech.com	China	5738	55
Credit Asia Chemical Co., Ltd.	+86 (21) 61124340		China	9767	58
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	3444	55
Chuzhou KeMail Chemical Technology Co., Ltd	0550-5196001 15000891977	wj520wjxby@126.com	China	1831	55

Supplier	Advantage
career henan chemical co	58
Zhejiang J&C Biological Technology Co.,Limited	58
Amadis Chemical Company Limited	58
Shanghai Boyle Chemical Co., Ltd.	55
3B Pharmachem (Wuhan) International Co.,Ltd.	69
GIHI CHEMICALS CO.,LTD	58
Tianjin Anhao Biological Technology Co., Ltd.	55
Credit Asia Chemical Co., Ltd.	58
Tianjin Kailiqi Biotechnology Co., Ltd.	55
Chuzhou KeMail Chemical Technology Co., Ltd	55

View Lastest Price from TDZD-8 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-12-24	TDZD-8 7036-89-5	US $1.00 / g	1g	99%	20kg	Career Henan Chemical Co

TDZD-8
7036-89-5
US $1.00 / g
99%
Career Henan Chemical Co

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4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE GSK-3BETA INHIBITOR I TDZD-8 7036-89-5