葉酸メチルカルシウム塩

葉酸メチルカルシウム塩 化学構造式
151533-22-1
CAS番号.
151533-22-1
化学名:
葉酸メチルカルシウム塩
别名:
(6R,S)-5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, CA SALT;葉酸メチルカルシウム塩;レボメフォラートカルシウム;レボメホリナートカルシウム
英語名:
Levomefolate calcium
英語别名:
l-5-methylfolate;Calcium levomefolate;L-5-Methyltetrahydrofolate calcium;LMCA;Deplin;Bodyfolin;Nutrifolin;L-5-MTHF-Ca;L-5-Methyltetra;6S-5-methylfolate
CBNumber:
CB11420680
化学式:
C20H27CaN7O6
分子量:
501.56
MOL File:
151533-22-1.mol

葉酸メチルカルシウム塩 物理性質

融点 :
>300°C
貯蔵温度 :
Inert atmosphere,2-8°C
溶解性:
酸水溶液(加温)、水(微加温)
外見 :
個体
色:
オフホワイトからライトイエロー
臭い (Odor):
100.00%で。無臭
InChIKey:
CZDUXPNTZGHMRC-ZPZVDPIKNA-N
SMILES:
CN1[C@H](CNC2NC(N)=NC(=O)C1=2)CNC1C=CC(C(=O)N[C@H](C(=O)O)CCC(=O)O)=CC=1.[Ca] |&1:2,22,r|
CAS データベース:
151533-22-1
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
Sフレーズ  24/25
HSコード  29339900
絵表示(GHS) GHS hazard pictograms
注意喚起語
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H302 飲み込むと有害 急性毒性、経口 4 警告 GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 皮膚刺激 皮膚腐食性/刺激性 2 警告 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 強い眼刺激 眼に対する重篤な損傷性/眼刺激 性 2A 警告 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 呼吸器への刺激のおそれ 特定標的臓器毒性、単回暴露; 気道刺激性 3 警告 GHS hazard pictograms
注意書き
P264 取扱い後は皮膚をよく洗うこと。
P264 取扱い後は手や顔をよく洗うこと。
P270 この製品を使用する時に、飲食または喫煙をしないこ と。
P280 保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。
P301+P312 飲み込んだ場合:気分が悪い時は医師に連絡する こと。
P302+P352 皮膚に付着した場合:多量の水と石鹸で洗うこと。
P305+P351+P338 眼に入った場合:水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。
P321 特別な処置が必要である(このラベルの... を見よ)。
P330 口をすすぐこと。
P332+P313 皮膚刺激が生じた場合:医師の診断/手当てを受けるこ と。
P362 汚染された衣類を脱ぎ、再使用す場合には洗濯をすること。

葉酸メチルカルシウム塩 価格 もっと(16)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01CHDASB-00013517 葉酸メチルカルシウム塩
Methyl Folate Calcium Salt
151533-22-1 25mg ¥37800 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01CHDASB-00013517 葉酸メチルカルシウム塩
Methyl Folate Calcium Salt
151533-22-1 100mg ¥46400 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01MAS098097
Calcium (S)-2-(4-((((S)-2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)-4-carboxybutanoate
151533-22-1 1g ¥116800 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01MAS098097
Calcium (S)-2-(4-((((S)-2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)-4-carboxybutanoate
151533-22-1 5g ¥351900 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01MAS098097
Calcium (S)-2-(4-((((S)-2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)-4-carboxybutanoate
151533-22-1 25g ¥901600 2024-03-01 購入

葉酸メチルカルシウム塩 化学特性,用途語,生産方法

用途

強化剤

効能

葉酸補充薬

説明

Levomefolate calcium (L-5-MTHF-Ca) is a synthetic derivative of folic acid, the predominant, naturally occurring form of folate. L-5-methyltetrahydrofolate, also known as levomefolic acid, is the primary biologically active form of folate. It is involved in many important in vivo process including DNAreproduction, the cysteine cycle and the regulation of homocysteine. It is also the form found in circulation and transported across membranes into tissues and across the blood-brain barrier. It can be used for the treatment of major depressive disorder, cardiovascular disease and cancer. It can be used for the treatment of hyperhomocysteinemia regularly found in hemodialysis patients.

化学的特性

Off-White to Pale Yellow Solid

brand name

Products containing levomefolate calcium Brand name: L-Methylfolate Calcium
Multi-ingredient medications containing levomefolate calcium drospirenone/ethinyl estradiol/levomefolate calcium systemic Brand names: Beyaz, Tydemy, Safyral, Rajani

生物学の機能

Levomefolate calcium is the calcium salt of L-5-methyltetrahydrofolic acid, and a member of the folate group of vitamins (Vitamin B9). It is the coenzymated and most active form of folic acid, which performs many vital cellular functions, including DNA reproduction, cysteine cycle and homocysteine regulation. L-5-Methyltetrahydrofolate calcium is used as in dietary supplements and has been proposed for treatment of cardiovascular disease.

臨床応用

Folates are a class of water soluble compounds belonging to the Vitamin B complex which are essential for a number of metabolic functions, including processes involved in the development and metabolism of CNS and the production of DNA and RNA, primarily in infancy, adolescence and pregnancy.
Calcium Levomefolate is the active metabolic form of folates in the body.
Folate deficiency consequences can be as serious as birth defects (i.e. "spina bifida"), megaloblastic anaemia, and some types of depression.
Calcium Levomefolate can be the most effective treatment to remedy those deficiencies.
Calcium Levomefolate is formulated in many medical supplements for cases of folate deficiency or need for increased uptake; it is prescribed during pregnancy to prevent birth defects associated with CNS formation and functionality.
It is also the active ingredient in medicinal products prescribed for certain types of depression, disturbed behaviour and Mild Cognitive Impairment (MCI)

葉酸メチルカルシウム塩 上流と下流の製品情報

原材料

準備製品


葉酸メチルカルシウム塩 生産企業

Global( 393)Suppliers
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葉酸メチルカルシウム塩  スペクトルデータ(1HNMR)


151533-22-1(葉酸メチルカルシウム塩)キーワード:


  • 151533-22-1
  • (S)-2-(4-((((S)-2-AMino-5-Methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)Methyl)aMino)benzaMido)pentanedioic acid, calciuM salt
  • L-5- Methyl leucovorin
  • Calcium (S)-2-(4-((((S)-2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino
  • CALCIUML-5-METHYLTETRAHYDROFOLATE
  • (6S)-N-[4-(2-Amino-1,4,5,6,7,8,-hexahydro-5-methyl-4-oxo-6-pteridinylmethylamino)benzoyl]-L-glutaminsure, Calciumsalz (1:1)
  • METHYL FOLATE CALCIUM SALT(METAFOLIN)(P)
  • Levomefolate calcium
  • Levomefolate Calcium (Also See: M330135)
  • L-5-Methyltetrahydrofolate calciuM(L-5-MTHF-Ca)
  • N-[4-[[(2-Amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid calcium salt
  • Bodyfolin
  • LMCA
  • N-[4-[[[(6S)-2-AMino-3,4,5,6,7,8-hexahydro-5-Methyl-4-oxo-6-pteridinyl]Methyl]aMino]benzoyl]-L-glutaMic Acid CalciuM Salt
  • Nutrifolin
  • L-5-Methyletrahydrofolate calciuM
  • L-5-MTHF-Ca
  • Calcium (S)-2-(4-((((S)-2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)be
  • CalciuM (S)-2-(4-((((S)-2-aMino-5-Methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)Methyl)aMino)benzaMido)-4-carboxybutanoate
  • L-5-METHYLTETRAHYDROFOLATE CALCIUM 6S
  • L-5-Methyltetrahydrofolate calcium 99%
  • Deplin
  • calcium laevo-5-methyl tetrahydrofolate
  • Levomefolate (calcium salt)
  • Folic Acid Impurity 3
  • L-5-Methyletrahydrofolate calcium salt
  • 1-mcp1-methylcyclopropene
  • Calcium Levomefolate (L-5-Methyltetrahydrofolate Calcium Salt)
  • L-Glutamic acid, N-[4-[[[(6S)-2-amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-, calcium salt (1:1)
  • Calcium (6S)-5-methyl-tetrahydrofolate
  • LEVOMEFOLIC CALIUM
  • (6R,S)-5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, CA SALT
  • 葉酸メチルカルシウム塩
  • レボメフォラートカルシウム
  • レボメホリナートカルシウム
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