モノクローナル抗MDMX抗体 マウス宿主抗体

モノクローナル抗MDMX抗体 マウス宿主抗体 価格 もっと(12)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
Sigma-Aldrich Japan	SAB4501852	affinity isolated antibody Anti-MDM4 antibody produced in rabbit affinity isolated antibody		100μG	￥97700	2024-03-01	購入
Sigma-Aldrich Japan	SAB4501849	affinity isolated antibody Anti-MDM2 antibody produced in rabbit affinity isolated antibody		100μG	￥97700	2024-03-01	購入
Sigma-Aldrich Japan	SAB4300601	affinity isolated antibody Anti-MDM2 (Ab-166) antibody produced in rabbit affinity isolated antibody		100μG	￥64100	2024-03-01	購入
Sigma-Aldrich Japan	M0445	モノクロナール抗MDMX マウス宿主抗体 clone MDMX-82, purified from hybridoma cell culture Monoclonal Anti-MDMX antibody produced in mouse clone MDMX-82, purified from hybridoma cell culture		100μL	￥104000	2024-03-01	購入
Sigma-Aldrich Japan	SAB4300284	affinity isolated antibody Anti-phospho-MDM2 (pSer166) antibody produced in rabbit affinity isolated antibody		100μG	￥105000	2024-03-01	購入

モノクローナル抗MDMX抗体 マウス宿主抗体 化学特性,用途語,生産方法

使用

Monoclonal Anti-MDMX antibody is suitable for use in immunocytochemistry, immunoprecipitation, immunoblot (approx. 80 kDa), microarray, and ELISA. The product may also be used for western blot and for assessing ectopic expression of MDMX (using a conc. of 1-2 μg/mL in total cell extract of HEK 293T cells transfected with human MDMX).

一般的な説明

Monoclonal Anti-MDMDX (mouse IgG1 isotype) is derived from the hybridoma MDMX-82 produced by the fusion of mouse myeloma cells (NS1 cells) and splenocytes from BALB/c mice. MDMX belongs to the MDM family. The MDMX/ mouse double minute 4 (MDM4) gene encode a 490 amino acid protein. MDMX comprises a putative nuclear localization signal, a really interesting new gene (RING) finger domain in the C terminal and a p53-binding domain in the N terminal. MDMX has significant structural similarity to MDM2 E3 ubiquitin ligase.

Biochem/physiol Actions

MDMX is a structural homolog of MDM2 and inhibits the tumor suppressor, p53. MDMX also prevents MDM2-mediated degradation of p53, and subsequently regulates cellular levels of p53. MDMX also modulates cell growth and survival. Thus, MDMX can be useful as a therapeutic target in cancers, especially in tumors where native p53 functions can be restored . Monoclonal Anti-MDMX antibody is specific for human MDMX.

モノクローナル抗MDMX抗体 マウス宿主抗体 上流と下流の製品情報

原材料

準備製品

モノクローナル抗MDMX抗体 マウス宿主抗体 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shanghai guandao biology engineering co., ltd	18818239863 18818239863	3171921642@qq.com	China	8884	58
Shanghai Huzhen Industrial Co., LTD	021-60345367 13916550749	sales@shzbio.com	China	9965	58

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• ANTI-UBIQUITIN PROTEIN LIGASE
• ANTI-UBIQUITIN PROTEIN LIGASE (AB-1), HUMAN
• p53-binding protein Mdm2
• Ubiquitin-protein ligase E3 Mdm2
• double minute 4 protein
• Mdm2-like p53-binding protein
• MDMX
• p53-binding protein Mdm4
• Anti-Double minute 4 protein
• Anti-Mdm2-like p53-binding protein
• Anti-MDM4 antibody produced in rabbit
• Anti-p53-binding protein Mdm4
• Anti-Protein Mdm4
• Anti-Protein Mdmx
• Anti-HGNC:6973
• Anti-MDM2 (Isoform) antibody produced in goat
• Anti-Transformed 3T3 cell double minute 2
• Anti-MDM2 (Ab-166) antibody produced in rabbit
• Anti-hdm2 antibody produced in rabbit
• Anti-HDMX antibody produced in rabbit
• Anti-Mdm2 p53 binding protein homolog (mouse) antibody produced in rabbit
• Anti-MGC71221 antibody produced in rabbit
• Anti-phospho-MDM2 (pSer166) antibody produced in rabbit
• Anti-Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse)
• HDMX
• MDM2, untagged human
• MGC5370
• MGC71221
• Anti-MDM2 antibody produced in chicken
• Anti-Mouse double minute 2 homolog isoform MDM2
• モノクローナル抗MDMX抗体 マウス宿主抗体