ChemicalBook >> CAS DataBase List >>ZK 200775
ZK 200775
- CAS No.
- 161605-73-8
- Chemical Name:
- ZK 200775
- Synonyms
- MPQX;Fanapanel;ZK 200775;Fanapanel(ZK200775);MPQX;ZK200775;ZK-200775;7-Morpholino-2,3-dioxo-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinoxalin-1-ylmethylphosphonic acid;[[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonicacid;[[3,4-DIHYDRO-7-(4-MORPHOLINYL)-2,3-DIOXO-6-(TRIFLUOROMETHYL)-1(2H)-QUINOXALINYL]METHYL]PHOSPHONIC ACID;P-[[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonic acid;Phosphonic acid, P-[[3,4-dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]-
- CBNumber:
- CB9848467
- Molecular Formula:
- C14H15F3N3O6P
- Molecular Weight:
- 409.25
- MDL Number:
- MFCD07364000
- MOL File:
- 161605-73-8.mol
Last updated:2023-06-30 15:45:59
| Density | 1.615±0.06 g/cm3(Predicted) |
|---|---|
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO: ≥20mg/mL |
| pka | 2.09±0.10(Predicted) |
| form | powder |
| color | off-white to light brown |
| FDA UNII | E3AP71EM0O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H302+H312+H332-H315 |
| Precautionary statements | P280-P301+P312-P305+P351+P338 |
| WGK Germany | 3 |
| HS Code | 2934999090 |
ZK 200775 price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 2345 | ZK200775 ≥99%(HPLC) | 161605-73-8 | 10 | $223 | 2021-12-16 | Buy |
| Tocris | 2345 | ZK200775 ≥99%(HPLC) | 161605-73-8 | 50 | $934 | 2021-12-16 | Buy |
| Usbiological | 257170 | ZK 200775 | 161605-73-8 | 10mg | $502 | 2021-12-16 | Buy |
| TRC | Z485903 | ZK200775(Fanapanel) | 161605-73-8 | 1mg | $85 | 2021-12-16 | Buy |
| TRC | Z485903 | ZK200775(Fanapanel) | 161605-73-8 | 2.5mg | $165 | 2021-12-16 | Buy |
ZK 200775 Chemical Properties,Uses,Production
Uses
ZK 200775 is a competitive AMPA/kainate antagonist. Neuronal protection against cerebral ischemia.
Biological Activity
Competitive AMPA/kainate antagonist. In rat cortical membranes, displays high affinity for [ 3 H]-AMPA (K i = 120 nM) and [ 3 H]-CNQX (K i = 32 nM) binding sites and low affinity for kainate and NMDA channel-associated binding sites (IC 50 values range from 2.5 to 11 μ M). Inhibits currents induced by AMPA, kainate and NMDA with IC 50 values of 21 nM, 27 nM, and > 1 μ M respectively. Displays anxiolytic, anticonvulsant and muscle relaxant activity in vivo .
storage
Desiccate at +4°C
ZK 200775 Preparation Products And Raw materials
Raw materials
Preparation Products
ZK 200775 Suppliers
Global( 52)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 | |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12338 | 58 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7553 | 61 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| ShangHai KenEn Chemical Technology Co., Ltd. | 13120367189 | mychess007@163.com | China | 1994 | 55 |
161605-73-8(ZK 200775)Related Search:
ZK 200775
[[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonicacid
Fanapanel
MPQX
7-Morpholino-2,3-dioxo-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinoxalin-1-ylmethylphosphonic acid
[[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]-phosphonic acid hydrate
P-[[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonic acid
[[3,4-DIHYDRO-7-(4-MORPHOLINYL)-2,3-DIOXO-6-(TRIFLUOROMETHYL)-1(2H)-QUINOXALINYL]METHYL]PHOSPHONIC ACID
Phosphonic acid, P-[[3,4-dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]-
MPQX;ZK200775;ZK-200775
Fanapanel(ZK200775)
161605-73-8
C14H15F3N3O6P
C14H15N3O6F3P