ChemicalBook >> CAS DataBase List >>1-methyl-4-phenylpiperidine-4-carbonitrile

1-methyl-4-phenylpiperidine-4-carbonitrile

CAS No.
3627-62-1
Chemical Name:
1-methyl-4-phenylpiperidine-4-carbonitrile
Synonyms
4-CYANO-1-METHYL-4-PHENYLPIPERIDINE;3-Methyl-4-phenyl-4-piperidinenitrile;1-Methyl-4-phenyl-4-piperidinecarbonitrile;1-methyl-4-phenylpiperidine-4-carbonitrile
CBNumber:
CB9910724
Molecular Formula:
C13H16N2
Molecular Weight:
200.28
MDL Number:
MFCD05857352
MOL File:
3627-62-1.mol
Last updated:2023-07-12 17:19:35

1-methyl-4-phenylpiperidine-4-carbonitrile Properties

Melting point 53 °C
Boiling point 148 °C(Press: 4.5 Torr)
Density 1.07±0.1 g/cm3(Predicted)
pka 6.82±0.10(Predicted)
FDA UNII EL4L2474TY

1-methyl-4-phenylpiperidine-4-carbonitrile Chemical Properties,Uses,Production

Chemical Properties

crystallization. Melting point 53 ℃. Boiling point 148/544Pa (4mmHg).

Uses

1-methyl-4-phenylpiperidine-4-carbonitrile can be used as an intermediate in the synthesis of meperidine (Meluidine).

Synthesis

1-methyl-4-phenylpiperidine-4-carbonitrile is prepared by reacting by bis (β-chloroethyl) methylamine hydrochloride and benzyl cyanide condensation in the participation of sodium amide.

1-methyl-4-phenylpiperidine-4-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

1-methyl-4-phenylpiperidine-4-carbonitrile 4-CYANO-1-METHYL-4-PHENYLPIPERIDINE 3-Methyl-4-phenyl-4-piperidinenitrile 1-Methyl-4-phenyl-4-piperidinecarbonitrile 3627-62-1