ラタノプロスト

ラタノプロスト 価格 もっと(17)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01TRCL177280	ラタノプロスト Latanoprost	130209-82-4	50mg	￥299100	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01CAY16812	Latanoprost	130209-82-4	1mg	￥16000	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01CAY16812	Latanoprost	130209-82-4	5mg	￥46500	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01TRCL177280	ラタノプロスト Latanoprost	130209-82-4	5mg	￥48400	2023-06-01	購入
東京化成工業	L0262	ラタノプロスト >98.0%(HPLC) Latanoprost >98.0%(HPLC)	130209-82-4	10mg	￥25900	2023-06-01	購入

ラタノプロスト 化学特性,用途語,生産方法

外観

無色～うすい黄色透明液体

用途

PGF2α 誘導体です。プロス ラグンジン作用を示します。

効能

抗緑内障薬, プロスタグランジンF受容体作動薬

商品名

キサラタン (ファイザー)

説明

Xalatan was launched in Sweden, Switzerland and the US for the treatment of glaucoma. It can be synthesized, from the Corey lactone, using standard prostaglandin chemistry. Latanoprost is a PGF_2α, analog that is more lipophilic thus is better able to penetrate the cornea. The (15R)-diastereomer has only 10% of the activity compared to the (15S)-diastereomer. It is a selective FP receptor agonist with little or no effect on the other prostanoid receptors. The antiglaucoma effects are the result of reduced intraocular pressure arising by increasing uveoscleral outflow with little or no effect on trabeculo-canalicular aqueous outflow and no effect on retinal vasculation or permeability of the blood-aqueous barrier. The topical application is sufficient for a single daily dosage and is well tolerated with no detectible conjunctival hyperaemia.

化学的特性

Light Yellow Thick Oil

使用

Latanoprost is the isopropyl ester of 17-phenyl-13,14-dihydro prostaglandin F2α (17-phenyl-13,14-dihydro PGF2α). It is a prodrug form of the free acid, which is a potent agonist of the FP receptor in the eye. Latanoprost reduces intraocular pressure in glaucoma patients with few side effects. The EC50 value of latanoprost (tested as the free acid) for FP receptors is 3.6 nM.

定義

ChEBI: A prostaglandin Falpha that is the isopropyl ester prodrug of latanoprost free acid. Used in the treatment of open-angle glaucoma and ocular hypertension.

一般的な説明

Latanoprost (Xalatan) is available as a 0.005% sterileophthalmic solution in a 2.5-mL dispenser bottle.Latanoprost is also marketed as a combination ophthalmicproduct with the β-adrenergic blocking agent, timolol,which apparently enhances IOP-lowering by decreasing theproduction of aqueous humor. Cautions and side effects aresimilar to those for other ophthalmic prostanoids.

安全性プロファイル

A poison by ingestion and intravenous route. Human systemic effects. When heated to decomposition it emits acrid smoke and irritating vapors.

ラタノプロスト 上流と下流の製品情報

原材料

準備製品

ラタノプロスト 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	admin@guyunchem.com	China	616	58
Wuhan Quanjinci New Material Co.,Ltd.	+8615271838296	kyra@quanjinci.com	China	1532	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7786	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
Shanghai finete Pharmaceutical Co., Ltd.	+86-18221039705		CHINA	139	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60

130209-82-4(ラタノプロスト)キーワード:

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• 130209-82-4
• ISOPROPYL (5Z, 9A,11A,15R)-9,11,15-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROST-5Z-EN-1-OATE
• LATANOPROST
• [1R-[1α(Z)，2β(R^<*>^)，3α，5α]]-7-[3，5-Dihydroxy-2-(3-hydroxy-5-phenyl-pentyl)cyclopentyl]-5-heptenoic acid 1-methylethyl ester
• Xalata
• Isopropyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoat
• Latanopros
• Isopropyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoate
• Latanoprost ,98%
• 9ALPHA,11ALPHA,15R-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROST-
• cGMP Latanoprost
• propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate
• Latanoprost (50 mg)
• Latanoprost, >=99%
• Latanoprost API
• (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptanoic acid 1-methylethyl ester
• Isopropyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-en
• 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenyl-pentyl)-cyclopentyl]hept-5-enoate
• Propan-2-yl 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenyl-pentyl)-cyclopentyl]hept-5-enoate
• LATANOPROST WS & IMPURITY
• 9ALPHA,11ALPHA,15R-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROST-5Z-EN-1-OIC ACID, ISOPROPYL ESTER
• 9ALPHA, 11ALPHA, 15S-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROS-5Z-EN-1-OIC ACID, ISOPROPYL ESTER
• (1r-(1-alpha(z),2-beta(r*),3-alpha,5-alpha))--methylethyleste
• 7-(3,5-dihydroxy-2-(3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoicaci1
• phxa41
• xa41
• isopropyl (5z,9α,11α,15r)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinor-prost-5-en-1-oate
• LATANAPROST
• 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-, 1-methylethyl ester, (5Z)- (9CI)
• 5-Heptenoic acid, 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenylpentyl)cyclopentyl]-, 1-methylethyl ester, [1R-[1a(Z),2b(R*),3a,5a]]-
• Lata prostaglandin
• ラタノプロスト
• ラタノプロスト
• ラタノプロスト (JAN)
• (5Z,15R)-9α,11α,15-トリヒドロキシ-18,19,20-トリノル-17-フェニルプロスタ-5-エン-1-酸イソプロピル
• キサラタン
• (5Z)-7-[(1R,2R,3R,5S)-2-[(3R)-3-ヒドロキシ-5-フェニルペンチル]-3,5-ジヒドロキシシクロペンタン-1-イル]-5-ヘプテン酸イソプロピル
• 13,14-ジヒドロ-17-フェニル-18,19,20-トリノルPGF2αイソプロピル
• ラタノプロストPF
• (5Z,15R)-9α,11α,15-トリヒドロキシ-17-フェニル-18,19,20-トリノルプロスタ-5-エン-1-酸イソプロピル
• (5Z)-7-[(1R)-2β-[(3R)-3-ヒドロキシ-5-フェニルペンチル]-3α,5α-ジヒドロキシシクロペンタン-1α-イル]-5-ヘプテン酸イソプロピル
• (5Z,9S,11R,15R)-9,11,15-トリヒドロキシ-17-フェニル-18,19,20-トリノルプロスタ-5-エン-1-酸1-メチルエチル
• (Z)-7-[(1R,2R,3R,5S)-3,5-ジヒドロキシ-2-[(3R)-3-ヒドロキシ-5-フェニルペンチル]シクロペンチル]-5-ヘプテン酸イソプロピル
• プロパン-2-イル (5Z)-7-[(1R,2R,3R,5S)-3,5-ジヒドロキシ-2-[(3R)-3-ヒドロキシ-5-フェニルペンチル]シクロペンチル]ヘプタ-5-エノアート