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Diethyl succinate

CAS No.
123-25-1
Chemical Name:
Diethyl succinate
Synonyms
diethyl butanedioate;Clorius;ETHYL SUCCINATE;BUTANEDIOIC ACID DIETHYL ESTER;SUCCINIC ACID DIETHYL ESTER;FEMA 2377;Diethylester kyseliny jantarove;Diethyl ester of butanedioic acid;Diethyl succite;Diethylsuccinat
CBNumber:
CB9852963
Molecular Formula:
C8H14O4
Molecular Weight:
174.19
MDL Number:
MFCD00009208
MOL File:
123-25-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 12:01:10
Product description Number Pack Size Price
Diethyl succinate natural, ≥99%, FG W237712 1 each $61.1
Diethyl succinate natural, ≥99%, FG W237712 100g $65.4
Diethyl succinate natural, ≥99%, FG W237712 1kg $221
Diethyl succinate natural, ≥99%, FG W237712 5kg $977
Diethyl succinate ≥99%, FCC, FG W237701 1 each $59.8
More product size

Diethyl succinate Properties

Melting point -20 °C (lit.)
Boiling point 218 °C (lit.)
Density 1.047 g/mL at 25 °C (lit.)
vapor density 6 (vs air)
vapor pressure 1.33 hPa (55 °C)
FEMA 2377 | DIETHYL SUCCINATE
refractive index n20/D 1.42(lit.)
FLAVIS Number 09.444 | Diethyl succinate
Flash point 195 °F
storage temp. Store below +30°C.
solubility 2.00g/l
form Liquid
color Clear colorless to yellow
Odor at 100.00 %. mild fruity cooked apple ylang
Odor Type fruity
biological source synthetic
Viscosity 2.685mm2/s
Water Solubility Slightly soluble in water.
Merck 14,8869
JECFA Number 617
BRN 907645
Henry's Law Constant 1.9×101 mol/(m3Pa) at 25℃, Duchowicz et al. (2020)
Dielectric constant 6.6(30℃)
Cosmetics Ingredients Functions FRAGRANCE
SOLVENT
SKIN CONDITIONING - EMOLLIENT
PLASTICISER
Cosmetic Ingredient Review (CIR) Diethyl succinate (123-25-1)
InChI 1S/C8H14O4/c1-3-11-7(9)5-6-8(10)12-4-2/h3-6H2,1-2H3
InChIKey DKMROQRQHGEIOW-UHFFFAOYSA-N
SMILES CCOC(=O)CCC(=O)OCC
LogP 1.4 at 40℃
CAS DataBase Reference 123-25-1(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) DIETHYL SUCCINATE
FDA 21 CFR 172.515
EWG's Food Scores 1
FDA UNII ELP55C13DR
NIST Chemistry Reference Diethyl succinate(123-25-1)
EPA Substance Registry System Butanedioic acid, 1,4-diethyl ester (123-25-1)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H227
Precautionary statements  P210e-P280a-P370+P378a-P403+P235-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25-22-S24/25
WGK Germany  2
RTECS  WM7400000
TSCA  TSCA listed
HS Code  29171990
Storage Class 10 - Combustible liquids
Toxicity LD50 orally in Rabbit: 8530 mg/kg LD50 dermal Rat > 5000 mg/kg
NFPA 704
1
0

Diethyl succinate price More Price(57)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W237712 Diethyl succinate natural, ≥99%, FG 123-25-1 1 each $61.1 2026-03-19 Buy
Sigma-Aldrich W237712 Diethyl succinate natural, ≥99%, FG 123-25-1 100g $65.4 2026-03-19 Buy
Sigma-Aldrich W237712 Diethyl succinate natural, ≥99%, FG 123-25-1 1kg $221 2026-03-19 Buy
Sigma-Aldrich W237712 Diethyl succinate natural, ≥99%, FG 123-25-1 5kg $977 2026-03-19 Buy
Sigma-Aldrich W237701 Diethyl succinate ≥99%, FCC, FG 123-25-1 1 each $59.8 2026-03-19 Buy
Product number Packaging Price Buy
W237712 1 each $61.1 Buy
W237712 100g $65.4 Buy
W237712 1kg $221 Buy
W237712 5kg $977 Buy
W237701 1 each $59.8 Buy

Diethyl succinate Chemical Properties,Uses,Production

Description

Diethyl succinate is obtained by the direct esterification of a carboxylic acid and an alcohol in the presence of concentrated H2SO4 in benzene solution. It has a faint, pleasant odor. It occurs naturally in apple, raspberry, cognac, rum, whiskey, cider, sherry, plum brandy, apple brandy, grape brandy, cherry brandy, cocoa, arrack and red, white, port, strawberry and sparking wines.
It is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, frozen dairy, hard/soft candy, gelatins, and puddings.

References

[1] George A. Burdock (2016) Fenaroli’s Hanbook of Flavor Ingredients, Sixth Edition
[2] https://en.wikipedia.org/wiki/Diethyl_succinate

Chemical Properties

Diethyl succinate is the diethyl ester of succinate. It is a colorless liquid with a faint, pleasant odor. miscible with ethanol and ether, soluble in acetone, insoluble in water.

Occurrence

Reported found in apple, raspberry, cognac, rum, whiskey, cider, sherry, plum brandy, apple brandy, grape brandy, cherry brandy, cocoa, arrack and red, white, port, strawberry and sparkling wines.

Uses

Diethyl succinate can be used as solvent; food flavoring agent; organic synthesis intermediate; gas chromatography stationary solution (maximum use temperature 60°C, solvent is ether). Alkyl succinates have been used as ashless dispersants and detergent additives for lubricating oils.

Uses

Diethyl Succinate is a diester molecule present naturally in plant and animal tissues. Used commonly in fragrances and food flavourings.

Preparation

Diethyl succinate is synthesized by esterification of succinic acid and ethanol; by direct esterification of the acid in the presence of concentrated H2SO4 in benzene solution.

Definition

ChEBI: Diethyl succinate is a fatty acid ester.

Aroma threshold values

Aroma characteristics at 1.0%: fruity, waxy, floral and slightly musty.

Taste threshold values

Taste charReported found in apple, raspberry, cognac, rum, whiskey, cider, sherry, plum brandy, apple brandy, grape brandy, cherry brandy, cocoa, arrack and red, white, port, strawberry and sparkling wines. acteristics at 10 to 100 ppm: chemical earthy, fruity with a pulpy mouthfeel

Synthesis Reference(s)

The Journal of Organic Chemistry, 56, p. 6720, 1991 DOI: 10.1021/jo00023a047
Tetrahedron Letters, 28, p. 2393, 1987 DOI: 10.1016/S0040-4039(00)96133-1

General Description

Diethyl succinate(DES) is a diethyl ester with succinate molecules. It has two ester groups and is majorly used in fragrances. It produced by the esterification of succinic acid with ethanol.

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

Taste at 10-100 ppm

Safety Profile

Mildly toxic by ingestion. A skin and eye irritant. Combustible liquid. Reaction with ethyl trifluoroacetate + sodium hydride may cause a fire or explosion. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTERS.

Purification Methods

Dry the succinate with MgSO4, and distil it at 15mm pressure. [Beilstein 2 IV 1914.]

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View Lastest Price from Diethyl succinate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Diethyl succinate pictures 2026-04-24 Diethyl succinate
123-25-1
US $0.00 / KG 25KG 99%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
Diethyl succinate pictures 2026-04-23 Diethyl succinate
123-25-1
US $30.00 / mg 98.00% 10g TargetMol Chemicals Inc.
Diethyl succinate pictures 2026-03-20 Diethyl succinate
123-25-1
US $0.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
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