1-エチル-1H-ピラゾール-4-アミン HYDROCHLORIDE
1-エチル-1H-ピラゾール-4-アミン HYDROCHLORIDE 物理性質
- 沸点 :
- 238.6±13.0 °C(Predicted)
- 比重(密度) :
- 1.16±0.1 g/cm3(Predicted)
- 貯蔵温度 :
- under inert gas (nitrogen or Argon) at 2–8 °C
- 酸解離定数(Pka):
- 3.72±0.10(Predicted)
- CAS データベース:
- 876343-24-7
1-エチル-1H-ピラゾール-4-アミン HYDROCHLORIDE 価格
もっと(17)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01MAS019902 |
1-エチル-1H-ピラゾール-4-イルアミン
1-Ethyl-1H-pyrazol-4-ylamine |
876343-24-7 |
1g |
￥35400 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01MAS019902 |
1-エチル-1H-ピラゾール-4-イルアミン
1-Ethyl-1H-pyrazol-4-ylamine |
876343-24-7 |
5g |
￥107200 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBSS-3416 |
1-Ethyl-1H-pyrazol-4-amine |
876343-24-7 |
100g |
￥490000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01APOOR110643 |
4-Amino-1-ethyl-1H-pyrazole |
876343-24-7 |
1g |
￥28300 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBSS-3416 |
1-エチル-1H-ピラゾール-4-アミン
1-Ethyl-1h-pyrazol-4-amine |
876343-24-7 |
10g |
￥135000 |
2023-06-01 |
購入 |
1-エチル-1H-ピラゾール-4-アミン HYDROCHLORIDE 化学特性,用途語,生産方法
使用
1-ethyl-1H-pyrazol-4-amine can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
合成
General Procedure for the Synthesis of 4-Amino-l-N-alkylated-pyrazolesA solution of 4-nitropyrazole (300mg, 2.65mmol), potassium carbonate (2eq) and the alkylating reagent (l .leq) in acetonitrile (lOmL) was heated at 60??C for 18h. After cooling to rt the mixture was diluted with EtOAc and washed with water. The organic phase was collected, dried (MgS04) and concentrated in vacuo. The crude residue was dissolved in methanol (lOmL), palladium on carbon (50mg) was added and the reaction was stirred under a balloon of hydrogen for 18h. The resulting mixture was filtered through Celite and the filtrate concentrated in vacuo to give the desired product. Procedure B:Example 11: 2-((6-( 1 -Ethyl- 1 H-pyrazo 1-4-ylamino)- 1 H-pyrazo lo [3 ,4-d]pyrimidin- 1 -yl) methyl)benzonitrileThe following compound was made according to the procedure in Example 1, using 1-ethyl- lH-pyrazo 1-4-amine. 1 -ethyl- lH-pyrazol-4-amine was prepared by Procedure A using ethyl iodide as alkylating agent: 1H NMR (d6-DMSO) |? 9.94 (s, 1H), 8.94 (s, 1H), 8.10 (s, 2H), 7.91 (dd, 1H), 7.66 (td, 1H), 7.49-7.53 (m, 2H), 7.35-7.37 (m, 1H), 5.76 (s, 2H), 4.11 (q, 2H), 1.35 (t, 3H); LC-MS method B, (ES+) 345.1, RT = 8.58min.
1-エチル-1H-ピラゾール-4-アミン HYDROCHLORIDE 上流と下流の製品情報
原材料
準備製品
1-エチル-1H-ピラゾール-4-アミン HYDROCHLORIDE 生産企業
Global( 63)Suppliers
1-エチル-1H-ピラゾール-4-アミン HYDROCHLORIDE スペクトルデータ(1HNMR)
876343-24-7(1-エチル-1H-ピラゾール-4-アミン HYDROCHLORIDE)キーワード:
- 876343-24-7
- 1-ethyl-1H-pyrazol-4-amine
- 1-ethyl-1H-pyrazol-4-amine(SALTDATA: HCl)
- 1-ethyl-1H-pyrazol-4-amine hydrochloride
- 4-Amino-1-ethyl-1H-pyrazole
- 4-Amino-1-ethylpyrazole
- 1-ethylpyrazol-4-amine
- 1H-Pyrazol-4-amine, 1-ethyl-
- 1-エチル-1H-ピラゾール-4-アミン HYDROCHLORIDE
- 1-エチル-1H-ピラゾール-4-アミン
- 1-エチル-1H-ピラゾール-4-イルアミン
- 1-エチル-1H-ピラゾール-4-イルアミン HYDROCHLORIDE