グルカゴン様ペプチドI, ヒト

グルカゴン様ペプチドI, ヒト 化学構造式
87805-34-3
CAS番号.
87805-34-3
化学名:
グルカゴン様ペプチドI, ヒト
别名:
グルカゴン様ペプチドI, ヒト
英語名:
GLP-1
英語别名:
GLP-1;GLP-1 (HUMAN);GLP-1 USP/EP/BP;Rat GLP-I(1-37);GLP-1, 5mg/vial;GATA-like protein 1;GLP-1 (1-37) (human);PREPROGLUCAGON 72-108;GLUCAGON-LIKE PEPTIDE I;Glucagon-likepeptide1(1-37)
CBNumber:
CB0193173
化学式:
C186H275N51O59
分子量:
4169.48
MOL File:
Mol file

グルカゴン様ペプチドI, ヒト 物理性質

貯蔵温度 :
−20°C
外見 :
Solid
水溶解度 :
Soluble to 5 mg/ml in water
InChIKey:
UKVFVQPAANCXIL-FJVFSOETSA-N
CAS データベース:
87805-34-3
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
WGK Germany  3
HSコード  3504009000
絵表示(GHS) GHS hazard pictograms
注意喚起語
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H315 皮膚刺激 皮膚腐食性/刺激性 2 警告 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 強い眼刺激 眼に対する重篤な損傷性/眼刺激 性 2A 警告 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 呼吸器への刺激のおそれ 特定標的臓器毒性、単回暴露; 気道刺激性 3 警告 GHS hazard pictograms
注意書き
P261 粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。
P271 屋外または換気の良い場所でのみ使用すること。
P280 保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

グルカゴン様ペプチドI, ヒト 価格 もっと(7)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01BCS4037542
GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat), H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-
87805-34-3 0.5mg ¥95000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01TOC1851
Glucagon-like peptide 1 (1-37) (human, rat)
87805-34-3 1mg ¥158000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01BCS4037542
GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat), H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-
87805-34-3 1mg ¥152000 2024-03-01 購入
Sigma-Aldrich Japan G3265 グルカゴン様ペプチドI, ヒト ≥97% (HPLC)
Glucagon-Like Peptide I human ≥97% (HPLC)
87805-34-3 0.1mg ¥37900 2024-03-01 購入
Sigma-Aldrich Japan G3265 グルカゴン様ペプチドI, ヒト ≥97% (HPLC)
Glucagon-Like Peptide I human ≥97% (HPLC)
87805-34-3 0.5mg ¥75300 2024-03-01 購入

グルカゴン様ペプチドI, ヒト 化学特性,用途語,生産方法

来歴

GLP-1 was first identified in the early 1980s, following the cloning of the proglucagon gene. The biological activity of GLP-1 was investigated initially by using the N-terminal extended forms of GLP-1(1–37 and 1–36 amide). However, these forms were devoid of biological activity. In the late 1980s, bioactive GLP-1 peptides were purified from gut extracts and were identified to be GLP1(7–37) and GLP-1(7–36)-amide. In the current literature, the unqualified designation of GLP-1 corresponds to the truncated peptides.

使用

Glucagon-Like Peptide I (GLP1) has been used as an antigen in excess amounts for the incubation of primary antibodies, post-immunocytochemistry with positive results of paraffin-embedded pancreatic tissues of Rana temporaria.

一般的な説明

Glucagon-Like Peptide I (GLP1) is an incretin hormone, which functions as ligand for GLP1 receptors (GLP1R). These receptors are expressed in renal and cardiovascular system, such as smooth muscle and endothelial cells.

Biochem/physiol Actions

Glucagon-Like Peptide I (GLP1) controls the metabolism of glucose, by inducing the secretion of insulin and suppressing that of glucagon. Studies in Indonesian population show that reduced levels of this protein are linked with increased susceptibility to type 2 diabetes mellitus. Plasma levels of this hormone also show significant association with systolic and diastolic blood pressure levels.

グルカゴン様ペプチドI, ヒト 上流と下流の製品情報

原材料

準備製品


グルカゴン様ペプチドI, ヒト 生産企業

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87805-34-3(グルカゴン様ペプチドI, ヒト)キーワード:


  • 87805-34-3
  • HIS-ASP-GLU-PHE-GLU-ARG-HIS-ALA-GLU-GLY- THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARGY-GLY
  • GLUCAGON-LIKE PEPTIDE I HUMAN
  • GLUCAGON-LIKE PEPTIDE-1, HUMAN
  • GLUCAGON-LIKE PEPTIDE I
  • GLUCAGON-LIKE PEPTIDE 1 (1-37) (HUMAN)
  • GLUCAGON-LIKE PEPTIDE 1 (1-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • GLUCAGON-LIKE PEPTIDE 1 (1-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT) TRIFLUOROACETATE SALT
  • GLP-1
  • GLP-1 (1-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • GLP-1 (1-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT) TRIFLUOROACETATE SALT
  • GLP-1 (HUMAN)
  • Glucagon-likepeptide1(1-37)
  • glucagon-like peptide I (1-37)
  • PREPROGLUCAGON 72-108
  • PREPROGLUCAGON (92-128) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT) TRIFLUOROACETATE SALT
  • PROGLUCAGON (72-108) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT) TRIFLUOROACETATE SALT
  • M.W. 4169.54 C186H275N51O59
  • HIS-ASP-GLU-PHE-GLU-ARG-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY
  • Glucagon-like peptide 1 (1-37) (human, rat)
  • GLP-1 (1-37) (huMan, bovine, guinea pig, Mouse, rat) Preproglucagon (92-128) (huMan, bovine, guinea pig, Mouse, rat), Proglucagon (72-108) (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (1-37) (huMan, bovine, guinea pig, Mouse, rat)
  • Preproglucagon (92-128) (huMan, bovine, guinea pig, Mouse, rat), Proglucagon (72-108) (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (1-37) (huMan, bovine, guinea pig, Mouse, rat)
  • GLP-1 (1-37) (human, bovine, gp, mouse, rat)
  • ANTI-GLP1 (CENTER) antibody produced in rabbit
  • GATA-like protein 1
  • H-HIS-ASP-GLU-PHE-GLU-ARG-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH
  • GLP-1 USP/EP/BP
  • Rat GLP-I(1-37)
  • GLP-1, 5mg/vial
  • GLP-1 (1-37) (human)
  • グルカゴン様ペプチドI, ヒト
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