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フェロコリネート

フェロコリネート 化学構造式
1336-80-7
CAS番号.
1336-80-7
化学名:
フェロコリネート
别名:
フェロコリネート
英語化学名:
CHOLINE CITRATE
英語别名:
CHOLINE CITRATE;TRICHOLINE CITRATE;choline ferric citrate;boxylato(4-))ferrate(1-);iron-choline citrate complex;2-HYDROXYETHYL-TRIMETHYL-AMMONIUM, 2-HYDROXYPROPANE-1,2,3-TRICARBOXYLATE;ethanaminium,2-hydroxy-n,n,n-trimethyl-,hydroxy(2-hydroxy-1,2,3-propanetricar
CBNumber:
CB1183829
化学式:
C11H21FeNO11
分子量:
399.13
MOL File:
1336-80-7.mol

フェロコリネート 物理性質

CAS データベース:
1336-80-7(CAS DataBase Reference)

安全性情報

WGK Germany  3

フェロコリネート 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

フェロコリネート 化学特性,用途語,生産方法

効能

貧血治療薬

Originator

Ferrolip,Flint,US,1953

使用

CHOLINE CITRATE is used in chemical reagents, organic intermediates, fine chemicals, pharmaceutical research and development.

Manufacturing Process

As described in US Patent 2,575,611, 107 parts of freshly prepared ferric hydroxide are added to 295 parts of choline dihydrogen citrate dissolved in 200 parts of distilled water and heated to approximately 80°C until a homogeneous solution occurs. The resulting reddish brown solution may be used as such or it may be dried by evaporating the water. The dried product is a reddish brown, amorphous solid presenting a glistening surface upon fracture. The dry product is somewhat hygroscopic and is freely soluble in water to give a stable solution. The following paragraph gives an alternative preparation.
One mol of tricholine citrate is dissolved in 6,000 ml of water and two mols of ferric citrate in solid form are added thereto. The reaction mass is then agitated until solution is effected, and until the reaction mass changes from brown to green. Water is removed either under vacuum, or as an azeotrope with benzene or toluene or by heating to a temperature of 110° to 115°C. There is thus obtained a gummy viscous mass which is treated with methanol, about five gallons, whereupon it solidifies, i.e., changes, into a green crystalline compound. Following the treatment with methanol, the mass is filtered and the green compound dried at about 70°C, according to US Patent 2,865,938.

Therapeutic Function

Hematinic

安全性プロファイル

Poison by intravenous and intraperitoneal routes. Mildly toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx. See also CHOLINE.

フェロコリネート 上流と下流の製品情報

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