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DILEVALOL

CAS No.
75659-07-3
Chemical Name:
DILEVALOL
Synonyms
Levadil;Unicard;Dilevaol;Dilevalon;Sch-19927;DILEVALOL;Dilevalolum;DILEVALOL HCL;(R,R)-Labetalol;Dilevalolum [latin]
CBNumber:
CB9773028
Molecular Formula:
C19H24N2O3
Molecular Weight:
328.41
MDL Number:
MFCD00072111
MOL File:
75659-07-3.mol
Last updated:2023-05-04 17:34:42

DILEVALOL Properties

Boiling point 552.7±50.0 °C(Predicted)
Density 1.200±0.06 g/cm3(Predicted)
pka 8.21±0.31(Predicted)
FDA UNII P6629XE33T

DILEVALOL price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth Carbosynth FL24822 Dilevalol 75659-07-3 10mg $145 2021-12-16 Buy
American Custom Chemicals Corporation API0019482 2-HYDROXY-5-((R)-1-HYDROXY-2-(((R)-4-PHENYLBUTAN-2-YL)AMINO)ETHYL)BENZAMIDE 95.00% 75659-07-3 5MG $498.88 2021-12-16 Buy
Biosynth Carbosynth FL24822 Dilevalol 75659-07-3 50mg $507.5 2021-12-16 Buy
American Custom Chemicals Corporation API0019482 2-HYDROXY-5-((R)-1-HYDROXY-2-(((R)-4-PHENYLBUTAN-2-YL)AMINO)ETHYL)BENZAMIDE 95.00% 75659-07-3 1G $3104.85 2021-12-16 Buy
Crysdot CD12036144 2-Hydroxy-5-((R)-1-hydroxy-2-(((R)-4-phenylbutan-2-yl)amino)ethyl)benzamide 95+% 75659-07-3 1g $1583 2021-12-16 Buy
Product number Packaging Price Buy
FL24822 10mg $145 Buy
API0019482 5MG $498.88 Buy
FL24822 50mg $507.5 Buy
API0019482 1G $3104.85 Buy
CD12036144 1g $1583 Buy

DILEVALOL Chemical Properties,Uses,Production

Description

Dilevalol is a "dual-mechanism" antihypertensive reportedly suitable for a wide range of patients. Its partial beta2-agonist action is expected to induce vasodilation, whereas its beta1-antagonist component may protect against stress-induced hemodynamic charges without altering the cardiac output. Dilevalol is the R,R-isomer of labetalol.

Originator

Schering Plough (USA)

Uses

Specific competitive antagonist at both α-and β-adrenergic receptor sites. Antihypertensive.

Uses

(R,R)-Labetalol is a specific competitive antagonist at both α-and β-adrenergic receptor sites. (R,R)-Labetalol is used as an antihypertensive.

Definition

ChEBI: (R,R)-labetalol is a 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide that has 1R,2R-configuration. It is a conjugate base of a dilevalol(1+).

brand name

Levadil; Dilevalon

World Health Organization (WHO)

Dilevalol, a beta-adrenoreceptor antagonist, was introduced into medicine in 1989 for the treatment of hypertension. Shortly afterwards, its use became associated with isolated cases of hepatic toxicity. Although few cases were reported, the manufacturer discontinued sales in Japan and Portugal, the only countries where the drug was marketed, and withdrew applications for registration elsewhere.

DILEVALOL Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 19)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 94838 76
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2127 70
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15421 60
Shanghai Hekang Biotechnology Co., Ltd. 18939837085 youchemicals@gmail.com China 1813 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55477 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
QUALITY CONTROL SOLUTIONS LTD. 15920483169 ORDERS@QCSRM.COM China 18735 58
2-Hydroxy-5-[(R)-1-hydroxy-2-[[(R)-1-methyl-3-phenylpropyl]amino]ethyl]benzamide Sch-19927 (-)-5-((1R)-1-Hydroxy-2-((1R)-1-methyl-3-phenylpropylamino)ethyl)salicylamid [iupac] (R,R)-Labetalol 2-Hydroxy-5-((1R)-1-hydroxy-2-(((1R)-1-methyl-3-phenylpropyl)amino)ethyl)benzamide Benzamide, 2-hydroxy-5-((1R)-1-hydroxy-2-(((1R)-1-methyl-3-phenylpropyl)amino)ethyl)- DILEVALOL DILEVALOL HCL Dilevaol Dilevalon Levadil Unicard 2-Hydroxy-5-((R)-1-hydroxy-2-(((R)-4-phenylbutan-2-yl)aMino)ethyl)benzaMide Benzamide, 2-hydroxy-5-(1-hydroxy-2-((1-methyl-3-phenylpropyl)amino)ethyl)-, (R-(R*,R*))- Dilevalolum Dilevalolum [latin] 75659-07-3 Amines Aromatics Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals