ChemicalBook >> CAS DataBase List >>Tropisetron hydrochloride
Tropisetron hydrochloride
- CAS No.
- 105826-92-4
- Chemical Name:
- Tropisetron hydrochloride
- Synonyms
- TROPISETRON HCL;Novaban;SDZ-ICS 930;Novaban / ICS 205930;TropisetronHcl/Mesylate;ropisetronhydrochloride;α-L-Rhamnose monohydrate;Tropisetran hydrochloride;TROPISETRON HYDROCHLORIDE;Triopisetron hydrochloride
- CBNumber:
- CB9761399
- Molecular Formula:
- C17H21ClN2O2
- Molecular Weight:
- 320.81
- MDL Number:
- MFCD02313825
- MOL File:
- 105826-92-4.mol
Last updated:2023-10-25 17:20:02
| Melting point | 283-285°C |
|---|---|
| RTECS | NL6012520 |
| storage temp. | 2-8°C |
| solubility | H2O: >10mg/mL |
| form | solid |
| color | White to Light yellow |
| Water Solubility | Soluble in water |
| Merck | 14,9783 |
| InChI | InChI=1/C17H20N2O2.ClH/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16;/h2-5,10-13,15H,6-9H2,1H3;1H/t11-,12+,13?,15?; |
| InChIKey | ZAOQBEAHJFSJLY-NBVCILBMNA-N |
| SMILES | C12C=CC=CC=1N=CC2C(=O)OC1C[C@]2([H])N(C)[C@@]([H])(CC2)C1.Cl |&1:14,18,r| |
| CAS DataBase Reference | 105826-92-4(CAS DataBase Reference) |
| FDA UNII | A19338Q2YO |
| NCI Drug Dictionary | Novaban |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P264-P270-P301+P310a-P321-P405-P501a | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29399990 | |||||||||
| Toxicity | mouse,LD50,intravenous,37900ug/kg (37.9mg/kg),Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 40, Pg. 2445, 1998. | |||||||||
| NFPA 704 |
|
Tropisetron hydrochloride price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000616 | Tropisetron hydrochloride European Pharmacopoeia (EP) Reference Standard | 105826-92-4 | y0000616 | $220 | 2024-03-01 | Buy |
| Sigma-Aldrich | T104 | Tropisetron monohydrochloride solid, ≥98% (HPLC) | 105826-92-4 | 50mg | $344.8 | 2024-03-01 | Buy |
| TCI Chemical | T2743 | Tropisetron Hydrochloride >98.0%(HPLC)(T) | 105826-92-4 | 1g | $133 | 2024-03-01 | Buy |
| TCI Chemical | T2743 | Tropisetron Hydrochloride >98.0%(HPLC)(T) | 105826-92-4 | 5g | $455 | 2024-03-01 | Buy |
| Alfa Aesar | J62807 | 3-Tropanylindole-3-carboxylate hydrochloride | 105826-92-4 | 100mg | $206.65 | 2024-03-01 | Buy |
Tropisetron hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White to Off-White Crystalline Solid
Uses
A selective 5-HT3 serotonin receptor antagonist
Uses
Specific serotonin (5-HT3) receptor antagonist. Antiemetic.
Definition
ChEBI: A hydrochloride obtained by combining equimolar amounts of tropisetron and hydrogen chloride.
Biological Activity
Potent, orally active 5-HT 3 receptor antagonist. Antiemetic.
Biochem/physiol Actions
Tropisetron a selective serotonin 5-HT3 receptor antagonist is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy . In the treatment of fibromyalgia syndrome (FMS) tropisetron reduced not only pain perception but also had a favourable effect on cardiac dysfunction during treatment.
storage
Room temperature (desiccate)
Tropisetron hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 324)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Mediking Biopharm Co., Ltd | +undefined15901403431 | sales01@mediking.cn | China | 150 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7786 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
View Lastest Price from Tropisetron hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-01-11 | Tropisetron hydrochloride
105826-92-4
|
US $122.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-03-16 | Tropisetron hydrochloride
105826-92-4
|
US $24.00 / KG | 1KG | 99% | 1000kg | Hebei Duling International Trade Co. LTD | |
 |
2023-03-06 | Tropisetron hydrochloride
105826-92-4
|
US $1.90 / KG | 1KG | 99% | 10 ton | Hebei Guanlang Biotechnology Co,.LTD |
-
- Tropisetron hydrochloride
105826-92-4
- US $122.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- Tropisetron hydrochloride
105826-92-4
- US $24.00 / KG
- 99%
- Hebei Duling International Trade Co. LTD
-
- Tropisetron hydrochloride
105826-92-4
- US $1.90 / KG
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
105826-92-4(Tropisetron hydrochloride)Related Search:
3-TROPANYLINDOLE-3-CARBOXYLATE HYDROCHLORIDE
(3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-INDOLE-3-CARBOXYLIC ACID ESTER MONOHYDROCHLORIDE
TROPISETRON HYDROCHLORIDE 98.5-101.5%
TropisetronHcl/Mesylate
1H-Indole-3-carboxylic acid, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrochloride (1:1)
1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrochloride
Novaban
SDZ-ICS 930
3-Tropanylindole-3-carboxylate monohydrochloride, ICS-205,930, Navoban, 1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester monohydrochloride
Tropisetron monohydrochloride
Novaban / ICS 205930
Tropisetran hydrochloride
(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-Indole-3-carboxylate Hydrochloride
3-Tropanylindole-3-carboxylate monohydrochloride
Tropisetron hydrochloride, >=99%
TROPISETRON HYDROCHLORIDE
(1S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride
Tropisetron monohydrochloride, 99%, a 5-HT3 receptor antagonist and α7-nicotinic receptor agonist
Tropisetron hydrochloride CRS
(1R,3R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride
ropisetronhydrochloride
Tropisetron hydrochloride USP/EP/BP
Triopisetron hydrochloride
endo-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride
Tropisetron HCl (SDZ-ICS-930 HCl)
CAS 105826-92-4 Tropisetron hydrochloride
α-L-Rhamnose monohydrate
TROPISETRON HCL
Tropisetron Hydrochloride, ≥ 98.0%
105826-92-4
105825-92-4
89656-68-4
C17H20N2O2ClH
C17H20N2O2HCl
Serotonin
Serotonin receptor
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals
NAVOBAN
zjh
Antiemetic