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BISNORCHOLENALDEHYDE

BISNORCHOLENALDEHYDE Structure
CAS No.
3986-89-8
Chemical Name:
BISNORCHOLENALDEHYDE
Synonyms
BNKY018-PG01;Bisnorcholeldehyde;KETOBISNORALDEHYDE;Bisnorcholenaldehyde;Progesterone Impurity 7;Progesterone Impurity 24;Progesterone EP Impurity I;Didroprogesterone impurity 2;Progesterone EP Impurity I-02;(20S)-20-Formylpregn-4-en-3-one
CBNumber:
CB3670455
Molecular Formula:
C22H32O2
Molecular Weight:
328.49
MOL File:
Mol file
MSDS File:
SDS
Modify Date:
2025/7/4 14:23:31
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BISNORCHOLENALDEHYDE Properties

Melting point 159-160 °C
Boiling point 459.4±14.0 °C(Predicted)
Density 1.07±0.1 g/cm3(Predicted)
solubility Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
InChI InChI=1S/C22H32O2/c1-14(13-23)18-6-7-19-17-5-4-15-12-16(24)8-10-21(15,2)20(17)9-11-22(18,19)3/h12-14,17-20H,4-11H2,1-3H3/t14-,17+,18-,19+,20+,21+,22-/m1/s1
InChIKey XVPJEGGIGJLDQK-HOFZUOGSSA-N
SMILES C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@H]([C@@H](C=O)C)CC3)CC2

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H351-H362-H360
Precautionary statements  P201-P202-P281-P308+P313-P405-P501-P201-P260-P263-P264-P270-P308+P313

BISNORCHOLENALDEHYDE Chemical Properties,Uses,Production

Description

Androstenedione is the main product after phytosterol fermentation by Mycobacteria. Bisnorcholenaldehyde (BA; 3-Oxopregn-4-ene-20-carboxaldehyde) is one of the by-products produced during fermentation. Bisnorcholenaldehyde is an essential intermediate in the production of progesterone, which is used to treat threatened abortion or habitual abortion disease caused by luteal insufficiency. It is a precursor of androgen, estrogen, glucocorticoid and intermediates of steroid hormone synthesis[1]. In addition, BA is used in magnetic-based graphene composites with steroidal diamine dimer as a potential drug in hyperthermia cancer therapy.

Uses

Bisnorcholenaldehyde is hydrocarbon derivatives and can be used as reference materials for medical impurities.

References

[1] Shi-Dong Xu. “Refining androstenedione and bisnorcholenaldehyde from mother liquor of phytosterol fermentation using macroporous resin column chromatography followed by crystallization.” Journal of Chromatography B 1079 (2018): Pages 9-14.

BISNORCHOLENALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

21-hydroxy-20-methylpregn-4-en-3-one

BISNORCHOLENALDEHYDE Suppliers

Global( 39)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6739 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6514 58 Inquiry
BIONNA MEDICINE CO.,LTD 01056380788-8515; +8618518759099 China 52 58 Inquiry
Shenzhen Excellent Biomedical Technology Co.,Ltd. +undefined18318671572 China 1092 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11922 58 Inquiry
Guangzhou CATO Research Chemicals Inc. +86-020-81960175-617 +8615602392859 China 6428 58 Inquiry
Moxin Chemicals +8617320513646 China 9902 58 Inquiry
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. +8618950047208 China 43416 58 Inquiry
Aikon International Limited 025-58859352 18651614124 China 9199 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
SynZeal Research Pvt Ltd 58
BIONNA MEDICINE CO.,LTD 58
Shenzhen Excellent Biomedical Technology Co.,Ltd. 58
China National Standard Pharmaceutical Corporation Limited 58
Guangzhou CATO Research Chemicals Inc. 58
Moxin Chemicals 58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. 58
Aikon International Limited 58

BISNORCHOLENALDEHYDE Spectrum

BISNORCHOLENALDEHYDE(3986-89-8)MSBISNORCHOLENALDEHYDE(3986-89-8)1HNMRBISNORCHOLENALDEHYDE(3986-89-8)13CNMR

3986-89-8(BISNORCHOLENALDEHYDE)Related Search:

20α-Acetoxy-4-pregnen-3-one (17α)-Pregn-4-ene-3,20-dione 4-PREGNEN-20-ALPHA-OL-3-ONE 4,9(11)-PREGNADIEN-3,20-DIONE 4-PREGNEN-20-BETA-OL-3-ONE
1,4-PREGNADIEN-3,20-DIONE Progesterone EP Impurity G Progesterone EP Impurity F Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro 21ξ-morpholino-23,24-dinor-chola-4,20-dien-3-one
Androstenone hydrazone 17-Iodoandrosta-5,16-dien-3beta-ol tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate CarbaMic acid, [(2R)-2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]-, 1,1-diMethylethyl ester 2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)-
N-(1-Cyclohexen-1-yl)morpholine Abiraterone Pregna-4,6-diene-3,20-dione
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KETOBISNORALDEHYDE 3-KETO-4-PREGNENE-20-BETA-CARBOXALDEHYDE 4-PREGNEN-20BETA-CARBOXALDEHYDE-3-ONE 4-PREGNEN-3-ONE-20-BETA-CARBOXALDEHYDE Progesterone EP Impurity I Progesterone Impurity 7 Progesterone EP Impurity I (S-isomer) (20S)-3-oxopregn-4-ene-20-carboxaldehyde BNKY018-PG01 Bisnorcholeldehyde Pregn-4-ene-20-carboxaldehyde, 3-oxo-, (20S)- (S)-2-((8S,9S,10R,13S,14S,17R)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propanal 3-Oxo-pregn-4-ene-20α- carboxaldehyde Progesterone Impurity 24 (20S)-20-Formylpregn-4-en-3-one (S)-2-((8S,9S,10R,13S,14S,17R)-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propanal (Progesterone Impurity) Bisnorcholenaldehyde Progesterone EP Impurity I-02 Progesterone Impurity(S-Isomer) Didroprogesterone impurity 2 (2S)-2-[(8S,9S,10R,13S,14S,17R)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]propanal (2S)-2-[(8S,9S,10R,13R,14S,17R)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]propanal 3986-89-8