Diminutol

 化学構造式
361431-33-6
CAS番号.
361431-33-6
化学名:
别名:
英語名:
Diminutol
英語别名:
NG72;Diminutol;1-Butanol, 2-[[6-[(3-aminophenyl)thio]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-, (2R)-
CBNumber:
CB02756303
化学式:
C19H26N6OS
分子量:
386.51
MOL File:
361431-33-6.mol

Diminutol 物理性質

貯蔵温度 :
Store at -20°C
溶解性:
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
外見 :
A crystalline solid

安全性情報

Diminutol 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

Diminutol 化学特性,用途語,生産方法

説明

Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization.

使用

Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization.[Cayman Chemical]

Diminutol 上流と下流の製品情報

原材料

準備製品


Diminutol 生産企業

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  • 361431-33-6
  • Diminutol
  • 1-Butanol, 2-[[6-[(3-aminophenyl)thio]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-, (2R)-
  • NG72
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