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3-Chloro-4-fluoronitrobenzene

3-Chloro-4-fluoronitrobenzene structure

CAS No.: 350-30-1

Chemical Name:: 3-Chloro-4-fluoronitrobenzene

Synonyms: 2-CHLORO-1-FLUORO-4-NITROBENZENE;3-Chloro-4-fluoronit;Gefitinib Impurity 92;3-chloro-4-fluorobenzene;3-CHLORO-4-FLUORONITROANILINE;4-FLUORO-3-CHLORONITROBENZENE;3-CHLORO-4-FLUORONITROBENZENE;3-chioro-4-fluoronitrobenzene;1-CHLORO-2-FLUORO-5-NITROBENZENE;2-chloro-1-fluoro-4-nitro-benzen

CBNumber:: CB9743847

Molecular Formula:: C6H3ClFNO2

Molecular Weight:: 175.54

MDL Number:: MFCD00007206

MOL File:: 350-30-1.mol

MSDS File:: SDS

Last updated:2025-07-24 18:11:58

Product description	Number	Pack Size	Price
2-Chloro-1-fluoro-4-nitrobenzene 98%	233234	25g	$122.5
3-Chloro-4-fluoronitrobenzene >95.0%(GC)	C1041	25g	$16
3-Chloro-4-fluoronitrobenzene >95.0%(GC)	C1041	250g	$96
3-Chloro-4-fluoronitrobenzene	C368300	25g	$105
3-Chloro-4-fluoronitrobenzene 98%	JK447865	25g	$107
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3-Chloro-4-fluoronitrobenzene Properties

Melting point	40-42 °C(lit.)
Boiling point	227-232°C
Density	1.61
Flash point	>230 °F
storage temp.	Sealed in dry,Room Temperature
solubility	soluble in Methanol
form	powder to crystal
color	White to Light yellow to Green
BRN	1944997
InChI	InChI=1S/C6H3ClFNO2/c7-5-3-4(9(10)11)1-2-6(5)8/h1-3H
InChIKey	DPHCXXYPSYMICK-UHFFFAOYSA-N
SMILES	C1(F)=CC=C([N+]([O-])=O)C=C1Cl
CAS DataBase Reference	350-30-1(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	8H6U84X075
NIST Chemistry Reference	3-Chloro-4-fluoronitrobenzene(350-30-1)
EPA Substance Registry System	3-Chloro-4-fluoronitrobenzene (350-30-1)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H302-H315-H318-H335

Precautionary statements

P261-P280-P305+P351+P338

Hazard Codes

Xn,Xi

Risk Statements

22-37/38-41-36/37/38-20/21/22

Safety Statements

26-39-36/37/39

RIDADR

2811

WGK Germany

RTECS

CZ0720000

Hazard Note

Irritant

HazardClass

6.1

PackingGroup

III

HS Code

29049090

NFPA 704

	1
2		0

3-Chloro-4-fluoronitrobenzene price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	233234	2-Chloro-1-fluoro-4-nitrobenzene 98%	350-30-1	25g	$122.5	2025-07-31	Buy
TCI Chemical	C1041	3-Chloro-4-fluoronitrobenzene >95.0%(GC)	350-30-1	25g	$16	2025-07-31	Buy
TCI Chemical	C1041	3-Chloro-4-fluoronitrobenzene >95.0%(GC)	350-30-1	250g	$96	2025-07-31	Buy
TRC	C368300	3-Chloro-4-fluoronitrobenzene	350-30-1	25g	$105	2021-12-16	Buy
Frontier Specialty Chemicals	JK447865	3-Chloro-4-fluoronitrobenzene 98%	350-30-1	25g	$107	2021-12-16	Buy

Product number	Packaging	Price	Buy
233234	25g	$122.5	Buy
C1041	25g	$16	Buy
C1041	250g	$96	Buy
C368300	25g	$105	Buy
JK447865	25g	$107	Buy

3-Chloro-4-fluoronitrobenzene Chemical Properties,Uses,Production

Synthesis

In certain instances, when both chloro and nitro may act as a leaving group, a surprising selectivity of one over the other is observed, for example chloro-2,5- dinitrobenzene was converted to 4-fluoro-3-chloronitrobenzene.
3-Chloro-4-fluoronitrobenzene

Chemical Properties

white to light yellow crystal powder

Uses

2-Chloro-1-fluoro-4-nitrobenzene has been used in synthesis of:

benzoimidolones on Ameba resin
methyl 6,7,8,9-tetrahydropyrido[1,2-a]indol-10-ylacetate

Uses

2-Chloro-1-fluoro-4-nitrobenzene is an intermediate used in synthesis of benzoimidolones on Ameba resin and methyl 6,7,8,9-tetrahydropyrido[1,2-a]indol-10-ylacetate.

Synthesis Reference(s)

The Journal of Organic Chemistry, 63, p. 8448, 1998 DOI: 10.1021/jo981557o
Synthetic Communications, 21, p. 505, 1991 DOI: 10.1080/00397919108016776

General Description

2-Chloro-1-fluoro-4-nitrobenzene undergoes reduction in the presence of Mo(CO)₆ and 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) under microwave irradiation to yield a mixture of 3-chloro-4-fluoroaniline and 3-chloro-4-ethoxyaniline.

References

[1] Catalysis Today, 2012, vol. 198, # 1, p. 300 - 304
[2] Chemical Communications, 1996, # 3, p. 297 - 298
[3] Chemical Communications, 1996, # 3, p. 297 - 298
[4] Journal of Fluorine Chemistry, 2004, vol. 125, # 5, p. 701 - 704
[5] Advanced Synthesis and Catalysis, 2008, vol. 350, # 17, p. 2677 - 2682

3-Chloro-4-fluoronitrobenzene synthesis

Synthesis of 3-Chloro-4-fluoronitrobenzene from 4-Fluoronitrobenzene

3-Chloro-4-fluoronitrobenzene Preparation Products And Raw materials

Raw materials

4-Fluoronitrobenzene Fluorobenzene Dioctadecyl dimethyl ammonium chloride 3,4-Dinitrochlorobenzene 4-Chloro-3-fluoronitrobenzene

Sulfolane 2-Chlorofluorobenzene 2,4-Dinitrofluorobenzene 1,2-Dichlorobenzene 3,4-Dichloronitrobenzene

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Preparation Products

Norfloxacin 1,3-Dichloro-4-fluorobenzene 3-CHLORO-4-MORPHOLINOANILINE 3,4-Difluoronitrobenzene 1-(2-CHLORO-4-NITRO-PHENYL)-PIPERIDINE

(2-chloro-4-nitrophenyl)hydrazine

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3-Chloro-4-fluoronitrobenzene Suppliers

Global( 399)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20173	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13505	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21616	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29850	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2930	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58
Hubei Jusheng Technology Co.,Ltd.	58
Xiamen AmoyChem Co., Ltd	58
Hubei xin bonus chemical co. LTD	58

View Lastest Price from 3-Chloro-4-fluoronitrobenzene manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-09-25	3-Chloro-4-fluoronitrobenzene 350-30-1	US $100.00-1.00 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2022-02-19	3-Chloro-4-fluoronitrobenzene 350-30-1	US $0.00 / KG	1KG	97.4%	100 tons	Honest Joy Holdings Limited
2021-11-02	3-Chloro-4-fluoronitrobenzene 350-30-1	US $79.00 / KG	1KG	99	10T	Baoji Guokang Healthchem co.,ltd

3-Chloro-4-fluoronitrobenzene
350-30-1
US $100.00-1.00 / KG
99%
Henan Fengda Chemical Co., Ltd

3-Chloro-4-fluoronitrobenzene
350-30-1
US $0.00 / KG
97.4%
Honest Joy Holdings Limited

3-Chloro-4-fluoronitrobenzene
350-30-1
US $79.00 / KG
99
Baoji Guokang Healthchem co.,ltd

3-Chloro-4-fluoronitrobenzene Spectrum

3-Chloro-4-fluoronitrobenzene(350-30-1)MS 3-Chloro-4-fluoronitrobenzene(350-30-1)¹HNMR 3-Chloro-4-fluoronitrobenzene(350-30-1)¹³CNMR 3-Chloro-4-fluoronitrobenzene(350-30-1)IR1 3-Chloro-4-fluoronitrobenzene(350-30-1)IR2 3-Chloro-4-fluoronitrobenzene(350-30-1)Raman

350-30-1(3-Chloro-4-fluoronitrobenzene)Related Search:

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2-chloro-1-fluoro-4-nitro-benzen Benzene, 2-chloro-1-fluoro-4-nitro- Benzene,2-chloro-1-fluoro-4-nitro- 1-CHLORO-2-FLUORO-5-NITROBENZENE 3-CHLORO-4-FLUORONITROBENZENE 4-FLUORO-3-CHLORONITROBENZENE 3-chloro-4-fluorobenzene 3-CHLORO-4-FLUORONITROANILINE 3-Chloro-4-fluoronitrobenzene 98% 3-Chloro-4-fluoronitrobenzene98% 1-Nitro-3-chloro-4-fluorobenzene 1-Nitro-4-fluoro-3-chlorobenzene 3-Chloro-4-fluoro-1-nitrobenzene 3-Chloro-4-fluoronit 3-chioro-4-fluoronitrobenzene 3-Chloro-4-fluoronitrobenzene > Gefitinib Impurity 92 3-Chloro-4-fluoronitrobenzene ISO 9001：2015 REACH 2-CHLORO-1-FLUORO-4-NITROBENZENE Geftinib Impurity : 3-Chloro-4-fluro-nitribenzene 350-30-1 350-31-1 C6H3ClFNO2 ClC6H3FNO2 Nitro Compounds Organic Building Blocks Nitrogen Compounds Building Blocks Nitro Compounds Nitrogen Compounds Organic Building Blocks Fluorinated benzene series