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Dimethomorph

Dimethomorph Structure
Dimethomorph structure
CAS No.
110488-70-5
Chemical Name:
Dimethomorph
Synonyms
4-(3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)-morpholin (e,z)-4-[3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl]morpholine (e,z)-4-[3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)acryloyl]morpholine 4-(3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)morpholine;dimethomoph;Z-DIMETHOMORPH;3-(4-Chlorophenyl)-3-(3,4-diMethoxyphenyl)-1-Morpholinoprop-2-en-1-one;3-(4-Chlorophenyl)-3-(3,4-diMethoxyphenyl)-1-(4-Morpholinyl)-2-propen-1-one;FORUM;ACROBAT;CME 151;AcrobatWP;Festival C
CBNumber:
CB9774944
Molecular Formula:
C21H22ClNO4
Molecular Weight:
387.86
MDL Number:
MFCD01632781
MOL File:
110488-70-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-10 10:27:34
Product description Number Pack Size Price
Dimethomorph Mixture of E + Z isomers, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland CRM56585 100 mg $174
Dimethomorph mixture of E + Z isomers 46027 100mg $111
Dimethomorph ≥95%(mixtureofcisandtransisomers) 24247 50mg $49
Dimethomorph ≥95%(mixtureofcisandtransisomers) 24247 100mg $82
Dimethomorph ≥95% 24247 50mg $44
More product size
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Dimethomorph Properties

Melting point 125-149°C
Boiling point 584.9±50.0 °C(Predicted)
Density 1.231±0.06 g/cm3(Predicted)
vapor pressure 1 x 10-6 Pa (25 °C)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform: Soluble,Methanol: Soluble
pka -1.19±0.20(Predicted)
Water Solubility 50 mg l-1 (20-23 °C)
form Solid
color White to off-white
Merck 13,3248
BRN 8794474
Henry's Law Constant 4.9×104 mol/(m3Pa) at 25℃, Duchowicz et al. (2020)
Major Application agriculture
environmental
InChI 1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+
InChIKey QNBTYORWCCMPQP-NBVRZTHBSA-N
SMILES COc1ccc(cc1OC)\C(=C\C(=O)N2CCOCC2)c3ccc(Cl)cc3
LogP 2.680
FDA UNII 3EXL2158GV
Pesticides Freedom of Information Act (FOIA) Dimethomorph
EPA Substance Registry System Dimethomorph (110488-70-5)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS08,GHS09
Signal word  Danger
Hazard statements  H360F-H411
Precautionary statements  P202-P273-P280-P308+P313-P391-P405
PPE Eyeshields, Gloves
Hazard Codes  N
Risk Statements  51/53
Safety Statements  61
RIDADR  UN3077 9/PG 3
WGK Germany  2
RTECS  QE0478300
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Aquatic Chronic 2
Repr. 1B
Hazardous Substances Data 110488-70-5(Hazardous Substances Data)
Toxicity LD50 in rats (mg/kg): 321 i.p.; 3900 orally; >5000 dermally; LC50 (4-hr inhalation): >4.2 mg/ml (Veenstra, Owen)

Dimethomorph price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich CRM56585 Dimethomorph Mixture of E + Z isomers, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland 110488-70-5 100 mg $174 2026-04-30 Buy
Sigma-Aldrich 46027 Dimethomorph mixture of E + Z isomers 110488-70-5 100mg $111 2026-04-30 Buy
Cayman Chemical 24247 Dimethomorph ≥95%(mixtureofcisandtransisomers) 110488-70-5 50mg $49 2026-04-30 Buy
Cayman Chemical 24247 Dimethomorph ≥95%(mixtureofcisandtransisomers) 110488-70-5 100mg $82 2026-04-30 Buy
Cayman Chemical 24247 Dimethomorph ≥95% 110488-70-5 50mg $44 2024-03-01 Buy
Product number Packaging Price Buy
CRM56585 100 mg $174 Buy
46027 100mg $111 Buy
24247 50mg $49 Buy
24247 100mg $82 Buy
24247 50mg $44 Buy

Dimethomorph Chemical Properties,Uses,Production

Description

Dimethomorph is a cinnamic acid derivative and a member of the morpholine chemical family. Dimethomorph is a mixture of E- and Z-isomers in the ratio of about 1:1 and only the Z-isomer has the fungicidal activity. It fungicidal activity works by the inhibition of sterol (ergosterol) synthesis.
Dimethomorph is a systemic fungicide to protect against various fungal pathogens in vines and other crops. Dimethomorph is used to against downy mildews, late blights, anthracnose, septoria leaf spot, crown rot, and root rot for curbubits, grapevines, head lettuce, onions, potatoes, tomatoes, and fruit including blackberries, raspberries, strawberries.

References

[1] http://www.fao.org
[2] http://pmep.cce.cornell.edu
[3] http://sitem.herts.ac.uk/aeru/ppdb/en/Reports/245.htm

Description

Dimethomorph is a morpholine fungicide that inhibits fungal cell wall formation. It inhibits mycelial growth of the oomycete fungi P. citrophthora, P. parasitica, P. capsici, and P. infestans (EC50s = 0.14, 0.38, <0.1, and 0.16-0.3 μg/ml, respectively) but is less active against the green algae species C. vulgaris or S. obliquus in vitro (EC50s = 47.46 and 44.87 μg/ml, respectively). It inhibits androgen receptor (AR) activity in a reporter assay in MDA-kb2 human breast cancer cells but not in a yeast antiandrogen screen (IC20s = 0.263 and 38.5 μM, respectively). It is not toxic to rats (LD50 = 3,900 mg/kg) or goldfish (C. auratus; LC50 = >32 μg/ml).

Chemical Properties

Off-White Solid

Uses

Agricultural fungicide.

Uses

Dimethomorph is a systemic fungicide which exhibits protectant, curative and antisporulant activities. It is active against fungal diseases such as leaf blight, downy mildew, damping off and foot-rot caused by Phytophthora spp. in/on grapes, potatoes and tomatoes.

Definition

ChEBI: A mixture of (E)- and (Z)-dimethomorph in an unspecified ratio. It is used as a systemic fungicide used on vines, potatoes, and greenhouse crops; only the Z isomer has fungicidal activity.

Agricultural Uses

Fungicide: A systemic fungicide that protects crops from mold. It also kills mold and prevents their spread; controls late blight on tomatoes; and is used as a wood preservative to control downey mildew.

Trade name

ACROBAT® WP; FORUM DC®, [manco- zeb + dimethomorph]; CME 151®; STATURE®

Synthesis

The first step: xylene and acetic anhydride at room temperature stirring drop of morpholine, drop the end of the slow increase in temperature to 110 , reflux insulation 5h, after the end of the over into the distillation kettle desolvation and by-products of acetic acid, the kettle residual part for the intermediate acetyl morpholine The residual part in the kettle is the intermediate acetylmorpholine, the content is more than or equal to 99%, the yield is more than or equal to 90.2%.
The second step: in the reaction kettle into xylene, E-phenyl ketone and amino sodium, stirring temperature to 100 when adding acetomorpholine drops, droplet finished temperature to 110 reflux insulation 2h, insulation end of the temperature to 80 over the wash kettle divided into Out of the waste lye, after washing to neutral water into the distillation kettle recovery of xylene, centrifugal drying enoymorpholine, content greater than or equal to 95%, yield greater than or equal to 76.6%.
In this method, sodium amide is used to replace sodium tert-butoxide in traditional technology, which greatly improves the reaction speed, shortens the reaction time from 10h to 2h, and greatly improves the production efficiency.

Metabolic pathway

Limited data are available in the open literature. Information presented in this summary is abstracted from the data evaluation published by the Pesticide Safety Directorate (PSD, 1994). Dimethomorph is a (1:l) mixture of the E- and Z-isomers. The Z-isomer has been shown to have all the intrinsic biological activities. The isomerisation of the E- and Z-isomers was observed when resolved isomers were exposed to UV light. Dimethomorph undergoes extensive degradation and metabolism in soil, plants and animals. The major metabolic pathway is the O-demethylation of one of the phenolic methoxy moieties to the corresponding phenols and conjugates. Other metabolic reactions include the oxidation of one of the CH2 moieties of the morpholine ring and the cleavage/opening of the morpholine ring (Scheme 1).

Degradation

Dimethomorph (1) is hydrolytically stable with no observable degradation in pH 4-9 buffered solutions at 70-90 °C for up to 10 weeks.
Degradation occurred when dimethomorph in pH 5 buffer solution was irradiated under Hanau Suntest apparatus (<290 nm) at 25 °C. The calculated aqueous photolytic degradation half-life (DT50) was ca. 25-28 days of continuous irradiation, No sigruficant degradation product (>7% of the applied radioactivity) was identified.

References

[1] (EFSA) E F S A. Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethoate[C]//4 7. 2006. DOI: 10.2903/j.efsa.2006.84r
[2] M E MATHERON  M P. Impact of Azoxystrobin, Dimethomorph, Fluazinam, Fosetyl-Al, and Metalaxyl on Growth, Sporulation, and Zoospore Cyst Germination of Three Phytophthora spp.[J]. Plant disease, 2000, 84 4: 454-458. DOI: 10.1094/pdis.2000.84.4.454
[3] XIAO-BO YU. Aquatic environmental safety assessment and inhibition mechanism of chemicals for targeting Microcystis aeruginosa.[J]. Ecotoxicology, 2014, 23 9: 1638-1647. DOI: 10.1007/s10646-014-1303-x

Dimethomorph Preparation Products And Raw materials

Raw materials

Preparation Products

Mancozeb+Dimethomorph,W.P.

Dimethomorph Suppliers

Global( 288)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Qingdao Trust Agri Chemical Co.,Ltd 		+86-008615963231493 +86-008613573296305 trustagri@hotmail.com China 299 58
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 deasea125996@gmail.com China 2472 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 3692 58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD 		+86-15350851019; +8615350851019 admin@86-ss.com China 999 58
Hefei Lbao Physical & Chemical Science Co.,Ltd 		+15184799099 lbaochemicals@gmail.com China 671 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21590 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29819 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Qingdao Trust Agri Chemical Co.,Ltd 		58
Henan Bao Enluo International TradeCo.，LTD 		58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD 		58
Hefei Lbao Physical & Chemical Science Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
Accela ChemBio Inc. 		58
BOC Sciences 		58

Related articles

View Lastest Price from Dimethomorph manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Dimethomorph pictures 2026-05-01 Dimethomorph
110488-70-5
 US $0.00 / kg 1kg 98% Customise Hefei Lbao Physical & Chemical Science Co.,Ltd
Dimethomorph pictures 2026-04-30 Dimethomorph
110488-70-5
 US $1000.00-400.00 / kg 1kg 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Dimethomorph pictures 2026-04-17 Dimethomorph
110488-70-5
 US $0.00 / kg 1kg 98 1000 Qingdao Trust Agri Chemical Co.,Ltd
  • Dimethomorph pictures
  • Dimethomorph
    110488-70-5
  • US $0.00 / kg
  • 98%
  • Hefei Lbao Physical & Chemical Science Co.,Ltd
  • Dimethomorph pictures
  • Dimethomorph
    110488-70-5
  • US $1000.00-400.00 / kg
  • 99%
  • HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
  • Dimethomorph pictures
  • Dimethomorph
    110488-70-5
  • US $0.00 / kg
  • 98
  • Qingdao Trust Agri Chemical Co.,Ltd

Dimethomorph Spectrum

Dimethomorph(110488-70-5)1HNMR

110488-70-5(Dimethomorph)Related Search:

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4-Acryloylmorpholine morpholine 4-Cyclododecyl-2,6-dimethylmorpholine acetate 1-(1-(4-CHLOROPHENYL)VINYL)BENZENE Dimethomorph
Dimethomorph,water-dispersion granule Z-DIMETHOMORPH SOLUTION 100UG/ML IN METHANOL 1ML 4-(3,3-Diphenylallyl)morpholine hydrochloride

1of4

Dimethomorph W.P.(50%) Festival C Dimethomorph 100mg [110488-70-5] Dimethomorph 0 (e,z)-4-[3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl]morpholine (e,z)-4-[3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)acryloyl]morpholine 4-(3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)-morpholin AcrobatWP ACROBAT Morpholine, 4-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl- dimethomorph (bsi, draft-iso) 4-[3-(4-CHLOROPHENYL)-3-(3,4-DIMETHOXYPHENYL)-1-OXO-2-PROPENYL]-MORPHOLINE 4-[3-(4-Chlorophenyl)-3-(3,4-dimethoxyphenyl)acryloyl]morpholine CME 151 DIMETHOMORPH FORUM Dimethomorph{(E,Z)-4-[3-(4-Chlorophenyl)-3-(3,4-Dimethoxphenyl)Acryloy]Morpholine Dimethoroph DIMETHOMORPH MIXTURE OF E + Z ISOMERS, P Factory hot sell Dimethomorph CAS:110488-70-5 with best price Dimethomorph（mixture of E + Z isomers） Acrobat(TM) Dimethomorph +Ametoctradin Dimethomorph in Methanol Dimethomorph Solution in Acetonitrile (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholinoprop-2-en-1-one Dimethomorph Solution, 1000ppm DimethomorphSolution,1000mg/L,1ml DimethomorphSolution,100mg/L,5x1ml DimethomorphSolution,100mg/L,1ml Dimethomorph (E, Z)@1000 μg/mL in Acetonitrile Dimethomorph @100 μg/mL in MeOH Dimethomorph 50%WP Chemical Fungicides Products 110488-70-5 White powder Chemical Pesticide Dimethomorph Fungicide 50%WP 110488-70-5 imethomorph Dimethomorph (0.1 mg/mL in Acetonitrile) Acroyl]-Dimethomorph 13C 3-(4-Chlorophenyl)-3-(3,4-diMethoxyphenyl)-1-(4-Morpholinyl)-2-propen-1-one 3-(4-Chlorophenyl)-3-(3,4-diMethoxyphenyl)-1-Morpholinoprop-2-en-1-one dimethomoph 4-(3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)-morpholin (e,z)-4-[3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl]morpholine (e,z)-4-[3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)acryloyl]morpholine 4-(3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)morpholine Z-DIMETHOMORPH 2-Propen-1-one, 3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-(4-morpholinyl)- Enoylmorpholine technical Dimethomorph in Acetone C12710000 Dimethomorph Dimethomorph 10 μg/ml Ethyl acetate Dimethomorph 10.0 μg/ml Acetonitrile Dimethomorph 100 μg/ml Ethyl acetate L12710000ALDimethomorph 10μg/mLin Acetonitri L12710000CY Dimethomorph 10μg/mLin Cyclohexan Dimethomorph in Acetonitrile dimethomorph (ISO) CAS:110488-70-5 Dimethomorph(mixture of isomer) Dimethomorph 10 μg/mL in Acetonitrile Dimethomorph 10 μg/mL in Cyclohexane 80%Dimethomorph