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CPNQ
- CAS No.
- 115687-05-3
- Chemical Name:
- CPNQ
- Synonyms
- B2;CPNQ;SIRT2-IN-8;SIRT2 Inhibitor, B2;Linazolamide intermediate B impurity 2;5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline;(4-chlorophenyl)-[4-(8-nitroquinolin-5-yl)piperazin-1-yl]methanone;Methanone, (4-chlorophenyl)[4-(8-nitro-5-quinolinyl)-1-piperazinyl]-;Sirtuin,Parkinson’s diseases,Huntington’s diseases,Inhibitor,B2,inhibit,B-2
- CBNumber:
- CB9972382
- Molecular Formula:
- C20H17ClN4O3
- Molecular Weight:
- 396.83
- MDL Number:
- MFCD02039810
- MOL File:
- 115687-05-3.mol
Last updated:2023-09-20 16:43:00
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H315-H319-H335 |
| Precautionary statements | P301+P310+P330-P302+P352-P305+P351+P338 |
| Hazard Codes | T |
| Risk Statements | 25-36/37/38 |
| Safety Statements | 26-45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
CPNQ price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C3118 | CPNQ ≥98% (HPLC), solid | 115687-05-3 | 5mg | $193 | 2024-03-01 | Buy |
| Sigma-Aldrich | C3118 | CPNQ ≥98% (HPLC), solid | 115687-05-3 | 25mg | $719 | 2021-12-16 | Buy |
| TRC | B820015 | B2 | 115687-05-3 | 1mg | $200 | 2021-12-16 | Buy |
| Usbiological | 254701 | B2 | 115687-05-3 | 10mg | $403 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008461 | CPNQ 95.00% | 115687-05-3 | 10MG | $673.08 | 2021-12-16 | Buy |
CPNQ Chemical Properties,Uses,Production
Uses
B2 is a cell permeable inhibitor of SIRT2 (sirtuin 2). Multidrug resistance protein 4 (MRP4) inhibitor in tumors such as neuroblastoma and colorectal cancer.
Definition
ChEBI: (4-chlorophenyl)-[4-(8-nitro-5-quinolinyl)-1-piperazinyl]methanone is a N-arylpiperazine.
Biological Activity
Promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease. Prevents huntingtin-mediated proteasome dysfunction and reduces α -synuclein-mediated toxicity.
CPNQ Preparation Products And Raw materials
Raw materials
Preparation Products
CPNQ Suppliers
Global( 41)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Zhengzhou Guancheng Laboratory equipment Sales | 0371-88888888 272369594 | 2723695949@qq.com | China | 5007 | 50 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3413 | 55 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2987 | 58 |
| Chengdu MassCale Pharmaceutical Co., Ltd. | 028-84552636 18084815636 | chensfsc@126.com | China | 1448 | 58 |
5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline
B2
Linazolamide intermediate B impurity 2
(4-chlorophenyl)-[4-(8-nitroquinolin-5-yl)piperazin-1-yl]methanone
SIRT2 Inhibitor, B2
Methanone, (4-chlorophenyl)[4-(8-nitro-5-quinolinyl)-1-piperazinyl]-
Sirtuin,Parkinson’s diseases,Huntington’s diseases,Inhibitor,B2,inhibit,B-2
SIRT2-IN-8
CPNQ
115687-05-3