betazole
- CAS No.
- 105-20-4
- Chemical Name:
- betazole
- Synonyms
- betazole;Ametazole;betazole USP/EP/BP;1H-Pyrazole-3-ethanamine;2-(3-Pyrazolyl)ethanamine;3-(2-Aminoethyl)-1H-pyrazole;2-(1H-pyrazol-5-yl)ethanamine;2-(1H-pyrazol-5-yl)ethan-1-amine;2-(1H-pyrazol-5-yl)ethanamine(SALTDATA: FREE)
- CBNumber:
- CB9898598
- Molecular Formula:
- C5H9N3
- Molecular Weight:
- 111.15
- MDL Number:
- MFCD00867261
- MOL File:
- 105-20-4.mol
- MSDS File:
- SDS
Melting point | 25°C |
---|---|
Boiling point | bp0.5 118-123° |
Density | 0.9902 (rough estimate) |
refractive index | 1.4690 (estimate) |
storage temp. | 4°C, protect from light |
solubility | DMSO: 250 mg/mL (2249.21 mM) |
pka | 14.39±0.10(Predicted) |
FDA UNII | 1C065P542O |
ATC code | V04CG02 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
betazole price More Price(14)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | P847045 | 2-(3-Pyrazolyl)ethanamine | 105-20-4 | 10mg | $45 | 2021-12-16 | Buy |
TRC | P847045 | 2-(3-Pyrazolyl)ethanamine | 105-20-4 | 100mg | $155 | 2021-12-16 | Buy |
ChemScene | CS-0013438 | Betazole 96.86% | 105-20-4 | 10mg | $270 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0009171 | 2-(1H-PYRAZOL-3-YL)-ETHYLAMINE 95.00% | 105-20-4 | 1G | $555.45 | 2021-12-16 | Buy |
ChemScene | CS-0013438 | Betazole 96.86% | 105-20-4 | 50mg | $730 | 2021-12-16 | Buy |
betazole Chemical Properties,Uses,Production
Originator
Histalog,Lilly,US,1953
Definition
ChEBI: Pyrazole in which a hydrogen adjacent to one of the nitrogen atoms is substituted by a 2-aminoethyl group. It is a histamine H2-receptor agonist used clinically to test gastric secretory function.
Manufacturing Process
A solution of 55 grams (1.1 mol) of hydrazine hydrate in 100 ml of methanol was cooled in a water bath and stirred while a solution of 48 grams (0.50 mol) of pure γ-pyrone in 100 ml of methanol was added over a period of about 15 minutes. After the addition was complete, the solution was allowed to stand at room temperature for about 1 hour, and was placed in a 1 liter hydrogenation bomb. 25 ml of liquid ammonia were added cautiously with stirring, followed by about 15 cc of Raney nickel catalyst. The bomb was charged with hydrogen to 1,800 pounds pressure, heated to 90°C and agitated. The quantity of hydrogen required to convert the hydrazone into the desired aminoethylpyrazole was taken up in about 3 hours. The bomb was cooled and opened, and the contents filtered. The filtrate was evaporated under reduced pressure to remove the methanol and the residual liquid was distilled under reduced pressure, whereby there were obtained 44.5 grams (81% yield) of 3-β-aminoethylpyrazole boiling at 118°-123°C at a pressure of 0.5 mm of Hg.
brand name
Histalog (Lilly).
Therapeutic Function
Diagnostic aid (gastric secretion)
betazole Preparation Products And Raw materials
betazole Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9271 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29118 | 58 |
Nanjing Hengbei Chemicals Co., Ltd. | +86-25-58393656 | sales@hengbeichem.cn | China | 6856 | 58 |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12338 | 58 |
Aikon International Limited | 025-66113011 18112977050 | sales01@aikonchem.com | China | 16028 | 58 |
View Lastest Price from betazole manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-08-13 | betazole USP/EP/BP
105-20-4
|
US $1.10 / g | 1g | 0.999 | 100 Tons min | Dideu Industries Group Limited |
- betazole USP/EP/BP
105-20-4
- US $1.10 / g
- 0.999
- Dideu Industries Group Limited
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