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4-Chlorotoluene

4-Chlorotoluene structure

CAS No.: 106-43-4

Chemical Name:: 4-Chlorotoluene

Synonyms: 1-CHLORO-4-METHYLBENZENE;P-CHLOROTOLUENE;chlorotoluenes;1-chloro-4-methyl-benzen;4-CHLORO-1-METHYLBENZENE;UPD;p-ChL;p-Chlortoluol;4-Chlortoluol;4-Chlorotoluen

CBNumber:: CB9852675

Molecular Formula:: C7H7Cl

Molecular Weight:: 126.58

MDL Number:: MFCD00000631

MOL File:: 106-43-4.mol

MSDS File:: SDS

Last updated:2024-01-26 15:56:36

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4-Chlorotoluene Properties

Melting point	6-8 °C(lit.)
Boiling point	162 °C(lit.)
Density	1.07 g/mL at 25 °C(lit.)
vapor density	4.38 (vs air)
vapor pressure	10 mm Hg ( 45 °C)
refractive index	n20/D 1.52(lit.)
Flash point	121 °F
storage temp.	2-8°C
solubility	0.040g/l
form	Liquid
color	Clear
PH	7.4 (H2O)(saturated aqueous solution)
explosive limit	0.7-12.2%(V)
Water Solubility	<0.1 g/100 mL at 20 ºC
Merck	14,2171
BRN	1903635
Dielectric constant	6.0800000000000001
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
LogP	3.33 at 20℃
CAS DataBase Reference	106-43-4(CAS DataBase Reference)
EWG's Food Scores	1
NCI Dictionary of Cancer Terms	PCT
FDA UNII	Q8R236H42N
NIST Chemistry Reference	Benzene, 1-chloro-4-methyl-(106-43-4)
EPA Substance Registry System	p-Chlorotoluene (106-43-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07,GHS09

Signal word

Warning

Hazard statements

H226-H317-H332-H411

Precautionary statements

P210-P233-P273-P280-P303+P361+P353-P304+P340+P312

Hazard Codes

Xn,N,T,F

Risk Statements

20-51/53-39/23/24/25-23/24/25-11-10-43

Safety Statements

24/25-61-45-36/37-16-7

RIDADR

UN 2238 3/PG 3

WGK Germany

RTECS

XS9010000

Hazard Note

Harmful

TSCA

Yes

HazardClass

PackingGroup

III

HS Code

29036990

HS Code

29337900

NFPA 704

	2
2		0

4-Chlorotoluene price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	111929	4-Chlorotoluene 98%	106-43-4	100g	$107	2024-03-01	Buy
Sigma-Aldrich	111929	4-Chlorotoluene 98%	106-43-4	500g	$260	2024-03-01	Buy
Sigma-Aldrich	SAB2502168	Anti-UROD antibody produced in goat affinity isolated antibody, buffered aqueous solution	106-43-4	100μG	$545	2023-01-07	Buy
TCI Chemical	C0297	4-Chlorotoluene	106-43-4	25G	$28	2024-03-01	Buy
TCI Chemical	C0297	4-Chlorotoluene	106-43-4	500G	$72	2024-03-01	Buy

Product number	Packaging	Price	Buy
111929	100g	$107	Buy
111929	500g	$260	Buy
SAB2502168	100μG	$545	Buy
C0297	25G	$28	Buy
C0297	500G	$72	Buy

4-Chlorotoluene Chemical Properties,Uses,Production

Chemical Properties

Colorless oily liquid. Slightly soluble in water. Soluble in ethanol, ether, acetone, benzene and chloroform.

Uses

4-Chlorotoluene is used in a variety of organic synthesis, such as acting as coupling precursors for palladium-catalyzed acylation of acetanilides. It is also used for the preparation model gas of 4-chlorotoulene by passing synthesized air into liquid 4-chlorotoulene.

Application

4-chlorotoluene is used as a solvent and intermediate for dyes and other organic chemicals. It is used mainly to produce p-chlorobenzotrichloride, from whichis obtained p-chlorobenzotrifluoride, an important precursor of herbicides (e.g., trifluralin:α,α,α,-trifluoro-2,6-dinitro-N,Ndipropyl-p-toluidine). Other side-chain-chlorinated products or their derivatives are 4- chlorobenzyl chloride (for pharmaceuticals, rice herbicides, and pyrethrin insecticides), 4- chlorobenzaldehyde (for dyes and pharmaceuticals), 4-chlorobenzoyl chloride (for pharmaceuticals and peroxides), and 4-chlorobenzoic acid (for dyes). 4-Chlorotoluene is also a starting material in the synthesis of 2,4- and 3,4-dichlorotoluene and of 4-chlorobenzonitrile. [ChemicalBook]

Definition

ChEBI: 4-Chlorotoluene is a member of monochlorobenzenes. It is an intermediate for the manufacture of Fenvalerate, Paclobutrazol, Uniconazole, Trifluralin,Thiobencarb, Daimuron and other pesticides.

Preparation

4-Chlorotoluene is obtained from p-toluidine by diazotization and substitution. Add p-toluidine and hydrochloric acid to the reaction pot and stir and heat until dissolved at 60℃, then cool to below 15℃ and add sodium nitrite solution dropwise. After reaching the end point, continue to stir for 0.5h. Add cuprous chloride hydrochloric acid solution and stir at room temperature for 3h. Then raise the temperature to 60℃ and keep for 0.5h, cool to room temperature and leave to stratify, discard the acid water layer, wash with water to neutral, filter and get p-chlorotoluene.

General Description

The reaction of 4-chlorotouleneand phenylboronic acid with Pd(OAc)2/L?2HX as the catalyst is the model reaction for determining the efficiencies of bisimidazolylidene (L) ligand precursors.

Hazard

Avoid inhalation; strong irritant.

Flammability and Explosibility

Flammable

Safety Profile

Moderately toxic by ingestion. Mdly toxic by inhalation. Flammable when exposed to heat or flame. When heated to decomposition it emits toxic fumes of Cl-. See also TOLYL CHLORIDE and CHLORINATED HYDROCARBONS, AROMATIC.

Purification Methods

Dry it with BaO, fractionally distil it, then fractionally crystallise it by partial freezing. [Beilstein 5 IV 806.]

4-Chlorotoluene Preparation Products And Raw materials

Raw materials

Toluene Chlorine Industrial hydrochloric acid Ferric chloride Copper(I) chloride

Copper(II) sulfate Monochlorotoluene p-Toluidine 2-Chlorotoluene Sodium metabisulfite

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Preparation Products

1-[2-(4-CHLOROPHENYL)-1-(1-HYDROXY-1-PHENYLETHYL)ETHYL]-1,2,4-TRIAZOLE 2-Chlorobenzotrichloride 4-Chlorobenzotrichloride 4-Chlorobenzaldehyde 2,4-Dichlorobenzotrifluoride

2,4-Dichlorotoluene 4-Chlorobenzyl cyanide 2-(4-Chlorophenyl)-3-methylbutyric acid 3,4-Dichlorobenzotrifluoride Cyfluthrin

FLUORODIFEN 4-Chlorobenzoic acid 2-Methoxy-5-methylaniline 4-Fluorobenzaldehyde 5-chloro-2-methylbenzenediazonium

brofenvalerate 4-chloro-1-(dichloromethyl)benzene 4-Chlorobenzyl chloride Fomesafen 4-Fluoro-3-phenoxybenzaldehyde

4-Chlorobenzotrifluoride

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4-Chlorotoluene Suppliers

Global( 381)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Xin Cheng Yue Chemical Co.,Ltd	+86-021-57806787 +86-17701820076	wuziwei@xinyuefirm.com	China	30	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7845	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1807	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2931	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2967	58

Supplier	Advantage
Shanghai Xin Cheng Yue Chemical Co.,Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Time Chemicals CO., Ltd.	55
career henan chemical co	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58
Hubei Jusheng Technology Co.,Ltd.	58
Jinan Finer Chemical Co., Ltd	58

View Lastest Price from 4-Chlorotoluene manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-26	4-Chlorotoluene 106-43-4	US $1.00 / KG	1KG	99.5%	1000mt/year	Jinan Finer Chemical Co., Ltd
2024-04-25	4-Chlorotoluene 106-43-4	US $0.00-0.00 / kg	1000kg	99.8%	100000ton	Shanghai Xin Cheng Yue Chemical Co.,Ltd
2023-12-26	4-Chlorotoluene 106-43-4	US $100.00-1.00 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd

4-Chlorotoluene
106-43-4
US $1.00 / KG
99.5%
Jinan Finer Chemical Co., Ltd

4-Chlorotoluene
106-43-4
US $0.00-0.00 / kg
99.8%
Shanghai Xin Cheng Yue Chemical Co.,Ltd

4-Chlorotoluene
106-43-4
US $100.00-1.00 / KG
99%
Henan Fengda Chemical Co., Ltd

4-Chlorotoluene Spectrum

4-Chlorotoluene(106-43-4)MS 4-Chlorotoluene(106-43-4)¹HNMR 4-Chlorotoluene(106-43-4)IR1 4-Chlorotoluene(106-43-4)IR2 4-Chlorotoluene(106-43-4)Raman

106-43-4(4-Chlorotoluene)Related Search:

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Methyl salicylate Kresoxim-methyl Thiophanate-methyl Xylene Tosyl chloride

p-Toluenesulfonamide Methyl à-chlorotoluene TRITON alpha,alpha,alpha-trichloro-4-chlorotoluene

1,2-CHLOROTOLUENE,O-CHLOROTOLUENE,REAGENT,2-Chlorotoluene 99%,2-Chlorotoluene,99% Methyl bromide Difluorochloromethane

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1-Methyl-4-chlorobenzene 4-CHLOROTOLUENE 4-Chlorotoluene p-Chlorotoluene 4-Chlortoluol 4-Methylphenylchloride 4-Tolylchloride p-Chlortoluol p-Methylchlorobenzene p-Tolyl chloride p-tolylchloride Toluene, p-chloro- toluene,4-chloro- toluene,p-chloro Toluene,p-chloro- 4-CHLOROTOLUENE, 1000MG, NEAT 4-CHLOROTOLUENE PESTANAL 4-Chlorotoluene,>99% 4-CHLOROTOLUENE / 4-CHLORO-1-METHYLBENZENE 4-Chlorotoluene (1mg/ml in Methanol) [for Water Analysis] UPD Chlorine toluene 4-methyl-chlorobenzene OTTHUMP00000010502 OTTHUMP00000010503 4-Chlorotoluene solution p-chlorot01uene 4-Chlorotoluene 5g [106-43-4] 4-Chlorotoluene 10g [106-43-4] 4-Chlorotoluene 4-Chlorotoluene, 98% 1LT Benzene,1-chloro-4-methyl- chloro-4toluene para-Chlorotoluene p-Chloromethylbenzene p-chloro-toluen Chlorotoluene, 4-: (p-Tolyl chloride) p-CHLOROTOLUENE pure 4-Chlorotoluene,98% p-Chlorotoluene solution p-Chlorotoluene Standard AKOS BBS-00004363 4-Chlorotoluen 4-Chlorotoluene 106-43-4 p-ChL 4-ChlorotolueneSolution,5,000mg/L,1ml 4-Chlorotoluene > 4-ChlorotolueneSolution,2,000mg/L,1ml 4-chlorotoluene Solution, 100μg/mL 4-Chlorotoluene ISO 9001：2015 REACH 4-Chlorotoluene PCT 1-chloro-4-methyl-benzen 1-CHLORO-4-METHYLBENZENE 4-CHLORO-1-METHYLBENZENE P-CHLOROTOLUENE chlorotoluenes Anti-UROD antibody produced in goat Benzyl Alcohol Impurity H Para Chloro toluene (PCT)