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D(+)-Phenylalaninol

D(+)-Phenylalaninol structure

CAS No.: 5267-64-1

Chemical Name:: D(+)-Phenylalaninol

Synonyms: D-PHENYLALANINOL;H-D-PHE-OL;D-Phenylalanino;(R)-2-AMINO-3-PHENYL-1-PROPANOL;(2R)-2-amino-3-phenylpropan-1-ol;(R)-2-AMINO-3-PHENYL-PROPAN-1-OL;H-D-Phen-ol;R-228060-001;D-PHENYLANINOL;D-phenylalanol

CBNumber:: CB9741308

Molecular Formula:: C9H13NO

Molecular Weight:: 151.21

MDL Number:: MFCD00064298

MOL File:: 5267-64-1.mol

MSDS File:: SDS

Last updated:2025-10-14 11:07:04

Product description	Number	Pack Size	Price
(R)-(+)-2-Amino-3-phenyl-1-propanol 98%	284491	5g	$142
D-Phenylalaninol >98.0%(GC)(T)	P1289	5g	$72
D-Phenylalaninol >98.0%(GC)(T)	P1289	25g	$218
D-Phenylalaninol	019430	5g	$403
(R)-(+)-2-AMINO-3-PHENYL-1-PROPANOL 95.00%	AAA0003162	5G	$813.12
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D(+)-Phenylalaninol Properties

Melting point	93-95 °C(lit.)
Boiling point	122 °C / 4mmHg
alpha	23 º (c=1.2, 1 N HCl 22 ºC)
Density	1.0406 (rough estimate)
refractive index	23.5 ° (C=1.2, 1mol/L HCl)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in Dichloromethane, Ethyl Acetate, Methanol.
pka	12.85±0.10(Predicted)
form	Crystalline Powder and Chunks
color	White to yellow
optical activity	[α]/D +22.8°, c = 1.2 in 1 M HCl
Sensitive	Air Sensitive
BRN	4665408
InChI	InChI=1/C9H13NO/c10-9(7-11)6-8-4-2-1-3-5-8/h1-5,9,11H,6-7,10H2/t9-/s3
InChIKey	STVVMTBJNDTZBF-DJEYLCQNNA-N
SMILES	C(C1C=CC=CC=1)[C@@H](N)CO \|&1:7,r\|
CAS DataBase Reference	5267-64-1(CAS DataBase Reference)
FDA UNII	A6QY3U3O3V
UNSPSC Code	12352116
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314

Precautionary statements

P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363

Hazard Codes

C,Xi

Risk Statements

Safety Statements

26-36/37/39-45-27

RIDADR

UN 3259 8/PG 3

WGK Germany

10-23

HazardClass

IRRITANT

HazardClass

PackingGroup

III

HS Code

29221990

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	0
3		0

D(+)-Phenylalaninol price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	284491	(R)-(+)-2-Amino-3-phenyl-1-propanol 98%	5267-64-1	5g	$142	2023-01-07	Buy
TCI Chemical	P1289	D-Phenylalaninol >98.0%(GC)(T)	5267-64-1	5g	$72	2025-07-31	Buy
TCI Chemical	P1289	D-Phenylalaninol >98.0%(GC)(T)	5267-64-1	25g	$218	2025-07-31	Buy
Usbiological	019430	D-Phenylalaninol	5267-64-1	5g	$403	2021-12-16	Buy
American Custom Chemicals Corporation	AAA0003162	(R)-(+)-2-AMINO-3-PHENYL-1-PROPANOL 95.00%	5267-64-1	5G	$813.12	2021-12-16	Buy

Product number	Packaging	Price	Buy
284491	5g	$142	Buy
P1289	5g	$72	Buy
P1289	25g	$218	Buy
019430	5g	$403	Buy
AAA0003162	5G	$813.12	Buy

D(+)-Phenylalaninol Chemical Properties,Uses,Production

Detected method

Phenomena, including gelation and fluorescence, are used as easily detected sensors of chiral recognition. Qin et al. have developed a new type of isomerized diphenylalanine-based supramolecular gel (LFDF), which showed the visible enantiomeric discrimination of phenylalaninol enantiomers via fluorescence and gelation measurements. The addition of L- or D-phenylalaninol to the peptide gel led to complete collapse within one minute after adding the L-form, which was not observed in D-phenylalaninol. Meanwhile, by doping with the fluorescent dye thioflavin T (ThT), the prepared ThT-LFDF gel system can sensitively detect the L/D-phenylalanine enantiomer through fluorescence quenching, which has the advantages of visualization, easy manipulation, and high detection sensitivity.

Description

D-phenylalanine is the D-enantiomer of phenylalanine. It is a conjugate base of a D-phenylalaninium and an enantiomer of a L-phenylalanine. D-Phenylalanine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). It may be light-sensitive. This compound reacts with strong oxidizing agents, acids and bases. It acts as a weak acid in solution.

Chemical Properties

white to light yellow crystal powde

Uses

D-Phenylalaninol is used as a chiral auxiliary for asymmetric Michael reactions. It is an enantiomer of L-Phenylalaninol, an inhibitor of intestinal Phenylalanine absorption. It acts as an inhibiting agent to the enzymes which are responsible for the breakdown of endorphins.

Purification Methods

It can be recrystallised from Et2O, *C6H6/pet ether (b 40-60o) or toluene and distilled in a vacuum. It has been purified by dissolving in Et2O, drying over K2CO3, filtering, evaporating to a small volume, cooling in ice and collecting the plates. Store them in the presence of KOH (i.e. CO2—free atm). [Karrer & Ehrhardt Helv Chim Acta 34 3203 1951, Oeda Bull Chem Soc Jpn 13 465 1938.] The picrate has m 141-141.5o (from EtOH/pet ether). The hydrogen oxalate has m 177o, 161-162o [Hunt & McHale J Chem Soc 2073 1957]. The racemate has m 87-88o from *C6H6/pet ether (75-77o from Et2O), and the hydrochloride has m 139-141o [Fodor et al. J Chem Soc 1858 1951]. [Beilstein 13 IV 1920.]

D(+)-Phenylalaninol Preparation Products And Raw materials

Raw materials

(R)-2-Amino-3-phenylpropionic acid methylester FMOC-D-PHENYLALANINOL (2R)-3-PHENYL-1,2-PROPANEDIAMINE D-Phenylalanine

Preparation Products

Cbz-D-Phenylalaninol 1-[(4R)-4-(phenylmethyl)-2-thioxo-3-thiazolidinyl]-Ethanone TMC-58B

D(+)-Phenylalaninol Suppliers

Global( 545)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39927	58
Zhengzhou Anbu Chem Co.,Ltd	+86-0371-88006763; +8615988602810	sales@anbuchem.com	China	3000	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8770	58
Sichuan Zhuoyu Yantang Technology Co., Ltd.	+8613288715578	sales@sichuanzyyt.com	China	12242	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5251	58
Sichuan HongRi Pharma-Tech Co.,Ltd	+8617390183901	cynthia@enlaibio.com	China	1100	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16515	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13505	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21617	55

Supplier	Advantage
Chongqing Chemdad Co., Ltd	58
Zhengzhou Anbu Chem Co.,Ltd	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Sichuan Zhuoyu Yantang Technology Co., Ltd.	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Sichuan HongRi Pharma-Tech Co.,Ltd	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55

D(+)-Phenylalaninol: Synthesis, Chiral Recognition, and Gastric Acid Secretion Inhibition
D(+)-Phenylalaninol, synthesized via Cu-catalyzed hydrogenation, aids chiral recognition and significantly inhibits centrally ....
Oct 14，2025

View Lastest Price from D(+)-Phenylalaninol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-07	d-phe-ol 5267-64-1	US $0.00-0.00 / kg	1kg	98%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2025-11-06	D(+)-Phenylalaninol 5267-64-1	US $0.00 / Kg/Drum	1KG	98%min	1000kg	WUHAN FORTUNA CHEMICAL CO., LTD
2025-11-06	D(+)-Phenylalaninol 5267-64-1	US $10.00 / KG	100KG	99%	100 mt	Hebei Chuanghai Biotechnology Co., Ltd

d-phe-ol
5267-64-1
US $0.00-0.00 / kg
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

D(+)-Phenylalaninol
5267-64-1
US $0.00 / Kg/Drum
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

D(+)-Phenylalaninol
5267-64-1
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

D(+)-Phenylalaninol Spectrum

D(+)-Phenylalaninol(5267-64-1)MS D(+)-Phenylalaninol(5267-64-1)¹HNMR D(+)-Phenylalaninol(5267-64-1)¹³CNMR D(+)-Phenylalaninol(5267-64-1)IR1 D(+)-Phenylalaninol(5267-64-1)IR2 D(+)-Phenylalaninol(5267-64-1)Raman

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D-(+)-Phenylalinol S/R-Phenylalaninol BENZENEPROPANOL, .BETA.-AMINO-, (.BETA.R)- D-Penylalaninol D-PHEYLALANINOL D-PHENYLANINOL (D)-(+)-2-PHENYLALANINOL / D-(+)-2-AMINO-3-PHENYL-1-PROPANOL D-Phenylalaninol(R+Phenylalaninol) Benzenepropanol, beta-amino-, (R)- D-Phenylalaninol ,98% (R)-3-Phenyl-2-amino-1-propanol (R)-3-Phenyl-2-aminopropane-1-ol (αR)-α-(Hydroxymethyl)benzeneethanamine H-D-Phen-ol D(+)-2-Amino-3-phenyl-1-propanol,98% D-PHENYLALANINOL ((R)-(+)-2-AMINO-3-PHENYL-1-PROPANOL) ((1R)-1-HydroxyMethyl-2-phenylethyl)aMine (2R)-2-AMino-3-phenyl-1-propanol (R)-(+)-2-AMino-3-phenyl-1-glycinol (R)-2-AMino-1-hydroxy-3-phenylpropane (R)-2-BenzylethanolaMine (βR)-β-AMino-benzenepropanol D-Phenylalaninol, (2R)-2-Amino-1-hydroxy-3-phenylpropane BENZENEPROPANOL, B-AMINO-, (BR)- D-(R)-PHENYLALANINOL D(+)-PHENYLALANINOL D-ALPHA-PHENYLALANINOL D(+)-2-AMINO-3-PHENYL-1-PROPANOL D-2-PHENYLALANINOL H-D-PHENYLALANINOL (R)-(+)-2-AMINO-3-PHENYL-1-PROPANOL (R)-(+)-PHENYLALANINOL (R)-PHENYLALANINOL PHENYLALANINOL-D (R)-2-amino-3-phenylpropanol (R)-2-Amino-3-phenyl-1-propanol D(+)-Phenylalaninol D(+)-2-Amino-3-phenyl-1-propanol D-2-Amino-3-phenyl-1-propanol,99%e.e. (R)-(+)-2-Amino-3-phenyl-1-propanol 98% R-228060-001 D-Phenylalaninol> Benzenepropanol, β-amino-, (βR)- D(+)-Phenylalaninol USP/EP/BP D-(+)-2-Amino-3-phenyl-1-proanol (+)-D-Phenylalaninol (2R)-2-amino-3-phenylpropan-1-ol D-PHENYLALANINOL (R)-2-AMINO-3-PHENYL-1-PROPANOL (R)-2-AMINO-3-PHENYL-PROPAN-1-OL D-Phenylalanino H-D-PHE-OL (2S)-2-amino-1-phenylpropan-1-ol (R)-(+)-2-Amino-3-phenyl-1-propanol D-Phenylalaninol, 95% Benzenepropanol, β-amino-, (βR)- D-phenylalanol 5267-64-1 15267-64-1 Amino Alcohols (Chiral)