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D(+)-Phenylalaninol

D(+)-Phenylalaninol structure

CAS No.: 5267-64-1

Chemical Name:: D(+)-Phenylalaninol

Synonyms: D-PHENYLALANINOL;(2R)-2-amino-3-phenylpropan-1-ol;(R)-PHENYLALANINOL;(R)-(+)-2-AMINO-3-PHENYL-1-PROPANOL;H-D-PHE-OL;D-Phenylalanino;(R)-2-AMINO-3-PHENYL-1-PROPANOL;(R)-2-AMINO-3-PHENYL-PROPAN-1-OL;H-D-Phen-ol;R-228060-001

CBNumber:: CB9741308

Molecular Formula:: C9H13NO

Molecular Weight:: 151.21

MDL Number:: MFCD00064298

MOL File:: 5267-64-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-19 22:55:08

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D(+)-Phenylalaninol Properties

Melting point	93-95 °C(lit.)
Boiling point	122 °C / 4mmHg
alpha	23 º (c=1.2, 1 N HCl 22 ºC)
Density	1.0406 (rough estimate)
refractive index	23.5 ° (C=1.2, 1mol/L HCl)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in Dichloromethane, Ethyl Acetate, Methanol.
pka	12.85±0.10(Predicted)
form	Crystalline Powder and Chunks
color	White to yellow
optical activity	[α]/D +22.8°, c = 1.2 in 1 M HCl
Sensitive	Air Sensitive
BRN	4665408
InChI	InChI=1/C9H13NO/c10-9(7-11)6-8-4-2-1-3-5-8/h1-5,9,11H,6-7,10H2/t9-/s3
InChIKey	STVVMTBJNDTZBF-DJEYLCQNNA-N
SMILES	C(C1C=CC=CC=1)[C@@H](N)CO \|&1:7,r\|
CAS DataBase Reference	5267-64-1(CAS DataBase Reference)
FDA UNII	A6QY3U3O3V
UNSPSC Code	12352116
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314

Precautionary statements

P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363

PPE

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Hazard Codes

C,Xi

Risk Statements

Safety Statements

26-36/37/39-45-27

RIDADR

UN 3259 8/PG 3

WGK Germany

10-23

HazardClass

IRRITANT

HazardClass

PackingGroup

III

HS Code

29221990

Storage Class

8A - Combustible corrosive hazardous materials

Hazard Classifications

Eye Dam. 1
Skin Corr. 1B

REACH Registrations

Active

Limited Quantities

5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	0
3		0

D(+)-Phenylalaninol price More Price(71)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	284491	(R)-(+)-2-Amino-3-phenyl-1-propanol 98%	5267-64-1	5g	$142	2023-01-07	Buy
TCI Chemical	P1289	D-Phenylalaninol >98.0%(GC)(T)	5267-64-1	5g	$72	2026-04-30	Buy
TCI Chemical	P1289	D-Phenylalaninol >98.0%(GC)(T)	5267-64-1	25g	$218	2026-04-30	Buy
Usbiological	288383	D-Phenylalaninol Asreported	5267-64-1	2g	$332	2026-06-03	Buy
Usbiological	288383	D-Phenylalaninol Asreported	5267-64-1	5g	$486	2026-06-03	Buy

Product number	Packaging	Price	Buy
284491	5g	$142	Buy
P1289	5g	$72	Buy
P1289	25g	$218	Buy
288383	2g	$332	Buy
288383	5g	$486	Buy

D(+)-Phenylalaninol Chemical Properties,Uses,Production

Detected method

Phenomena, including gelation and fluorescence, are used as easily detected sensors of chiral recognition. Qin et al. have developed a new type of isomerized diphenylalanine-based supramolecular gel (LFDF), which showed the visible enantiomeric discrimination of phenylalaninol enantiomers via fluorescence and gelation measurements. The addition of L- or D-phenylalaninol to the peptide gel led to complete collapse within one minute after adding the L-form, which was not observed in D-phenylalaninol. Meanwhile, by doping with the fluorescent dye thioflavin T (ThT), the prepared ThT-LFDF gel system can sensitively detect the L/D-phenylalanine enantiomer through fluorescence quenching, which has the advantages of visualization, easy manipulation, and high detection sensitivity.

Description

D-phenylalanine is the D-enantiomer of phenylalanine. It is a conjugate base of a D-phenylalaninium and an enantiomer of a L-phenylalanine. D-Phenylalanine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). It may be light-sensitive. This compound reacts with strong oxidizing agents, acids and bases. It acts as a weak acid in solution.

Chemical Properties

white to light yellow crystal powde

Uses

D-Phenylalaninol is used as a chiral auxiliary for asymmetric Michael reactions. It is an enantiomer of L-Phenylalaninol, an inhibitor of intestinal Phenylalanine absorption. It acts as an inhibiting agent to the enzymes which are responsible for the breakdown of endorphins.

Purification Methods

It can be recrystallised from Et2O, *C6H6/pet ether (b 40-60o) or toluene and distilled in a vacuum. It has been purified by dissolving in Et2O, drying over K2CO3, filtering, evaporating to a small volume, cooling in ice and collecting the plates. Store them in the presence of KOH (i.e. CO2—free atm). [Karrer & Ehrhardt Helv Chim Acta 34 3203 1951, Oeda Bull Chem Soc Jpn 13 465 1938.] The picrate has m 141-141.5o (from EtOH/pet ether). The hydrogen oxalate has m 177o, 161-162o [Hunt & McHale J Chem Soc 2073 1957]. The racemate has m 87-88o from *C6H6/pet ether (75-77o from Et2O), and the hydrochloride has m 139-141o [Fodor et al. J Chem Soc 1858 1951]. [Beilstein 13 IV 1920.]

D(+)-Phenylalaninol Preparation Products And Raw materials

Raw materials

(R)-2-Amino-3-phenylpropionic acid methylester Fmoc-D-phenylalaninol (2R)-3-Phenyl-1,2-propanediamine D-Phenylalanine

Preparation Products

Cbz-D-Phenylalaninol 1-[(4R)-4-(phenylmethyl)-2-thioxo-3-thiazolidinyl]-Ethanone TMC-58B

D(+)-Phenylalaninol Suppliers

Global( 551)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chongqing Xingcan Pharmaceutical Technology Co., Ltd.	13594048950 19923294409	xingcanyaoye@sina.com	China	1591	58
Nanjing Redwood Fine Chemical Co., Ltd.	158-05183379 15805183379	zjp@redwood.com.cn	China	255	60
Anhui Dexinjia Biopharm Co., Ltd.,	0531-82375887 18245291386	3955164757@qq.com	China	47	58
Hubei Peien Biotechnology Co., Ltd.	13127581762 13127581762	peilingchem@sina.com	China	231	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
INTATRADE GmbH	+49 3493/605464	sales@intatrade.de	Germany	3563	66
ITIC MEDCHEM(SUZHOU) CO.,LTD.	0512-68323967 18015559028	sales@iticmedchem.com	China	528	61
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84

Supplier	Advantage
Shanghai Hanhong Scientific Co.,Ltd.	64
Chongqing Xingcan Pharmaceutical Technology Co., Ltd.	58
Nanjing Redwood Fine Chemical Co., Ltd.	60
Anhui Dexinjia Biopharm Co., Ltd.,	58
Hubei Peien Biotechnology Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
INTATRADE GmbH	66
ITIC MEDCHEM(SUZHOU) CO.,LTD.	61
Alfa Aesar	84

D(+)-Phenylalaninol: Synthesis, Chiral Recognition, and Gastric Acid Secretion Inhibition
D(+)-Phenylalaninol, synthesized via Cu-catalyzed hydrogenation, aids chiral recognition and significantly inhibits centrally ....
Oct 14,2025

View Lastest Price from D(+)-Phenylalaninol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-14	d-phe-ol 5267-64-1		1kg	98%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2026-09-11	D(+)-Phenylalaninol 5267-64-1		1KG	98%min	1000kg	WUHAN FORTUNA CHEMICAL CO., LTD
2026-08-25	D(+)-Phenylalaninol 5267-64-1	$2.20-8.80	1kg	99%	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

d-phe-ol
5267-64-1
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

D(+)-Phenylalaninol
5267-64-1
$0.00
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

D(+)-Phenylalaninol
5267-64-1
$2.20-8.80
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

D(+)-Phenylalaninol Spectrum

D(+)-Phenylalaninol(5267-64-1)MS D(+)-Phenylalaninol(5267-64-1)¹HNMR D(+)-Phenylalaninol(5267-64-1)¹³CNMR D(+)-Phenylalaninol(5267-64-1)IR1 D(+)-Phenylalaninol(5267-64-1)IR2 D(+)-Phenylalaninol(5267-64-1)Raman

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D-(+)-Phenylalinol S/R-Phenylalaninol BENZENEPROPANOL, .BETA.-AMINO-, (.BETA.R)- D-Penylalaninol D-PHEYLALANINOL D-PHENYLANINOL (D)-(+)-2-PHENYLALANINOL / D-(+)-2-AMINO-3-PHENYL-1-PROPANOL D-Phenylalaninol(R+Phenylalaninol) Benzenepropanol, beta-amino-, (R)- D-Phenylalaninol ,98% (R)-3-Phenyl-2-amino-1-propanol (R)-3-Phenyl-2-aminopropane-1-ol (αR)-α-(Hydroxymethyl)benzeneethanamine H-D-Phen-ol D(+)-2-Amino-3-phenyl-1-propanol,98% D-PHENYLALANINOL ((R)-(+)-2-AMINO-3-PHENYL-1-PROPANOL) ((1R)-1-HydroxyMethyl-2-phenylethyl)aMine (2R)-2-AMino-3-phenyl-1-propanol (R)-(+)-2-AMino-3-phenyl-1-glycinol (R)-2-AMino-1-hydroxy-3-phenylpropane (R)-2-BenzylethanolaMine (βR)-β-AMino-benzenepropanol D-Phenylalaninol, (2R)-2-Amino-1-hydroxy-3-phenylpropane BENZENEPROPANOL, B-AMINO-, (BR)- D-(R)-PHENYLALANINOL D(+)-PHENYLALANINOL D-ALPHA-PHENYLALANINOL D(+)-2-AMINO-3-PHENYL-1-PROPANOL D-2-PHENYLALANINOL H-D-PHENYLALANINOL (R)-(+)-PHENYLALANINOL PHENYLALANINOL-D (R)-2-amino-3-phenylpropanol (R)-2-Amino-3-phenyl-1-propanol D(+)-Phenylalaninol D(+)-2-Amino-3-phenyl-1-propanol D-2-Amino-3-phenyl-1-propanol,99%e.e. (R)-(+)-2-Amino-3-phenyl-1-propanol 98% R-228060-001 D-Phenylalaninol> Benzenepropanol, β-amino-, (βR)- D(+)-Phenylalaninol USP/EP/BP D-(+)-2-Amino-3-phenyl-1-proanol (+)-D-Phenylalaninol (R)-2-AMINO-3-PHENYL-1-PROPANOL (R)-2-AMINO-3-PHENYL-PROPAN-1-OL D-Phenylalanino H-D-PHE-OL (2S)-2-amino-1-phenylpropan-1-ol (R)-(+)-2-Amino-3-phenyl-1-propanol D-Phenylalaninol, 95% Benzenepropanol, β-amino-, (βR)- D-phenylalanol (2R)-2-amino-3-phenylpropan-1-ol (R)-(+)-2-AMINO-3-PHENYL-1-PROPANOL (R)-PHENYLALANINOL D-PHENYLALANINOL 5267-64-1 15267-64-1 Amino Alcohols (Chiral)