Hydroxysafflor yellow A
- CAS No.
- 78281-02-4
- Chemical Name:
- Hydroxysafflor yellow A
- Synonyms
- HSYA;SAFFLOMIN A;Hydroxysafflor yellow;Hydroxysafflor yellow A;Hydroxy safflower yellow pigment A;Hydroxylsafflower yellow pigment A;Hydroxysafflor yellow A,Safflomin A;Hydroxysafflor yellow A,SaffloMin A,HSYA;Safflomin A, 98%, from Carthamus tinctorius L.;2,5-Cyclohexadien-1-one, 2,4-di-beta-D-glucopyranosyl-3,4,5-trihydroxy-6-((2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl)-
- CBNumber:
- CB9843710
- Molecular Formula:
- C27H32O16
- Molecular Weight:
- 612.54
- MDL Number:
- MFCD08435942
- MOL File:
- 78281-02-4.mol
| Melting point | 184-186 °C |
|---|---|
| Boiling point | 1015.8±65.0 °C(Predicted) |
| Density | 1.851±0.06 g/cm3(Predicted) |
| solubility | DMF: 1 mg/ml; DMSO: 1 mg/ml; PBS (pH 7.2): 1 mg/ml |
| pka | 4.50±1.00(Predicted) |
| form | powder |
| color | Yellow-orange |
| LogP | 1.688 (est) |
| FDA UNII | HI7O919OYZ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H317 |
| Precautionary statements | P305+P351+P338-P280 |
| Safety Statements | 24/25 |
| HS Code | 29389090 |
Hydroxysafflor yellow A price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 300905 | Safflomin A | 78281-02-4 | 20mg | $405 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb259580 | Safflomin A 98% | 78281-02-4 | 20mg | $408 | 2021-12-16 | Buy |
| Matrix Scientific | 097908 | Hydroxysafflor yellow A 95+% | 78281-02-4 | 250mg | $431 | 2021-12-16 | Buy |
| Biosynth Carbosynth | OH08134 | Hydroxysafflor yellow A | 78281-02-4 | 10mg | $75 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb259580 | Safflomin A 98% | 78281-02-4 | 100mg | $472.6 | 2021-12-16 | Buy |
Hydroxysafflor yellow A Chemical Properties,Uses,Production
Definition
ChEBI: Hydroxysafflor yellow A is a C-glycosyl compound that is 3,4,5-trihydroxycyclohexa-2,5-dien-1-one which is substituted by beta-D-glucosyl groups at positions 2 and 4, and by a p-hydroxycinnamoyl group at position 6. It is the main bioactive compound of a traditional Chinese medicine obtained from safflower (Carthamus tinctorius). It has a role as an anti-inflammatory agent, an antioxidant, a platelet aggregation inhibitor, an antineoplastic agent, a radical scavenger, an EC 3.2.1.48 (sucrose alpha-glucosidase) inhibitor, a neuroprotective agent and a plant metabolite. It is a C-glycosyl compound, a member of phenols, an enone and an enol.
Biological Activity
Hydroxysafflor yellow A is a pigment that has been found in C. tinctorius and has diverse biological activities. It inhibits LPS-induced increases in NF-κB levels and production of nitric oxide (NO), IL-1β, and TNF-α in primary mouse embryonic mesencephalic cultures when used at concentrations of 40 and 160 μM.
in vivo
Hydroxysafflor yellow A (1 and 3 mg/kg) decreases mean arterial pressure (MAP) and heart rate in anesthetized normotensive or spontaneously hypertensive rats. It reduces infarct volume and serum superoxide dismutase (SOD) activity in a rat model of focal transient cerebral is chemia induced by middle cerebral artery occlusion (MCAO) when administered at doses of 2, 4, and 8 mg/kg.
Hydroxysafflor yellow A Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from Hydroxysafflor yellow A manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-24 | Hydroxysafflor yellow A
78281-02-4
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2019-07-14 | SAFFLOMIN A
78281-02-4
|
US $1.00 / KG | 1KG | 99% | 25kg | Career Henan Chemical Co |
-
- Hydroxysafflor yellow A
78281-02-4
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- SAFFLOMIN A
78281-02-4
- US $1.00 / KG
- 99%
- Career Henan Chemical Co