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3-(2-Pyrrolidinyl)pyridine

CAS No.: 5746-86-1

Chemical Name:: 3-(2-Pyrrolidinyl)pyridine

Synonyms: DL-NORNICOTINE;(R,S)-NORNICOTINE;Nornicotine;(±)-Nornicotine;NORNICOTINE, DL-;Nicotine USP RC F;(+/-)-nornicotine;DL-Nornicotine,96%;beta-dl-nornicotine;(+ -)-NORNICOTINE 98+%

CBNumber:: CB4385206

Molecular Formula:: C9H12N2

Molecular Weight:: 148.21

MOL File:: 5746-86-1.mol

Modify Date:: 2025/10/29 15:43:00

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3-(2-Pyrrolidinyl)pyridine Properties

Melting point	235-236 °C(Solv: ethanol (64-17-5))
Boiling point	107-108°C 2mm
Density	1,074 g/cm³
refractive index	1.54
Flash point	101°C
storage temp.	2-8°C
solubility	H₂O: 50 mg/mL
form	liquid
pka	9.09±0.10(Predicted)
color	yellow
Specific Gravity	1.074
Water Solubility	Soluble in acetone, chloroform and water (50mg/ml).
Merck	14,6712
BRN	81968
Stability	Hygroscopic, Light Sensitive, Moisture Sensitive
CAS DataBase Reference	5746-86-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312+H332-H315-H319-H335

Precautionary statements

P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338

Hazard Codes

Xn,Xi,T,F

Risk Statements

20/21/22-36/37/38-39/23/24/25-23/24/25-11

Safety Statements

26-36/37-45-16-7

RIDADR

2810

WGK Germany

RTECS

QS6350000

3-10

HazardClass

6.1

PackingGroup

III

HS Code

29399990

Toxicity

LDLo ipr-rat: 6 mg/kg AJEBAK 25,83,47

NFPA 704

	1
2		1

3-(2-Pyrrolidinyl)pyridine price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	N3018	(±)-Nornicotine ≥98% (TLC), liquid	5746-86-1	25MG	₹23111.38	2022-06-14	Buy
Sigma-Aldrich(India)	PHR3063	Nicotine Related Compound F pharmaceutical secondary standard, certified reference material	5746-86-1	50MG	₹41308.2	2022-06-14	Buy
Sigma-Aldrich(India)	N3018	(±)-Nornicotine ≥98% (TLC), liquid	5746-86-1	50MG	₹39900.95	2022-06-14	Buy
Sigma-Aldrich(India)	N-071	(±)-Nornicotine solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?	5746-86-1	1ML	₹9788.8	2022-06-14	Buy

Product number	Packaging	Price	Buy
N3018	25MG	₹23111.38	Buy
PHR3063	50MG	₹41308.2	Buy
N3018	50MG	₹39900.95	Buy
N-071	1ML	₹9788.8	Buy

3-(2-Pyrrolidinyl)pyridine Chemical Properties,Uses,Production

Description

(±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist. The α6 and α7 subunit-containing neuronal nAChRs are particularly responsive to nornicotine with EC₅₀ values of approximately 4 and 17 μM, respectively, when expressed in Xenopus oocytes. Nornicotine promotes cell migration and destabilizes cell-cell junctions in an endothelial cell line. It is generally thought to be free from abuse potential, but it has been self-administered by rats. It can be detected in urine.

Chemical Properties

Colourless Oil

Uses

3-(2-Pyrrolidinyl)pyridine is a tobacco alkaloid and the major Nicotine (N412420) metabolite in brain. Nornicotine appears to activate different nAChR subtypes, has a better pharmacokinetic profile, and produces less toxicity than Nicotine. Nornicotine shows a significant analgesic activity. Nicotine USP Related Compound F (3-(pyrrolidine-2-yl)pyridine).

Safety Profile

Poison by intraperitoneal route.When heated to decomposition it emits very toxic fumesof NOx and HCl. See also NORNICOTINE

3-(2-Pyrrolidinyl)pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

LY-2795050 NORNICOTINE, DL-(RG) (+/-)-NICOTINE

3-(2-Pyrrolidinyl)pyridine Suppliers

Global( 222)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6257	58	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6700	30	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6100	58	Inquiry
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	China	29735	60	Inquiry
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	China	13595	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49975	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29798	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	China	34563	58	Inquiry
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	China	52846	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471	China	10473	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
CHEMSWORTH	30
A.J Chemicals	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Zhejiang J&C Biological Technology Co.,Limited	58

3-(2-Pyrrolidinyl)pyridine Spectrum

3-(2-Pyrrolidinyl)pyridine(5746-86-1)¹HNMR

5746-86-1(3-(2-Pyrrolidinyl)pyridine)Related Search:

Pyridine Polyvinylpyrrolidone Pyrrolidine Povidone iodine N-Methyl-2-pyrrolidone

N-Vinyl-2-pyrrolidone 3-(Pyrrolidin-2-yl)pyridine hydrochloride 3-(pyrrolidin-2-yl)pyridine dihydrochloride (+)-3-[(2R)-1-Methyl-2-pyrrolidinyl]pyridine,3-[(2R)-1-Methyl-2-pyrrolidinyl]pyridine Nicotine

(+/-)-COTININE-D3 (-)-COTININE (+/-)-NICOTINE-METHYL-D3 (+/-)-COTININE-D3 NICOTINE DITARTRATE DIHYDRATE

(S)-3-(1-METHYL-2-PYRROLIDINYL)PYRIDINE, DI-D-TARTRATE,(S)-3-(1-METHYL-2-PYRROLIDINYL)PYRIDINE TARTRATE SALT 4-(2-PYRROLIDINYL)PYRIDINE METHYL-2-PYRROLIDONE

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NORNICOTINE, DL- (+-)-1’-demethylnicotine beta-dl-nornicotine 3-PYRROLIDIN-2-YLPYRIDINE 2-[3-PYRIDYL]PYRROLIDINE 2-[3-PYRIDYL]PYRROLIDONE (+/-)-3-(2-PYRROLIDINYL)PYRIDINE 3-(2-PYRROLIDINYL)PYRIDINE DL-2-(3-Pyridyl)pyrrolidine (+ -)-NORNICOTINE 98+% DL-Nornicotine,96% 2-(3-Pyridyl)pyrrolidine, 3-(2-Pyrrolidinyl)pyridine Nicotine, 1'-demethyl-, (+-)- Pyridine, 3-(2-pyrrolidinyl)-, (+-)- (9ci) (±)-Nornicotine,2-(3-Pyridyl)pyrrolidine, 3-(2-Pyrrolidinyl)pyridine DL-Nornicotine/3-(Pyrrolidin-2-yl)pyridine 2-(3-Pyridinyl)pyrrolidine 2-(Pyridin-3-yl)pyrrolidine (RS)-Nornicotine (1.0 Mg/ML in Methanol) 3-(2-Pyrrolidyl)pyridine (±)-Nornicotine solution Pyridine, 3-(2-pyrrolidinyl)- Nicotine Related Compound F Nicotine USP RC F Nicotine USP Related Compound F (rac-Nicotine EP Impurity F) Nicotine Related Compound F (20 mg) (2S)-2-(3-Pyridinyl)pyrrolidinium (+/-)-nornicotine (R,S)-NORNICOTINE DL-NORNICOTINE (+/-)-Nornicotine, 3-(2-Pyrrolininyl)pyridine 3-[(2S)-pyrrolidin-2-yl]pyridine (nornicotine) Nicotine EP Impurity F as Racemate rac-Nicotine EP Impurity F Sertindole Impurity 20 3-[(2RS)-Pyrrolidin-2-yl]pyridine ((RS)-Nornicotine) (±)-Nornicotine solution (±)-Nornicotine (+-)-1’-demethylnicotine (+ -)-NORNICOTINE 98+% Nornicotine 5746-86-1 AMINE BioChemical Cell Biology Cell Signaling and Neuroscience Ion Channels Ligand-Gated Ion Channels Nicotinic Acetylcholine Receptor Modulators Metabolites & Impurities Aromatics Chiral Reagents Heterocycles Mutagenesis Research Chemicals pharmacetical Nicotine Derivatives Benzenes Heterocycle-Pyridine series