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PROMETHAZINE

PROMETHAZINE
PROMETHAZINE structure
CAS No.
60-87-7
Chemical Name:
PROMETHAZINE
Synonyms
Dimapp;Fargan;Procit;Prorex;WY 509;3277 RP;Aprobit;A-91033;Avomine;Fenazil
CBNumber:
CB9744071
Molecular Formula:
C17H20N2S
Formula Weight:
284.42
MOL File:
60-87-7.mol

PROMETHAZINE Properties

Melting point:
60℃
Boiling point:
bp3 190-192°
Density 
1.131
refractive index 
1.6000 (estimate)
pka
pKa 9.1(H2O,t undefined) (Uncertain)

PROMETHAZINE price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PH011183 N,N-dimethyl-1-(10H-phenothiazin-10-yl)-2-propanamine AldrichCPR 500mg $133 2018-11-23 Buy

PROMETHAZINE Chemical Properties,Uses,Production

Uses

Anti-emetic; antihistaminic.

Definition

ChEBI: A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.

brand name

Phenergan (Wyeth).

World Health Organization (WHO)

Introduced in 1946, promethazine, a phenothiazine derivative has a variety of pharmacological properties. At present it is mainly used as an antihistamine and anti-motion-sickness drug. Promethazine is listed in the WHO Model List of Essential Drugs.

General Description

Crystals. Melting point 60°C. Used as an antihistaminic.

Air & Water Reactions

Turns blue on prolonged exposure to air and moisture.

Reactivity Profile

PROMETHAZINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable or toxic gases may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

SYMPTOMS: Symptoms of PROMETHAZINE include leucopenia; agranulocytosis; confusion; convulsions; stupor; and it potentiates the action of central nervous system depressants.

Fire Hazard

Flash point data for PROMETHAZINE are not available, however PROMETHAZINE is probably combustible.

Safety Profile

Poison by ingestion, intravenous, intramuscular, intraperitoneal, and subcutaneous routes. Human systemic effects by ingestion: pupillary dilation, wakefulness, hallucinations, and distorted perceptions. An experimental teratogen. Other experimental reproductive effectsHuman mutation data reported. A severe eye irritant. When heated to decomposition it emits very toxic fumes of NOx and SOx

PROMETHAZINE Preparation Products And Raw materials

Raw materials

Preparation Products


PROMETHAZINE Suppliers

Global( 34)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23980 58
BOC Sciences
1-631-619-7922
1-631-614-7828 inquiry@bocsci.com United States 20115 58
Syntechem Co.,Ltd Please Email
E-Mail Inquiry info@syntechem.com China 13010 57
Hangzhou Yuhao Chemical Technology Co., Ltd 0571-82693216
+86-571-82880190 info@yuhaochemical.com China 9406 52
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979
021-33632979 zijuecai@targetmol.com China 2994 58
HangZhou YuHao Chemical Technology Co., Ltd. 0571-82693216
0571-82880190 info@yuhaochemical.com China 1853 58
Chizhou Kailong Import and Export Trade Co., Ltd. Please Email
- xg01_gj@163.com China 9562 50
Alta Scientific Co., Ltd. (0086) 22-6537-8550; 185-2256-9193; 185-2256-9194
(0086) 22-2532-9655 contact@altascientific.com China 8312 55
Shanghai Boyners Pharm-Tech Co., Ltd. +86 (21) 5458-1719
021-31329586 MSN: xurui.li@hotmail.com mkt@boynerspharm.com China 1724 55

60-87-7(PROMETHAZINE)Related Search:


  • (2-Dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine
  • (Dimethylamino-2-propyl-10-phenothiazine hydrochloride
  • 10-(2-(Dimethylamino)-2-methylethyl)phenothiazine
  • 10-[2-(Dimethylamino)propyl]phenothiazine
  • 10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-
  • 3277 RP
  • 3389 R.P.
  • 4182 R.P.
  • A-91033
  • Aprobit
  • PROMETHAZINE
  • Promethaine
  • N,N,a-Trimethyl-10H-phenothiazine-10-ethanamine
  • NSC 30321
  • 10H-Phenothiazine-10-ethanamine, N,N,a-trimethyl- (9CI)
  • Phenothiazine, 10-[2-(dimethylamino)propyl]- (8CI)
  • Promethazine (base and/or unspecified salts)
  • 10-(2-DIMETHYLAMINOPROPYL)-PHENOTHIAZIN
  • 10-[2-(Dimethylamino)propyl]-10H-phenothiazine
  • dimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)amine
  • N,N-dimethyl-1-phenothiazin-10-yl-propan-2-amine
  • N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine
  • N,N-diMethyl-1-(10H-phenothiazin-10-yl)propan-2-aMine
  • 10H-Phenothiazine-10-ethanaMine,N,N,a-triMethyl-
  • Avomine
  • Dimapp
  • Dimethylamino-isopropyl-phenthiazin
  • Diphergan
  • Diprazine
  • Diprozin
  • Fargan
  • Fenazil
  • Fenetazina
  • Hiberna
  • Histargan
  • Iergigan
  • Isophenergan
  • Isopromethazine
  • Lercigan
  • Lergigan
  • Lilly 01516
  • Lilly 1516
  • N-(2'-Dimethylamino-2'-methyl)ethylphenothiazine
  • N,N-Dimethyl-1-(10H-phenothiazin-10-yl)-2-propanamine
  • NCI-C60673
  • N-Dimethylamino-2-methylethyl thiodiphenylamine
  • Phargan
  • Phenargan
  • Phenothiazine, 10-[2-(dimethylamino)propyl]-
  • Phensedyl
  • Pilpophen
  • Pipolphen
  • Proazaimine
  • Proazamine
  • Procit
  • Promazinamide
  • Prometasin
  • Prometazin
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