Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate

Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate Structure
CAS No.
289042-11-1
Chemical Name:
Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate
Synonyms
Z-6;ZD-1 ;AKOS 91016;Methyl 4-(4-fluoroph;Rosuvastatin Impurity 25;Rosuvastatin Impurity 72;Rosuvastatin Impurity Z-6;rosuvastatin intermediates Z-6;Rosuvastatin intermediate R-1-1;Rosuvastatin Intermediate Impurity 1
CBNumber:
CB8177348
Molecular Formula:
C17H20FN3O4S
Molecular Weight:
381.42
MOL File:
289042-11-1.mol
MSDS File:
SDS
Modify Date:
2024/4/26 21:57:37

Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate Properties

Melting point 127-129°C
Boiling point 552.0±60.0 °C(Predicted)
Density 1.304±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form Solid
pka -1.85±0.10(Predicted)
color White
CAS DataBase Reference 289042-11-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H361-H412
Precautionary statements  P201-P202-P281-P308+P313-P405-P501-P273-P501

Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate Chemical Properties,Uses,Production

Uses

An intermediate of Rosuvastatin (R700500).

Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[(METHANESULFONYL)METHYLAMINO]PYRIMIDINE-5-CARBOXYLIC ACID METHYL ESTER METHYL 4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[(N-METHYL-N-METHANESULFONYL)-AMINO]-PYRIMIDINE-5-CARBOXYLATE methyl 4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyrimidine-5-carboxylate R1-METHYL-4-(FLUOROMETHYL)-6-ISOPROPYL-2-(N-METHYLSULFONYLAMINO)PYRIMIDINO-5-CARBOXYLATE Rosuvastatin intermediate R-1-1 ZD-1 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulfonylamino)Pyrimidine-5-Carboxylate ( Carboxylate) 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulfonyl amino)Pyrimidine-5-Carboxylate 4-(4-fluoropheny)-6-isopropyl-2-(N- methyl-N-methylsulfonylamino)pyrimidine-5-carboxylate Methyl 4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-N-Methylsulfonyl)aMino]pyriMidine-5-carboxylate(Z6) Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylat 5-PyriMidinecarboxylic acid, 4-(4-fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(Methylsulfonyl)aMino]-, Methyl ester Tertiary-butyl-(+)- (4-fluorophenyl)-6-isopropyl-2-(n-Methyl,n-Methyl sulphonyl aMino) pyriMidine-5-yl -(3r-5s)-dioxane-(e)-6 heptane Also known as 4-(4-fluorophenyl)-6-isopropyl-2-(n-Methyl-n-MethylsulfonylaMino)pyriMidine-5-carboxylate methyl 4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidine-5-carboxylate Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonamido)pyrimidine-5-carboxylate rosuvastatin intermediates Z-6 Z-6: 4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[(N-METHYL Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxy 4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidine-5-carboxylate Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino] pyriminl-5-yl-carboxylate Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino] 4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl)methylamino]pyrimidine-5-carboxylic acid methyl Methyl 4-(4-fluoroph Z-6 AKOS 91016 Methyl-(4-fluorophenyl)6-isopropyl-2-(N-Methyl-N-Methylsulfonyl) aMino pyriMidine-5-carboxylate (ZD-1) Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[(N-Methyl-N-Methylsulfonyl)aMino]pyriMidine-5-carboxylate 4-(4-Fluorophenyl)-6-isopropyl-2- [(N-methyl-N-methylsulfony)amino]pyrimidine-5-carboxylate Tertiary-butyl-(+)-[(4-fluorophenyl)-6-lsopropyl -2-(N-methyl,N-methyl sulphonyl amio)pyrimdine-5 -yl]-(3R-5S)dioxane-(E)-6 heptane METHYL4-(-4FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYLSULFONYLAMINO)PYRIMIDINE-5-CARBOXYLATE 4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine-5-methyleneoxide 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]Pyrimidine-5-carboxalate Rosuvastatin Impurity 25 Rosuvastatin Impurity 72 Methyl4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methanesulfonylamino) Pyrimidin-5-Carboxylate Rosuvastatin Impurity Z-6 METHYL 4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[(N-METHYL-N-METHYLSULFONYL)AMINO]PYRIMIDINE-5-CARBOXYL Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n methylsulfonyl)amino]pyriminl-5-yl-carboxylate(Z6) Methyl 4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-methyl-N-methyls... TIANFU CHEM-Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate Methyl 4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(methanesulfonamido)pyrimidine-5-carboxylate Rosuvastatin Intermediate Impurity 1 Methyl 4- (4-fluorophenyl)-6-isopropyl-2- [methyl (methylsulfonyl) amino] pyrimidine-5 carboxylate 4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl)methylamino]pyrimidine-5-carboxylic acid methyl ester 289042-11-1 C17H20FN3O4S Rosuvastatin Calcium and its intermediates Amines Aromatics Bases & Related Reagents Heterocycles Nucleotides Sulfur & Selenium Compounds Rosuvastatin intermediates INTERMEDIATESOFROSUVASTATINCALCIUM