4-Amino-3-methylbenzoic acid
- CAS No.
- 2486-70-6
- Chemical Name:
- 4-Amino-3-methylbenzoic acid
- Synonyms
- 3-METHYL-4-AMINOBENZOIC ACID;Fluralaner-034;RARECHEM AL BO 2396;4-Amino-3-methylbenz;4-AMINO-M-TOLUIC ACID;4-Amino-n-toluic acid;3-Methyl-4-AMino acid;Carbidopa Impurity 24;Fluralaner Impurity 54;4-Amino-3-methylbenzoic
- CBNumber:
- CB9724176
- Molecular Formula:
- C8H9NO2
- Molecular Weight:
- 151.16
- MDL Number:
- MFCD00007736
- MOL File:
- 2486-70-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Amino-3-methylbenzoic acid 98% | A63007 | 1g | $46.6 |
| 4-Amino-3-methylbenzoic acid 98% | A63007 | 10g | $426 |
| 4-Amino-3-methylbenzoic Acid >98.0%(HPLC)(T) | A1353 | 5g | $56 |
| 4-Amino-3-methylbenzoic Acid >98.0%(HPLC)(T) | A1353 | 25g | $167 |
| 4-Amino-3-methylbenzoic Acid | A614585 | 10g | $60 |
| More product size | |||
| Melting point | 169-171 °C (lit.) |
|---|---|
| Boiling point | 273.17°C (rough estimate) |
| Density | 1.2023 (rough estimate) |
| refractive index | 1.5810 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 4.93±0.10(Predicted) |
| color | Pale Brown to Light Brown |
| BRN | 2802615 |
| Stability | Light Sensitive |
| InChI | InChI=1S/C8H9NO2/c1-5-4-6(8(10)11)2-3-7(5)9/h2-4H,9H2,1H3,(H,10,11) |
| InChIKey | NHFKECPTBZZFBC-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=C(N)C(C)=C1 |
| CAS DataBase Reference | 2486-70-6(CAS DataBase Reference) |
| FDA UNII | 201CXT4H5V |
| NIST Chemistry Reference | 4-Amino-3-methylbenzoic acid(2486-70-6) |
| UNSPSC Code | 12352200 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P305+P351+P338-P280a-P304+P340-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29224999 | |||||||||
| NFPA 704 |
|
4-Amino-3-methylbenzoic acid price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A63007 | 4-Amino-3-methylbenzoic acid 98% | 2486-70-6 | 1g | $46.6 | 2023-01-07 | Buy |
| Sigma-Aldrich | A63007 | 4-Amino-3-methylbenzoic acid 98% | 2486-70-6 | 10g | $426 | 2023-01-07 | Buy |
| TCI Chemical | A1353 | 4-Amino-3-methylbenzoic Acid >98.0%(HPLC)(T) | 2486-70-6 | 5g | $56 | 2025-07-31 | Buy |
| TCI Chemical | A1353 | 4-Amino-3-methylbenzoic Acid >98.0%(HPLC)(T) | 2486-70-6 | 25g | $167 | 2025-07-31 | Buy |
| TRC | A614585 | 4-Amino-3-methylbenzoic Acid | 2486-70-6 | 10g | $60 | 2021-12-16 | Buy |
4-Amino-3-methylbenzoic acid Chemical Properties,Uses,Production
Chemical Properties
beige or light buff to orange
Uses
4-Amino-3-methylbenzoic Acid is used in preparation of Amide-substituted Benzo[d]imidazole compounds as selective inhibitors of indoleamine-2,3-dioxygenases.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
3113-71-1
2486-70-6
At room temperature and under hydrogen atmosphere, 3-methyl-4-nitrobenzoic acid (100 g, 552.04 mmol) was dissolved in methanol (2000 mL) followed by addition of palladium carbon catalyst (5.0 g). The reaction mixture was stirred continuously at room temperature for 24 hours. Upon completion of the reaction, the solid catalyst was removed by filtration. The filtrate was concentrated under reduced pressure to give the light yellow solid product 4-amino-3-methylbenzoic acid (80 g, 96% yield).
References
[1] Advanced Synthesis and Catalysis, 2010, vol. 352, # 9, p. 1451 - 1454
[2] Patent: WO2014/66795, 2014, A1. Location in patent: Paragraph 0175
[3] Journal of Organic Chemistry, 2008, vol. 73, # 21, p. 8631 - 8634
[4] Patent: CN106831460, 2017, A. Location in patent: Paragraph 0029-0059
[5] Patent: CN107501106, 2017, A. Location in patent: Paragraph 0025-0047
4-Amino-3-methylbenzoic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8770 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21616 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29850 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2954 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10035 | 58 |
View Lastest Price from 4-Amino-3-methylbenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-06 | 4-Amino-3-methylbenzoic acid
2486-70-6
|
US $78.26 / Kg/Drum | 25Kg/Drum | 98.50%HPLC | 20tons/month | Asia Chem I and E (Jiangsu) Co Ltd | |
 |
2025-11-06 | 4-Amino-3-methylbenzoic acid
2486-70-6
|
US $10.00 / KG | 100KG | 99% | 100 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-08-08 | Methylene Blue trihydrate
2486-70-6
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Sichuan Zhuoyu Yantang Technology Co., Ltd. |
-
- 4-Amino-3-methylbenzoic acid
2486-70-6
- US $78.26 / Kg/Drum
- 98.50%HPLC
- Asia Chem I and E (Jiangsu) Co Ltd
-
- 4-Amino-3-methylbenzoic acid
2486-70-6
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Methylene Blue trihydrate
2486-70-6
- US $0.00 / KG
- 99%
- Sichuan Zhuoyu Yantang Technology Co., Ltd.
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