bamifylline hydrochloride
- CAS No.
- 20684-06-4
- Chemical Name:
- bamifylline hydrochloride
- Synonyms
- AC-3810;Briofil;BAX2793Z;Trentadil;BAX 2793Z;BAX-2793Z;BAMIFYLLINE HCL;BAMIPHYLLINE HCL;BAMIPHYLLINE HCL (GMP);Bamiphyllinehydrochloride
- CBNumber:
- CB9929568
- Molecular Formula:
- C20H27N5O3.ClH
- Molecular Weight:
- 421.926
- MDL Number:
- MOL File:
- 20684-06-4.mol
| Melting point | 185-186° |
|---|---|
| FDA UNII | 66466QLM3S |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| Toxicity | LD50 in mice, rats (mg/kg): 246, 1139 orally; 89, 131 i.p.; 67, 65 i.v. (Georges) |
bamifylline hydrochloride Chemical Properties,Uses,Production
Originator
Bamifylline,ZYF Pharm Chemical
Uses
Bronchodilator.
Manufacturing Process
A mixture of 100 kg of 8-benzyltheophilline, 36 L of N-ethylethanolamine, 300 L of 1,2-dichlorethane and 71 kg of sodium carbonate was refluxed for 24 hours. Then 36 L of N-ethylethanolamine was added and the reaction mixture was refluxed. After cooling to the mixture was added the water and hydrochloric acid. The organic phase was extracted with hydrochloric acid. The acidic phase was neutralized with sodium carbonate and the 7-(N-ethyl-N-β- hydroxyethylaminoethyl)-8-benzyltheophilline was extracted with dichloromethane. The solvent was evaporated and the free base of 7-(N-ethyl- N-β-hydroxyethylaminoethyl)-8-benzyltheophilline was dissolved in methanol. Hydrochloride of 7-(N-ethyl-N-β-hydroxyethylaminoethyl)-8-benzyltheophilline was obtained by addition to the solution the hydrochloric acid; yield 81%, melting point 185-186°C.
Therapeutic Function
Bronchodilator, Coronary vasodilator
bamifylline hydrochloride Preparation Products And Raw materials
bamifylline hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10248 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| Shanghai Synchem Pharma Co., ltd | 021-61984905-1 18016477331 | synchempharma@aliyun.com | China | 6454 | 55 |
| Shanghai Jiegu Biotechnology Co., Ltd. | 021-51698675 | jiejiegroup@126.com | China | 4105 | 58 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-61109150 | sales@tcisct.com | China | 31183 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
| Shaanxi Dideu Newmaterial Co., Ltd. | 029-63373950 15353716720 | 1052@dideu.com | China | 10007 | 58 |
View Lastest Price from bamifylline hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-11 | bamifylline hydrochloride
20684-06-4
|
US $30.00 / kg | 1kg | 99% | 20 tons | Anhui Ruihan Technology Co., Ltd |
-
- bamifylline hydrochloride
20684-06-4
- US $30.00 / kg
- 99%
- Anhui Ruihan Technology Co., Ltd