イプリフラボン 化学特性,用途語,生産方法
外観
白色~うすい黄色, 結晶~粉末
溶解性
ジクロロメタン、N,N-ジメチルホルムアミドに易溶。アセトンに可溶。水、エーテルに不溶エタノール、メタノール及びアセトンに溶け、水にほとんど溶けない。
用途
骨粗鬆症における骨量減少の改善研究用。
用途
直接的な骨吸収抑制作用、エ ストロゲンのカルシトニン分泌促進作用を示 します。
用途
直接的な骨吸収抑制作用、エ
ストロゲンのカルシトニン分泌促進作用を示
します。
効能
骨粗鬆症治療薬
商品名
オステン (武田テバ薬品)
説明
Ipriflavone, a derivative of isoflavone, is a calcium metabolism regulator useful in the
treatment of primary and secondary osteoporosis, as well as disorders of osteogenesis. It
appears to be without significant side-effects.
化学的特性
white powder
使用
7-Isopropoxy-3-phenyl-4
H-1-benzopyran-4-one (Ipriflavone) has been used as a model drug in a study to functionalize the mesoporous bioactive glasses (MBG). Study suggested that since ipriflavone is a hydrophobic anti-osteoporotic drug, it easily attaches to the surface of MBG and results in long-term drug delivery.
定義
ChEBI: Ipriflavone is a member of the class of isoflavones that is isoflavone in which the hydrogen at position 7 is replaced by an isopropoxy group. A synthetic isoflavone, it was formerly used for the treatment of osteoporosis, although a randomised controlled study failed to show any benefit. It is still used to prevent osteoporosis in post-menopausal women. It has a role as a bone density conservation agent. It is a member of isoflavones and an aromatic ether.
利点
Ipriflavone is used clinically to treat osteoporosis. Bodybuilders also use ipriflavone, but enough experimental data supports this purpose. It has been shown to have anti-inflammatory and antioxidant activity. It helps to reduce bone loss, increase bone density, and reduce the risk of developing osteoporosis. It has also been found to help reduce neuroinflammation . In addition, it has been found to help reduce the risk of certain types of cancer, improve cognitive function and reduce the risk of depression.
一般的な説明
7-Isopropoxy-3-phenyl-4
H-1-benzopyran-4-one (Ipriflavone), a synthetic flavonoid, is reported to stimulate the activity of osteoblasts. It is reported to promote the deposition of calcium and the formation of mineralized nodules by newborn rat calvarial osteoblast-like (ROB) cells as well as the activity of alkaline phosphatase. Ipriflavone, an isoflavone derivative, is a new drug used to decrease bone loss in osteoporosis.
副作用
Ipriflavone should be taken under medical supervision only. It can produce side effects such as stomach pain, diarrhoea, dizziness, etc. It may have a sudden increase in the WBC count if administered for six months or more. When the treatment with Ipriflavone is on, it is suggested that the WBC count should be monitored.
イプリフラボン 上流と下流の製品情報
原材料
準備製品