Sofosbuvir IMpurity B

 化学構造式
1496552-51-2
CAS番号.
1496552-51-2
化学名:
别名:
英語名:
Sofosbuvir IMpurity B
英語别名:
Sofosbuvir impurity K;Sofosbuvir IMpurity B;Sofosbuvir Chloro Analog;Sofosbuvir Chloro Analogue;sofosbuvir impurity Y008005-K;L-Alanine, N-[[P(S),2'R]-2'-chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester;((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-chloro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate;(2S)-isopropyl 2-(((((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate;(S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
CBNumber:
CB02716563
化学式:
C22H29ClN3O9P
分子量:
545.91
MOL File:
1496552-51-2.mol

Sofosbuvir IMpurity B 物理性質

比重(密度) :
1.43±0.1 g/cm3(Predicted)
貯蔵温度 :
Store at -20°C
溶解性:
Soluble in DMSO
酸解離定数(Pka):
9.39±0.10(Predicted)

安全性情報

Sofosbuvir IMpurity B 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

Sofosbuvir IMpurity B 化学特性,用途語,生産方法

使用

Chloro Sofosbuvir is an impurity of Sofosbuvir (P839640); a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled Sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

Sofosbuvir IMpurity B 上流と下流の製品情報

原材料

準備製品


Sofosbuvir IMpurity B 生産企業

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1496552-51-2()キーワード:


  • 1496552-51-2
  • Sofosbuvir IMpurity B
  • (S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
  • Sofosbuvir impurity K
  • Sofosbuvir Chloro Analogue
  • L-Alanine, N-[[P(S),2'R]-2'-chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester
  • Sofosbuvir Chloro Analog
  • sofosbuvir impurity Y008005-K
  • (2S)-isopropyl 2-(((((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
  • ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-chloro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
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