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(S)-1-N-Boc-2-methylpiperazine

(S)-1-N-Boc-2-methylpiperazine structure

CAS No.: 169447-70-5

Chemical Name:: (S)-1-N-Boc-2-methylpiperazine

Synonyms: tert-butyl (S)-2-methylpiperazine-1-carboxylate;(R)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-1-Boc-2-methl-piperazine;(S)-N-Boc-2-methylpiperazine;(R)-2-METHYL-1-BOC-PIPERAZINE;(S)-1-Boc-2-methyl-piperazine;(S)-N1-BOC-2-METHYLPIPERAZINE;1-Boc-2-(S)-Methyl Piperazine;(S)-1-N-BOC-2-METHYL PIPERAZINE

CBNumber:: CB9714476

Molecular Formula:: C10H20N2O2

Molecular Weight:: 200.28

MDL Number:: MFCD01862121

MOL File:: 169447-70-5.mol

Last updated:2023-12-18 16:59:08

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(S)-1-N-Boc-2-methylpiperazine Properties

Melting point	43.0 to 47.0 °C
Boiling point	268.7±15.0 °C(Predicted)
Density	0.997±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble in Methanol
form	powder to crystal
pka	8.49±0.40(Predicted)
color	White to Almost white
InChI	InChI=1S/C10H20N2O2/c1-8-7-11-5-6-12(8)9(13)14-10(2,3)4/h8,11H,5-7H2,1-4H3/t8-/m0/s1
InChIKey	DATRVIMZZZVHMP-QMMMGPOBSA-N
SMILES	N1(C(OC(C)(C)C)=O)CCNC[C@@H]1C
CAS DataBase Reference	169447-70-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS05
Signal word	Danger
Hazard statements	H314
Precautionary statements	P260-P271
RIDADR	UN3077
HS Code	2933599590

(S)-1-N-Boc-2-methylpiperazine price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B4846	(S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine >98.0%(GC)(T)	169447-70-5	1g	$65	2024-03-01	Buy
TCI Chemical	B4846	(S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine >98.0%(GC)(T)	169447-70-5	5g	$258	2024-03-01	Buy
TRC	B656975	(S)-1-Boc-2-methylpiperazine	169447-70-5	10g	$970	2021-12-16	Buy
Activate Scientific	AS3110	(S)-1-Boc-2-methylpiperazine 97+% ee	169447-70-5	250g	$1480	2021-12-16	Buy
American Custom Chemicals Corporation	CCH0040694	(S)-1-N-BOC-2-METHYLPIPERAZINE 95.00%	169447-70-5	10G	$2055.9	2021-12-16	Buy

Product number	Packaging	Price	Buy
B4846	1g	$65	Buy
B4846	5g	$258	Buy
B656975	10g	$970	Buy
AS3110	250g	$1480	Buy
CCH0040694	10G	$2055.9	Buy

(S)-1-N-Boc-2-methylpiperazine Chemical Properties,Uses,Production

Uses

(S)-1-N-Boc-2-methylpiperazine is used in the preparation of pyrazolo[3,4-b]pyridine dual pharmacophores as PDE4-muscarinic antagonists.

Synthesis

A solution of (S)-2-methyl piperazine (2 g, 20 mmol) in THF (200 ml_) was mixed with nBuLi (25 ml, 1.6 M in hexanes, 40 mmol) at rt. The solution was stirred for 30 minutes before TBDMSCI (3.04 g, 20 mmol) was added. The mixture was stirred for 1 hour and then (Boc)2O (5.2 g, 24 mmol) was added to the solution. After 1 hour, the solution was diluted with H2O (50 ml). The organic layer was separated, washed with brine (50 mL), dried over Na2SO4, and concentrated EPO under vacuum. Finally, (S)-1-N-Boc-2-methylpiperazine was obtained after purification.

(S)-1-N-Boc-2-methylpiperazine synthesis

Synthesis of (S)-1-N-Boc-2-methylpiperazine from Di-tert-butyl dicarbonate

(S)-1-N-Boc-2-methylpiperazine Preparation Products And Raw materials

Raw materials

(S)-1-BENZYL-3-METHYLPIPERAZINE-2,5-DIONE (S)-TERT-BUTYL 4-BENZYL-2-METHYLPIPERAZINE-1-CARBOXYLATE (S)-METHYL 2-(2-CHLOROACETAMIDO) PROPANOATE 2-(S)-METHYLPIPERAZINE-1,4-DICARBOXYLIC ACID 4-BENZYL ESTER 1-TER-BUTYL ESTER (S)-(+)-2-Methylpiperazine

(S)-2-METHYL-4-BENZYLPIPERAZINE

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Preparation Products

FVQORRADVAYZAV-AWEZNQCLSA-N

(S)-1-N-Boc-2-methylpiperazine Suppliers

Global( 254)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Boc Chemical Co., Ltd.	021-34975602; +8618721111801	shangli@bocchem.com	China	138	58
Purest Pharmaceuticl （Xi’an) Co,.LTD	+8613893405577	12829054@qq.com	China	74	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	6711	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Chembon Pharmaceutical Co., Ltd.	+86-28-8425-2981		CHINA	724	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	6992	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58

Supplier	Advantage
Shanghai Boc Chemical Co., Ltd.	58
Purest Pharmaceuticl （Xi’an) Co,.LTD	58
Shanghai UCHEM Inc.	58
Capot Chemical Co.,Ltd.	60
Chembon Pharmaceutical Co., Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Jinan Carbotang Biotech Co.,Ltd.	58
Accela ChemBio Inc.	58

View Lastest Price from (S)-1-N-Boc-2-methylpiperazine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-02-23	(S)-1-N-Boc-2-methylpiperazine 169447-70-5	US $73.00-607.00 / g	25g	0.99	10	Shanghai UCHEM Inc.
	2019-08-09	(S)-1-N-Boc-2-methylpiperazine 169447-70-5	US $8.80 / KG	1KG	97%-99%	100kg	Career Henan Chemical Co

(S)-1-N-Boc-2-methylpiperazine
169447-70-5
US $73.00-607.00 / g
0.99
Shanghai UCHEM Inc.

(S)-1-N-Boc-2-methylpiperazine
169447-70-5
US $8.80 / KG
97%-99%
Career Henan Chemical Co

(S)-1-N-Boc-2-methylpiperazine Spectrum

(S)-1-N-Boc-2-methylpiperazine(169447-70-5)¹HNMR

169447-70-5((S)-1-N-Boc-2-methylpiperazine)Related Search:

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D-1-N-Boc-prolinamide (S)-(+)-N-TBOC-2-METHYLPIPERIDINE (S)-tert-butyl 4-aMinoazepane-1-carboxylate

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(R)-2-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (R)-2-METHYL-1-BOC-PIPERAZINE (S)-1-N-BOC-2-METHYL PIPERAZINE (S)-2-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (S)-1-Boc-2-methyl-piperazine Tert-Butyl2(S)-methylpiperazine-1-carboxylate 2-S-Methyl-piperazine-1-carboxylic acid tert-butyl ester (S)-1-N-Boc-2-Methylpiperizine tert-butyl 2(S)-methylpiperazine-1-carboxylate (S)-N1-BOC-2-METHYLPIPERAZINE (S)-1-Boc-2-methl-piperazine (S)-1-N-Boc-2-Methylpiperazine ,98% (2S)-2-Methylpiperazine, N1-BOC protected 98% tert-Butyl (2S)-2-methylpiperazine-1-carboxylate (2S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine (2S)-2-Methyl-1-piperazinecarboxylic Acid 1,1-DiMethylethyl Ester tert-Butyl (2S)-2-Methylpiperazine-1-carboxylate 1-Piperazinecarboxylic acid, 2-methyl-, 1,1-dimethylethyl ester, (2S)- (S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine (2S)-2-Methylpiperazine,N1-BOCprotected98% (S)-N-Boc-2-methylpiperazine (S)-N-Boc-2-methylpiperazine,98%e.e. (S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine 1-Boc-2-(S)-Methyl Piperazine TERT-BUTYL (2S)-2-METHYPIPERAZINE-1-CARBOXYLATE (S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine > tert-Butyl (S)-2-Methyl-1-piperazinecarboxylate (S)-2-Methyl-1-piperazinecarboxylic Acid tert-Butyl Ester (S)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE (R)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE tert-butyl (S)-2-methylpiperazine-1-carboxylate 169447-70-5 170033-47-4 Chiral Reagents Heterocycles pharmacetical Piperaizine