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Genistin

Genistin structure

CAS No.: 529-59-9

Chemical Name:: Genistin

Synonyms: GENISTEIN-7-O-GLUCOSIDE;GENISTEIN-7-GLUCOSIDE;genistein 7-O-β-D-glucoside;GENISTIN;NSC 5112;genistine;Genistoside;Genistin ,98%;GENISTIN >99%;Genistin (30 mg)

CBNumber:: CB9769395

Molecular Formula:: C21H20O10

Molecular Weight:: 432.38

MDL Number:: MFCD00016883

MOL File:: 529-59-9.mol

MSDS File:: SDS

Last updated:2023-05-25 18:01:24

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Genistin Properties

Melting point	254°C
Boiling point	256 °C
alpha	D21 -28° (c = 0.6 in 0.02N NaOH); D26 -21.4° (pyridine)
Density	1.642±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: 10 mg/mL
pka	6.12±0.20(Predicted)
color	Off-white
Merck	13,4402
BRN	64479
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week.
InChIKey	ZCOLJUOHXJRHDI-CMWLGVBASA-N
LogP	0.790 (est)
FDA UNII	1POG3SCN5T

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319
Precautionary statements	P261-P305+P351+P338
Safety Statements	22-24/25
WGK Germany	3
RTECS	DJ3093000
F	10
HS Code	29389090

Genistin price More Price(61)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	1288805	Genistin United States Pharmacopeia (USP) Reference Standard	529-59-9	30mg	$1320	2024-03-01	Buy
Sigma-Aldrich	05380590	Genistin primary reference standard	529-59-9	25mg	$555	2023-06-20	Buy
Alfa Aesar	J63445	Genistin, 99+%	529-59-9	100mg	$487	2024-03-01	Buy
Cayman Chemical	14174	Genistin ≥98%	529-59-9	5mg	$61	2024-03-01	Buy
Cayman Chemical	14174	Genistin ≥98%	529-59-9	10mg	$112	2024-03-01	Buy

Product number	Packaging	Price	Buy
1288805	30mg	$1320	Buy
05380590	25mg	$555	Buy
J63445	100mg	$487	Buy
14174	5mg	$61	Buy
14174	10mg	$112	Buy

Genistin Chemical Properties,Uses,Production

Description

Genistin is a natural isoflavone isolated from legumes, including soy and kudzu. It is a phytoestrogen, as it stimulates the growth of estrogen-dependent human breast cancer cells in vivo. Like other isoflavones, genistin promotes the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover. It also increases bone formation in collagen matrix in vivo.

Chemical Properties

White Powder

Uses

Genistin has been used for immune reactivity against influenza viruses in vitro and as an internal standard in isoflavones quantification.

Uses

A derivative of Genistein. Inhibitor

Uses

Glucoside of genistein that inhibits protein tyrosine kinase

Uses

An isoflavone glycoside which is an inactive analog of the PTK inhibitor Genistein.

Definition

ChEBI: Genistein 7-O-beta-D-glucoside is a 7-hydroxyisoflavones 7-O-beta-D-glucoside. It is functionally related to a genistein. It is a conjugate acid of a genistein 7-O-beta-D-glucoside(1-).

General Description

Genistin belongs to the class of isoflavone glycosides generally extracted from soybeans.

Biochem/physiol Actions

Selective inhibitor of mammalian terminal deoxynucleotidyl transferase (TdT), with no measurable effect on mammalian or microbial DNA polymerases.

Purification Methods

Genistin is repeatedly crystallised from hot 80% EtOH/water and treated with charcoal (Nuchar) until free from saponin. The presence of saponin is detected by adding crystals to conc H2SO4 when the citron yellow colour changes to red, then purple. Pure genistin does not change colour. UV in 85% EtOH has max at 262.5nm. [Walter J Am Chem Soc 63 3273 1941, Beilstein 18 III/IV 2732.]

References

1) Uchiyama et al. (2005), Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT): baicalin and genistin; Biochim. Biophys. Acta, 1725 298 2) Choi et al. (2007), Pro-apoptotic effect and cytotoxicity of genistein and genistin in human ovarian cancer SK-OV-3 cells; Life Sci, 80 1403 3) Russo et al. (2006), Genistin inhibits UV light-induced plasmid DNA damage and cell growth in human melanoma cells; J. Nutr. Biochem., 17 103

Genistin Preparation Products And Raw materials

Raw materials

Preparation Products

Sophoricoside

Genistin Suppliers

Global( 330)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9350	55
Nanjing Finetech Chemical Co., Ltd.	025-85710122 17714198479	sales@fine-chemtech.com	CHINA	885	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58

Supplier	Advantage
Hangzhou FandaChem Co.,Ltd.	55
Nanjing Finetech Chemical Co., Ltd.	55
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Chengdu Biopurify Phytochemicals Ltd.	58
Hubei xin bonus chemical co. LTD	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
Shanghai Standard Technology Co., Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from Genistin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-23	Genistin 529-59-9	US $0.00 / MG	20MG	99% HPLC	1000KG	Changsha Staherb Natural Ingredients Co., Ltd.
2023-02-24	Genistin 529-59-9	US $0.00 / mg	5mg	≥98%(HPLC)	10 g	Shanghai Standard Technology Co., Ltd.
2021-07-13	Genistin 529-59-9	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

Genistin
529-59-9
US $0.00 / MG
99% HPLC
Changsha Staherb Natural Ingredients Co., Ltd.

Genistin
529-59-9
US $0.00 / mg
≥98%(HPLC)
Shanghai Standard Technology Co., Ltd.

Genistin
529-59-9
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

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4',5,7-TRIHYDROXYISOFLAVONE 7-GLUCOSIDE 7-O-B-D-GLUCOPRYANOSYL GENISTEIN 7-O-BETA-D-GLUCOPYRANOSIDE GENISTEIN, 7-O-BETA-D-GLUCOPYRANOSIDE GENISTIN GLUCOSYL-7-GENISTEIN 4μ,5,7-Trihydroxyisoflavone 7-glucoside, Genistein 7-glucoside, Genistein-7-O-β-D-glucopyranoside Genistin，Genistein 7-glucoside 7-[(β-D-Glucopyranosyl)oxy]-4',5-dihydroxyisoflavone Genistin ,98% Genistin,4′,5,7-Trihydroxyisoflavone 7-glucoside, Genistein 7-glucoside, Genistein-7-O-β-D-glucopyranoside Genistin (30 mg) genistein,7-o-beta-d-glucoside genistine 7-(-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one Genistein-7--O-Glucopyranoside genistin from glycine max 7-(b-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one Genistein-7-b-O-Glucopyranoside Genistoside NSC 5112 5-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chroMen-7-ylbeta-D-glucopyranoside Genistin (Genistoside) 7-(beta-d-glucopyranosyloxy)-3-(4-hydroxyphenyl)-4h-1-benzopyran-4-on genistein,7-beta-d-glucopyranoside 4,5,7-Trigydroxyisoflavone 7-glucoside Genistin, froM soybean Genistin 4',5,7-Trihydroxyisoflavone 7-glucoside 4H-1-Benzopyran-4-one, 7-(.beta.-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)- GENISTIN >99% GENISTIN WITH HPLC -5-hydroxy-3-(4-hydroxyphenyl)- Genistin - CAS 529-59-9 - Calbiochem Genistein glucoside 5-hydroxy-3-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one Nano Liposomal Genistin Genistin, 99%, from soybean 4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)- genistein7-O-β-D-glucoside 4',5,7-Trihydroxyisoflavone 7-beta-D-Glucopyranoside Genistin USP/EP/BP Genistein-7-O-β-D-glucopyranoside 5-hydroxy-3-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 5-Hydroxy-3-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one Genistin Supplier GENISTEIN-7-GLUCOSIDE GENISTEIN-7-O-GLUCOSIDE genistein 7-O-β-D-glucoside Genistein-7-O-β-D-glucopyranoside Genistin (6CI, 7CI, 8CI) Genistein 7-O-β-D-glucopyranoside, 7-(β-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, NSC 5112 Coumarin Impurity 10 (Coumarin 102) 529-59-9 5529-29-9 C21H20O10 43238 Receptor Tyrosine Kinase Inhibitors Tyrosine Kinase (TK)