4'-(Trifluoromethyl)acetophenone
- CAS No.
- 709-63-7
- Chemical Name:
- 4'-(Trifluoromethyl)acetophenone
- Synonyms
- 4-(TRIFLUOROMETHYL)ACETOPHENONE;1-(4-Trifluoromethyl-phenyl)-ethanone;NSC 88346;4-Acetylbe;4-ACETYLBENZOFLUORIDE;On the trifluoroMethyl;4-ACETYLBENZOTRIFLUORIDE;P-TRIFLUOROMETHYLACETOPHENONE;4-(trifluromethyl)acetophenone;4-TRIFLUOROMETHYL BENZYLDEHYDE
- CBNumber:
- CB9717518
- Molecular Formula:
- C9H7F3O
- Molecular Weight:
- 188.15
- MDL Number:
- MFCD00000401
- MOL File:
- 709-63-7.mol
- MSDS File:
- SDS
Melting point | 30-33 °C(lit.) |
---|---|
Boiling point | 79-80 °C8 mm Hg(lit.) |
Density | 0.92 |
refractive index | 1.4604 |
Flash point | 184 °F |
storage temp. | Sealed in dry,Room Temperature |
form | Low Melting Solid |
color | White to faintly yellow |
BRN | 1870425 |
CAS DataBase Reference | 709-63-7(CAS DataBase Reference) |
FDA UNII | TZ2PGR8637 |
NIST Chemistry Reference | 4-CF3-C6H4-COCH3(709-63-7) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319 | |||||||||
Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 | |||||||||
Hazard Codes | Xi,F | |||||||||
Risk Statements | 36/37/38-11 | |||||||||
Safety Statements | 26-36-37/39-16 | |||||||||
WGK Germany | 3 | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29147090 | |||||||||
NFPA 704 |
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4'-(Trifluoromethyl)acetophenone price More Price(37)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 233188 | 4′-(Trifluoromethyl)acetophenone 98% | 709-63-7 | 25g | $112.2 | 2024-03-01 | Buy |
Sigma-Aldrich | 233188 | 4′-(Trifluoromethyl)acetophenone 98% | 709-63-7 | 5g | $120 | 2024-03-01 | Buy |
TCI Chemical | T1784 | 4'-(Trifluoromethyl)acetophenone >98.0%(GC) | 709-63-7 | 1g | $16 | 2024-03-01 | Buy |
TCI Chemical | T1784 | 4'-(Trifluoromethyl)acetophenone >98.0%(GC) | 709-63-7 | 5g | $41 | 2024-03-01 | Buy |
Alfa Aesar | A15529 | 4'-(Trifluoromethyl)acetophenone, 98+% | 709-63-7 | 5g | $93.65 | 2024-03-01 | Buy |
4'-(Trifluoromethyl)acetophenone Chemical Properties,Uses,Production
Synthesis
41.6 g of chlorocyclohexane (0.35 mol) were added dropwise to a suspension of 4.65 g of lithium particles (0.68 mol) in 350 g of THF at -55 °C, and an addition time of 2 hours was chosen. After >97% chlorocyclohexane conversion by GC (10 hours), a mixture of 38.3 g of 4-bromotrifluorotoluene (0.170 mol) and 7.0 g of acetonitrile (0.170 mol) was added dropwise at the same temperature for 15 minutes. After stirring for an additional 30 minutes at -50°C, the reaction mixture was slowly thawed to room temperature and subjected to an aqueous workup in a conventional manner. The yield of 4-trifluoromethylacetophenone after distillation was 81%.
Chemical Properties
White to faintly yellow low melting solid
Uses
A labelled acetophenone with selective antimycobacterial activity.
General Description
The enantioselective addition of dialkylzinc to 4′-(trifluoromethyl)acetophenone mediated by 1,2-bis(hydroxycamphorsulfonamido)cyclohexenes in the presence of titanium tetraisopropoxide has been investigated. Phosphorescence emission spectra of 4′-(trifluoromethyl)acetophenone has been studied using pulsed source phosphorimetry.
Purification Methods
Purify the ketone by distillation or sublimation in vacuo.[Beilstein 7 IV 1404.]
4'-(Trifluoromethyl)acetophenone Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18632 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21667 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2136 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 7621 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10828 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
View Lastest Price from 4'-(Trifluoromethyl)acetophenone manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2022-01-04 | 4-(Trifluoromethyl)acetophenone
709-63-7
|
US $0.00-0.00 / KG | 1g | 98%min | 100kgs/month | Shanghai Rlavie Technology Co ltd | ||
2021-11-15 | 4'-(TrifluoroMet
709-63-7
|
US $10.80 / KG | 1KG | 99% | 500ton/Month | Qiuxian Baitai New Material Co., LTD | ||
2021-07-20 | 4'-(Trifluoromethyl)acetophenone
709-63-7
|
US $0.00-0.00 / KG | 10mg | 99% | 2000tons | Shaanxi Dideu Medichem Co. Ltd |
- 4-(Trifluoromethyl)acetophenone
709-63-7
- US $0.00-0.00 / KG
- 98%min
- Shanghai Rlavie Technology Co ltd
- 4'-(TrifluoroMet
709-63-7
- US $10.80 / KG
- 99%
- Qiuxian Baitai New Material Co., LTD
- 4'-(Trifluoromethyl)acetophenone
709-63-7
- US $0.00-0.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd