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ChemicalBook >> CAS DataBase List >>3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE

3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE

3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE Structure
3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE structure
CAS No.
691410-93-2
Chemical Name:
3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE
Synonyms
AN-7;AN7,AN 7;α-lipoic acid derivatives;3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE;1,2-Dithiolane-3-pentanamide, N,N'-1,3-propanediylbis-;5-(dithiolan-3-yl)-N-[3-[5-(dithiolan-3-yl)pentanoylamino]propyl]pentanamide
CBNumber:
CB9712795
Molecular Formula:
C19H34N2O2S4
Molecular Weight:
450.75
MDL Number:
MFCD23380216
MOL File:
Mol file
Last updated:2023-05-21 10:59:17
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3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE Properties

Melting point 79-81 °C
Boiling point 702.1±43.0 °C(Predicted)
Density 1.178±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 10 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2)(1:4): .15 mg/ml; Ethanol: 2 mg/ml
form A crystalline solid
pka 15.86±0.46(Predicted)

3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10006212 AN-7 ≥98% 691410-93-2 1mg $32 2024-03-01 Buy
Cayman Chemical 10006212 AN-7 ≥98% 691410-93-2 5mg $100 2024-03-01 Buy
Cayman Chemical 10006212 AN-7 ≥98% 691410-93-2 10mg $184 2024-03-01 Buy
AK Scientific 7508CR 5-(Dithiolan-3-yl)-N-[3-[5-(dithiolan-3-yl)pentanoylamino]propyl]pentanamide 691410-93-2 1mg $133 2021-12-16 Buy
Product number Packaging Price Buy
10006212 1mg $32 Buy
10006212 5mg $100 Buy
10006212 10mg $184 Buy
7508CR 1mg $133 Buy

3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE Chemical Properties,Uses,Production

Description

α-Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle and acts as a general antioxidant.1 AN-7 is a more lipophilic analog of α-lipoic acid with enhanced potency and 1.5-fold increased maximal capacity to stimulate glucose transport into myocytes.2 This identifies the analogs of lipoic acid as potential new treatments for diabetes.

References

1. Biewenga, G.P., Haenen, G.R.M.M., and Bast, A. The pharmacology of the antioxidant lipoic acid Gen. Pharmacol. 29(3),315-331(1997).
2. Gruzman, A., Hidmi, A., Katzhendler, J., et al. Synthesis and characterization of new and potent α-lipoic acid derivatives Bioorg. Med. Chem. 12,1183-1190(2004).

3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE Suppliers

Global( 22)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-400-8210725 4008210725 malulu@leyan.com China 55023 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58
MedBioPharmaceutical Technology Inc 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
AN-7 3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE 5-(dithiolan-3-yl)-N-[3-[5-(dithiolan-3-yl)pentanoylamino]propyl]pentanamide α-lipoic acid derivatives AN7,AN 7 1,2-Dithiolane-3-pentanamide, N,N'-1,3-propanediylbis- 691410-93-2