6-ヒドロキシドーパミン·塩酸塩
6-ヒドロキシドーパミン·塩酸塩 物理性質
- 融点 :
- 232-233 °C (dec.)(lit.)
- 貯蔵温度 :
- room temp
- 溶解性:
- H2O: >50 mg/mL、透明、黄色から茶色
- 外見 :
- 粉
- 色:
- オフホワイトからブラウン
- BRN :
- 4274007
- InChI:
- InChI=1S/C8H11NO3.ClH/c9-2-1-5-3-7(11)8(12)4-6(5)10;/h3-4,10-12H,1-2,9H2;1H
- InChIKey:
- QLMRJHFAGVFUAC-UHFFFAOYSA-N
- SMILES:
- C1(CCN)=CC(=C(O)C=C1O)O.Cl
- EPAの化学物質情報:
- 6-Hydroxydopamine hydrochloride (28094-15-7)
6-ヒドロキシドーパミン·塩酸塩 価格
もっと(3)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
Sigma-Aldrich Japan
|
H4381 |
6-ヒドロキシドーパミン 塩酸塩 ≥97% (titration), powder
6-Hydroxydopamine hydrochloride ≥97% (titration), powder |
28094-15-7 |
100mg |
￥34500 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
H4381 |
6-ヒドロキシドーパミン 塩酸塩 ≥97% (titration), powder
6-Hydroxydopamine hydrochloride ≥97% (titration), powder |
28094-15-7 |
500mg |
￥135000 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
H4381 |
6-ヒドロキシドーパミン 塩酸塩 ≥97% (titration), powder
6-Hydroxydopamine hydrochloride ≥97% (titration), powder |
28094-15-7 |
1g |
￥133000 |
2024-03-01 |
購入 |
6-ヒドロキシドーパミン·塩酸塩 化学特性,用途語,生産方法
使用
6-hydroxydopamine hydrochloride has been used:
- to induce Parkinson′s disease (PD) in rats
- to analyse cytotoxic effect of 6-OHDA on PC12 cell line
- to induce noradrenergic (NA) neuron deletion from the locus-coeruleus
一般的な説明
Beige solid.
空気と水の反応
Hygroscopic. Water soluble.
反応プロフィール
A weak acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.
健康ハザード
ACUTE/CHRONIC HAZARDS: When heated to decomposition 6-HYDROXYDOPAMINE HYDROCHLORIDE emits very toxic fumes.
火災危険
Flash point data for 6-HYDROXYDOPAMINE HYDROCHLORIDE are not available. 6-HYDROXYDOPAMINE HYDROCHLORIDE is probably combustible.
生物活性
Selective catecholaminergic neurotoxin. Depletes brain catecholamine levels via uptake and accumulation by a transport mechanism specific to these neurons. Causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats, producing an animal model of Parkinson's disease.
6-ヒドロキシドーパミン·塩酸塩 上流と下流の製品情報
原材料
準備製品
6-ヒドロキシドーパミン·塩酸塩 生産企業
Global( 100)Suppliers
6-ヒドロキシドーパミン·塩酸塩 スペクトルデータ(1HNMR、FT-IR、IR、Raman)
28094-15-7(6-ヒドロキシドーパミン·塩酸塩)キーワード:
- 28094-15-7
- 4-(2-Aminoethyl)-1,2,3-benzenetriol hydrochloride
- 6-Hd HCl
- Nsc233898
- OxidopaMine Hydrochloride
- 2,4,5-TrihydroxyphenethylamineHCl
- 2,4,5-Trihydroxyphenethylaminehydochloride
- 2,4,5-TRIHYDROXYPHENETHYLAMINEYDOCHLORIDE
- 2,4,5-Trihydroxyphenethylamine hydrochloride, 2,5-Dihydroxytyramine hydrochloride, 2-(2,4,5-Trihydroxyphenyl)ethylamine hydrochloride, 6-OHDA
- 1,2,3-Benzenetriol, 4-(2-aminoethyl)-, hydrochloride
- 1,2,4-Benzenetriol, 5-(2-aminoethyl)-, hydrochloride
- 2,4,5-TRIHYDROXYPHENETHYLAMINE HYDROCHLORIDE
- 2,5-DIHYDROXYTYRAMINE HYDROCHLORIDE
- 2-(2,4,5-TRIHYDROXYPHENYL)ETHYLAMINE HYDROCHLORIDE
- TIMTEC-BB SBB003496
- 2,4-benzenetriol,5-(2-aminoethyl)-hydrochloride
- 5-(2-aminoethyl)-1,2,4-benzenetriolhydrochloride
- 6-hydroxydopaminechloride
- 5-(2-aminoethyl)-4-hydroxypyrocatechol hydrochloride
- TopaMine Hydrochloride
- 5-(2-aMinoethyl)benzene-1,2,4-triol hydrochloride
- OxydopaMine HCL
- 6-HYDROXYDOPAMINE HYDROCHLORIDE
- 6-Hydroxydopamine hy
- 6-OHDA hydrochloride
- 6-OHDA
- Neuro-2a cells,p-p38,Interleukin Related,p38 MAPK,PC12 cells,Apoptosis,Dopamine Receptor,Mitophagy,neurotoxicity,Autophagy,Oxidopamine hydrochloride,6-OHDA,Prostaglandin E synthase,Cyclooxygenase,Lesch-Nyhan syndrome,inhibit,Mitochondrial Autophagy,PGE2,attention-deficit hyperactivity disorder,Parkinson’s disease,SH-SY5Y cells,Oxidopamine,Caspase,PGE synthase,Inhibitor,COX,6-Hydroxydopamine
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- 6-ヒドロキシドーパミン 塩酸塩