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Sodium salicylate

Sodium salicylate
Sodium salicylate structure
CAS No.
54-21-7
Chemical Name:
Sodium salicylate
Synonyms
clin;NASAL;ardall;aroall;alysine;kerosal;nadisal;salisod;diuretin;magsalyl
CBNumber:
CB1255762
Molecular Formula:
C7H5NaO3
Formula Weight:
160.1
MOL File:
54-21-7.mol

Sodium salicylate Properties

Melting point:
>300 °C (lit.)
Density 
0.32 g/cm3 (20℃)
storage temp. 
Store at +15°C to +25°C.
solubility 
1000g/l
form 
Crystals or Crystalline Powder
color 
White
PH
6.5 (100g/l, H2O, 20℃)
Water Solubility 
1000 g/L (20 ºC)
Sensitive 
Light Sensitive
Merck 
14,8332
BRN 
3732792
Stability:
Stable. Incompatible with mineral acids, metallic salts, iodine. May be light-sensitive.
InChIKey
ABBQHOQBGMUPJH-UHFFFAOYSA-M
CAS DataBase Reference
54-21-7(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances
SODIUM SALICYLATE
FDA 21 CFR
175.105; 310.545
EWG's Food Scores
1
FDA UNII
WIQ1H85SYP
NCI Dictionary of Cancer Terms
nasal; sodium salicylate
NCI Drug Dictionary
sodium salicylate
EPA Substance Registry System
Sodium salicylate (54-21-7)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H319-H315-H335
Precautionary statements  P261-P280a-P304+P340-P405-P501a-P301+P312+P330-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-41-36/37/38-36
Safety Statements  26-36
WGK Germany  1
RTECS  VO5075000
8
Autoignition Temperature >250 °C
TSCA  Yes
HS Code  29182100
Toxicity LD50 i.p. in rats: 780 mg/kg (Goldenthal)
NFPA 704
1
2 1

Sodium salicylate price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1.06601 Sodium salicylate for analysis EMSURE? 54-21-7 250 g $84.45 2021-03-22 Buy
Sigma-Aldrich 567630 Sodium Salicylate - CAS 54-21-7 - Calbiochem A cell-permeable, non-steroidal anti-inflammatory agent that interferes with TNF-induced NF-κB activation by inhibiting phosphorylation and subsequent degradation of the IκB-α protein. 54-21-7 5 g $42.36 2021-03-22 Buy
Sigma-Aldrich 31493 Sodium salicylate puriss. p.a., Reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance) 54-21-7 1kg $140 2021-03-22 Buy
Sigma-Aldrich 1.06601 Sodium salicylate for analysis EMSURE? 54-21-7 1 kg $147.07 2021-03-22 Buy
Sigma-Aldrich S0800000 Sodium salicylate European Pharmacopoeia (EP) Reference Standard 54-21-7 $190 2021-03-22 Buy

Sodium salicylate Chemical Properties,Uses,Production

Description

Sodium salicylate is a sodium salt of salicylic acid. It can be prepared from sodium phenolate and carbon dioxide under higher temperature and pressure. Historically, it has been synthesized from methyl salicylate (found in wintergreen plants or the bark of sweet birch tree) by reacting it with an excess of sodium hydroxide and heating it under reflux.

Chemical Properties

Sodium salicylate, HOC6H4COONa, is a shiny, white powder with sweetish taste and mild aromatic aroma that is soluble in water,glycerol, and alcohol.Used in medicine and as a preservative.

Chemical Properties

Sodium salicylate is of the salicylate family and this compound is known to trigger Reye's Syndrome in children and adults, usually following a viral infection such as influenza or chicken pox. Products containing such salicylates should not be given to children under the age of 19.

Uses

keratolytic

Uses

In manufacture of aspirin, methyl salicylate, and other salicylates. Coupling agent for azo dyes. Has been used as food preservative.

Uses

It is used in medicine as an analgesic and antipyretic. Sodium salicylate also acts as non - steroidal anti - inflammatory drug (NSAID), and induces apoptosis in cancer cells and also necrosis. It is also a potential replacement for aspirin for people sensitive to it. It may also be used as a phosphor for the detection of vacuum ultra violet radiation and electrons.

Definition

A salt or ester of salicylic acid.

brand name

Alysine (Marion Merrell Dow).

General Description

Sodium salicylate may be prepared by the reaction, in aqueoussolution, by adding equal molar ratio of salicylic acidand sodium bicarbonate; evaporating to dryness yields thewhite salt. In solution, particularly in the presence of sodiumbicarbonate, the salt will darken on standing. This is the saltof choice for salicylate medication and usually is administeredwith sodium bicarbonate to lessen gastric distress, or itis administered in enteric coated tablets. However, the useof sodium bicarbonate is ill advised, because it decreases theplasma levels of salicylate and increases the excretion offree salicylate in the urine.
Sodium salicylate, even though not as potent as aspirinfor pain relief, also has less GI irritation and is useful for patientswho are hypersensitive to aspirin.

Safety Profile

Experimental poison by subcutaneous route. Moderately toxic to humans by ingestion. Moderately toxic experimentally by ingestion, intraperitoneal, and intravenous routes. An experimental teratogen. Human systemic effects by multiple and unspecified routes: toxic psychosis, excitement, respiratory stimulation, nausea or vomiting, and sweating. Experimental reproductive effects. Mutation data reported. A powerful irritant which affects the central nervous system. Incompatible with ferric salts, mineral acids, iodme, lead acetate, silver nitrate, sodium phosphate powder. When heated to decomposition it emits toxic fumes of Na2O.

Sodium salicylate Preparation Products And Raw materials

Raw materials

Preparation Products


Sodium salicylate Suppliers

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View Lastest Price from Sodium salicylate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-10-19 Sodium Salicylate
54-21-7
US $10.00 / ASSAYS 1ASSAYS 99% 200ton Shanghai Yunao International Trade Co., Ltd
2021-10-14 Sodium Salicylate
54-21-7
US $5.00 / KG 25KG 99%-100.5% 2000 tons Hebei Dongdu Import and Export Co. LTD
2021-09-14 Sodium salicylate
54-21-7
US $180.00 / Kg/Drum 25KG 99% 10000T Baoji Guokang Healthchem co.,ltd

Sodium salicylate Spectrum


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