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Vardenafil hydrochloride trihydrate

330808-88-3

CAS番号.: 330808-88-3

化学名:

别名:

英語名:: Vardenafil hydrochloride trihydrate

英語别名:: VARDENAFIL HYDROCHLORIDE TRIHYDRATE;Vardenafil hydrochloride CRS;Vardenafil for system suitability;Vardenafil Hydrochloride (1711010);vardenafil hydrochloride trihyrate;Verdenafil Hydrochloride Trihydrate;2-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride hydrate;2-(2-Ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride trihydrate;2-[2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one,hydrochloride, hydrate (1:1:3);IMidazo[5,1-f][1,2,4]triazin-4(1H)-one,2-[2-ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-5-Methyl-7-propyl-,hydrochloride, hydrate (1:1:3)

CBNumber:: CB01230855

化学式:: C23H35ClN6O5S

分子量:: 543.08

MOL File:: 330808-88-3.mol

物理性質

安全性情報

価格10

用途語

生産企業 95

スペクトル

Vardenafil hydrochloride trihydrate 物理性質

貯蔵温度 :: under inert gas (nitrogen or Argon) at 2-8°C

溶解性:: ≥13.3 mg/mL in DMSO; ≥3.42 mg/mL in EtOH with gentle warming and ultrasonic; ≥95 mg/mL in H2O

安全性情報

リスクと安全性に関する声明
危険有害性情報のコード(GHS)

RIDADR	UN 2811 6.1 / PGIII
HSコード	2933595960

絵表示（GHS）

注意喚起語

危険

危険有害性情報

コード	危険有害性情報	危険有害性クラス	区分	注意喚起語	シンボル	P コード
H301	飲み込むと有毒	急性毒性、経口	3	危険		P264, P270, P301+P310, P321, P330,P405, P501
H373	長期にわたる、または反復暴露により臓器の障害のおそれ	特定標的臓器有害性、単回暴露	2	警告		P260, P314, P501

注意書き

P260	粉じん/煙/ガス/ミスト/蒸気/スプレーを吸入しないこと。
P264	取扱い後は皮膚をよく洗うこと。
P264	取扱い後は手や顔をよく洗うこと。
P270	この製品を使用する時に、飲食または喫煙をしないこと。
P301+P310	飲み込んだ場合：直ちに医師に連絡すること。
P314	気分が悪い時は、医師の診断/手当てを受けること。
P405	施錠して保管すること。

Vardenafil hydrochloride trihydrate 価格もっと(10)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01COBQC-2658	Vardenafil hydrochloride trihydrate	330808-88-3	1g	￥20000	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01COBQC-2658	Vardenafil hydrochloride trihydrate	330808-88-3	5g	￥60000	2024-03-01	購入
Sigma-Aldrich Japan	Y0001647	European Pharmacopoeia (EP) Reference Standard Vardenafil hydrochloride trihydrate European Pharmacopoeia (EP) Reference Standard	330808-88-3	y0001647	￥19400	2024-03-01	購入
Sigma-Aldrich Japan	PHR2720	certified reference material, pharmaceutical secondary standard Vardenafil Hydrochloride certified reference material, pharmaceutical secondary standard	330808-88-3	500MG	￥40400	2024-03-01	購入
Sigma-Aldrich Japan	1711010	United States Pharmacopeia (USP) Reference Standard Vardenafil hydrochloride United States Pharmacopeia (USP) Reference Standard	330808-88-3	200mg	￥54400	2024-03-01	購入

Vardenafil hydrochloride trihydrate 化学特性,用途語,生産方法

説明

Vardenafil is a potent inhibitor of phosphodiesterase 5 (PDE5; IC₅₀s = 0.2-1.2 nM) and PDE6 (IC₅₀ = 2 nM). It is selective for PDE5 and PDE6 over PDE1 and PDE11 (IC₅₀s = 230 and 130 nM, respectively). Vardenafil (4 mg/kg per day for three weeks) improves erectile function in a rat model of acute arteriogenic erectile dysfunction by increasing intracavernous pressure and mean arterial pressure, and this effect persists for at least two weeks following the end of treatment. Chronic vardenafil administration at a dose of 2 mg/kg for five weeks in subordinate mice reduces the latency to mount and increases the frequency of mounting behavior. Formulations containing vardenafil have been used in the treatment of erectile dysfunction.

使用

Vardenafil hydrochloride trihydrate is a potent inhibitor of PDE5 (IC50 = 0.2-1.2 nM) that less effectively blocks the activities of PDE6, PDE1, and PDE11 (IC50s = 2, 230, and 130 nM, respectively). PDE5 inhibitors, including vardenafil, have applications in several conditions, including erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction.[Cayman Chemical]

Vardenafil hydrochloride trihydrate 上流と下流の製品情報

原材料

準備製品

Vardenafil hydrochloride trihydrate 生産企業

Global( 95)Suppliers

名前	電話番号	電子メール	国籍	製品カタログ	優位度
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Shanghai Longyu Biotechnology Co., Ltd.	+8615821988213	info@longyupharma.com	China	2531	58
Baoji Guokang Bio-Technology Co., Ltd.	0917-3909592 13892490616	gksales1@gk-bio.com	China	9339	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Nanjing Doge Biomedical Technology Co., Ltd	+86-25-58227606 +86-15305155328	sales@dogechemical.com	China	4128	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58

スペクトルデータ(¹HNMR)

Vardenafil hydrochloride trihydrate(330808-88-3)¹HNMR

330808-88-3()キーワード:

バルデナフィル塩酸塩 1-[2-[ビス(4-フルオロフェニル)メトキシ]エチル]-4-(3-フェニルプロピル)ピペラジン Nインテダニブバルスポダールバキノール-1 バンデタニブ

330808-88-3
IMidazo[5,1-f][1,2,4]triazin-4(1H)-one,2-[2-ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-5-Methyl-7-propyl-,hydrochloride, hydrate (1:1:3)
Vardenafil for system suitability
Verdenafil Hydrochloride Trihydrate
Vardenafil hydrochloride CRS
2-(2-Ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride trihydrate
vardenafil hydrochloride trihyrate
Vardenafil Hydrochloride TrihydrateQ: What is Vardenafil Hydrochloride Trihydrate Q: What is the CAS Number of Vardenafil Hydrochloride Trihydrate Q: What is the storage condition of Vardenafil Hydrochloride Trihydrate
Vardenafil Hydrochloride (1711010)
2-[2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one,hydrochloride, hydrate (1:1:3)
VARDENAFIL HYDROCHLORIDE TRIHYDRATE
2-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride hydrate