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ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Aromatic ketones >4-Amino-3,5-dichloroacetophenone

4-Amino-3,5-dichloroacetophenone

4-Amino-3,5-dichloroacetophenone Structure
CAS No.
37148-48-4
Chemical Name:
4-Amino-3,5-dichloroacetophenone
Synonyms
1-(4-amino-3,5-dichlorophenyl)ethan-1-one;1-(4-Amino-3,5-dichlorophenyl)-ethanone, 3,5-Dichloro-4-aminoacetophenone;5-dichlorophenyl)-;TIMTEC-BB SBB003511;3,5-dichloro-4-amino;Clenbuterol EP Impurity C;4-ACETYL-2,6-DICHLOROANILINE;3, 5-dichloro-4-aminophenone;4-Anubi3,5-dichloroacetophenone;4-AMINO-3,5-DICHLOROACETOPHENONE
CBNumber:
CB0423917
Molecular Formula:
C8H7Cl2NO
Molecular Weight:
204.05
MOL File:
37148-48-4.mol
MSDS File:
SDS
Modify Date:
2024/5/16 18:31:40
Request For Quotation

4-Amino-3,5-dichloroacetophenone Properties

Melting point 162-166 °C(lit.)
Boiling point 351.5±42.0 °C(Predicted)
Density 1.2748 (rough estimate)
refractive index 1.5500 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka -1.72±0.10(Predicted)
form Solid
color Light Tan to Brown
InChI InChI=1S/C8H7Cl2NO/c1-4(12)5-2-6(9)8(11)7(10)3-5/h2-3H,11H2,1H3
InChIKey JLPKZJDZXIKSCP-UHFFFAOYSA-N
SMILES C(=O)(C1=CC(Cl)=C(N)C(Cl)=C1)C
CAS DataBase Reference 37148-48-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
HS Code  29223990
NFPA 704
0
2 0

4-Amino-3,5-dichloroacetophenone price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 536148 4′-Amino-3′,5′-dichloroacetophenone 97% 37148-48-4 25G ₹22212.9 2022-06-14 Buy
TCI Chemicals (India) A1967 4'-Amino-3',5'-dichloroacetophenone min. 98.0 % 37148-48-4 5G ₹4400 2022-05-26 Buy
TCI Chemicals (India) A1967 4'-Amino-3',5'-dichloroacetophenone min. 98.0 % 37148-48-4 25G ₹10800 2022-05-26 Buy
Product number Packaging Price Buy
536148 25G ₹22212.9 Buy
A1967 5G ₹4400 Buy
A1967 25G ₹10800 Buy

4-Amino-3,5-dichloroacetophenone Chemical Properties,Uses,Production

Chemical Properties

4-Amino-3,5-dichloroacetophenone is a white to light yellow crystal powder. Insoluble in cold water, slightly soluble in hot water.

Uses

4-Amino-3,5-dichloroacetophenone is used to synthesize the drug Clenbuterol. Clenbuterol is a steroid-like chemical that was initially developed to treat asthma in horses, working by relaxing the airways in the animals'lungs.

Preparation

4-Amino-3,5-dichloroacetophenone was synthesized by chlorination of 4-aminoacetophenone. Add 4-aminoacetophenone and acetic acid (80%) into the reaction pot, stir and dissolve, quickly add chlorine-containing glacial acetic acid solution, the temperature of the addition is 5°C. After the addition is completed, immediately put into ice water to precipitate, filter, and wash with water to obtain the crude product. Recrystallize with ethanol to obtain the finished product of 4-Amino-3,5-dichloroacetophenone.

Application

4-Amino-3,5-dichloroacetophenone has active chemical properties and has been widely used in industrial chemistry, agricultural chemistry, and pharmaceutical chemistry. As a selective oxidant and green coupling reagent, it participates in a variety of oxidation reactions, rearrangement reactions, and amination reactions. In industry, it can also be used as a raw material for the synthesis of drugs, disinfectants, dyes, food seasonings, adhesives, explosives, etc.

4-Amino-3,5-dichloroacetophenone Preparation Products And Raw materials

Raw materials

Acetic acid 4-Aminoacetophenone Acetic anhydride Chlorine Acetyl chloride
2,6-Dichloroaniline 2,4,6-Trichloroaniline
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Preparation Products

4-Amino-3,5-dichlorophenacylbromide 4-AMINO-ALPHA-TERT-BUTYLAMINE-3,5-DICHLOROACETOPHENONE 1-(4-AMINO-3-CHLORO-PHENYL)-ETHANONE Clenbuterol hydrochloride 3,4,5-TRICHLORO-BENZOICACID
3',5'-Dichloroacetophenone
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4-Amino-3,5-dichloroacetophenone Suppliers

Global( 409)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
BASR Fine Chemicals Pvt. Ltd. +91-9848230391 +91-9848230391 Telangana, India 908 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3889 58 Inquiry
OCEAN TRADING CORPORATION +91(22) 24921669 New Delhi, India 6211 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Basr Fine Chemicals Private Limited 08068442227Ext 547 Hyderabad, India 632 58 Inquiry
Reax Chemicals 08048372701Ext 416 Hyderabad, India 4223 58 Inquiry
Supplier Advantage
BASR Fine Chemicals Pvt. Ltd. 58
Pharma Affiliates 58
Clearsynth Labs 58
OCEAN TRADING CORPORATION 58
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
TCI Chemicals (India) Pvt. Ltd. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Basr Fine Chemicals Private Limited 58
Reax Chemicals 58

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1-(4-Amino-3,5-dichloro-phenyl)-2-ethanone 5-AMINO-3,5-DICHLORO ACETOPHENONE 4''-AMINO-3'',5''-DICHLOROACETOPHENONECLENBUTEROL 4-Amino-3,5-dichloroacetophenone,98% 4′-Amino-3′,5′-dichloroacetophenone,1-(4-Amino-3,5-dichlorophenyl)-ethanone, 3,5-Dichloro-4-aminoacetophenone 3,5-dichloro-p-aMino acetophenone 4-AMino-3,5-dichloroacetophenone, 98% 5GR 4'-AMino-3',5'-dichloroacetophenone SynonyMs 4-Acetyl-2,6-dichloroaniline 4'-Amino-3',5'-dichloroacetophenone 97% TIMTEC-BB SBB003511 1-(4-AMINO-3,5-DICHLOROPHENYL)-ETHANONE 4'-AMINO-3',5'-DICHLOROACETOPHENONE 4-AMINO-3,5-DICHLOROACETOPHENONE 4-ACETYL-2,6-DICHLOROANILINE 3,5-DICHLORO-4-AMINOACETOPHENONE Clenbuterol Impurity 3（Clenbuterol EP Impurity C） Clenbuterol EP Impurity C 4-Anubi3,5-dichloroacetophenone 4-Amino-3,5-dichloroacetophenone CAS: 37148-48-4 CAS 37148-48-4 4-Amino-3,5-dichloroacetophenone High Quality 4-Amino-3, 5-Dichloroacetophenone 4'-Amino-3',5'-dichloroacetophenone > Ethanone, 1-(4-amino-3,5-dichlorophenyl)- Bromo-1-Phenyl-Pentan-1-One 2-Bromovalerophenone Yellow Liquid CAS Pharmaceutical Chemical 2-Bromo-4′-Methylpropiophenone 99% Purity 2-Bromo-1-Phenyl-Pentan-1-One 5-dichlorophenyl)- 3,5-dichloro-4-amino 4-Amino-3,5-dichloroacetophenone Basic information 1-(4-Amino-3,5-dichlorphenyl)ethan-1-on 3, 5-dichloro-4-aminophenone 1-(4-amino-3,5-dichlorophenyl)ethan-1-one 1-(4-Amino-3,5-dichlorophenyl)-ethanone, 3,5-Dichloro-4-aminoacetophenone 4'-Amino-3',5'-dichloroacetophenone 37148-48-4 H2NC6H2Cl2COCH3 Organic Building Blocks Ketones C7 to C8 Carbonyl Compounds Building Blocks Chemical Amines Amines Aromatics Aromatic Acetophenones & Derivatives (substituted) (intermediate of leflunomide) 37148-48-4