ビタミンE 化学特性,用途語,生産方法
定義
本品は、ビタミンEであり、次の化学式で表される。
化粧品の成分用途
閉塞剤、皮膚コンディショニング剤、酸化防止剤、香料
物理的性質
Vitamin E has demonstrated some success in the treatment of yellow nail syndrome when taken orally (600 EU to 1200 EU daily) for several months. Topically-applied vitamin E has also shown significant improvement in symptoms of yellow nail syndrome, as well as increased nail growth rates after six months.
使用
Vitamin E supplement.
適応症
Vitamin E is a potent antioxidant that is capable of protecting
polyunsaturated fatty acids from oxidative
breakdown.This vitamin also functions to enhance vitamin
A use.Although several other physiological actions
have been suggested, to date no unifying concept exists
to explain these actions. Vitamin E (α-tocopherol) is
found in a variety of foodstuffs, the richest sources being
plant oils, including wheat germ and rice, and the
lipids of green leaves.
利点
Vitamin E is a fat-soluble nutrient found in many foods. It is the most abundant antioxidant in the skin and the most important lipid-soluble, membrane-bound antioxidant in the body. The body also needs vitamin E to boost its immune system so that it can fight off invading bacteria and viruses. It helps to widen blood vessels and keep blood from clotting within them. In addition, cells use vitamin E to interact with each other and to carry out many important functions.
臨床応用
Deficiency of vitamin E is characterized by low
serum tocopherol levels and a positive hydrogen peroxide
hemolysis test.This deficiency is believed to occur in
patients with biliary, pancreatic, or intestinal disease
that is characterized by excessive steatorrhea. Premature
infants with a high intake of fatty acids exhibit a
deficiency syndrome characterized by edema, anemia,
and low tocopherol levels.This condition is reversed by
giving vitamin E.
副作用
Prolonged administration of large dosages of vitamin
E may result in muscle weakness, fatigue, headache,
and nausea.This toxicity can be reversed by discontinuing
the large-dose supplementation.
毒性学
α-Tocopherol is known as vitamin E and exists in many kind of plants, especially in lettuce and alfalfa. Its color changes from yellow to dark brown when exposed to sunlight. Natural vegetable oils are not readily oxidized due to the presence of
tocopherol. During refining processes, however, tocopherol may be removed
from oils; consequently, refined vegetable oils can become unstable toward
oxidation. In one experiment, vitamin E appeared to be relatively innocuous,
having been given to patients for months both orally and parenterally
at a dosage level of 300 mg/day without any observed ill effects. However,
in another experiment, 6 out of 13 patients given similar doses complained
of headache, nausea, fatigue, dizziness, and blurred vision.
Although the chronic toxicity of vitamin E has not been thoroughly
studied, WHO recommends 2 mg/kg/day as the maximum daily dose.
ビタミンE 上流と下流の製品情報
原材料
準備製品