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(E/Z)-BCI塩酸塩 塩酸塩

(E/Z)-BCI塩酸塩 塩酸塩 化学構造式
95130-23-7
CAS番号.
95130-23-7
化学名:
(E/Z)-BCI塩酸塩 塩酸塩
别名:
(E/Z)-BCI塩酸塩 塩酸塩
英語名:
NSC 150117 hydrochloride
英語别名:
(E/Z)-BCI;BCI (hydrochloride);(E)-BCI hydrochloride;(E/Z)-BCI hydrochloride;NSC 150117 hydrochloride;BCI hydrochloride - NSC 150117 hydrochloride;(2Z)-2-benzylidene-3-(cyclohexylamino)-3H-inden-1-one;2-benzylidene-3-(cyclohexylamino)-1-Indanone hydrochloride;(E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one;3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-1Hinden-1-one
CBNumber:
CB12756032
化学式:
C22H24ClNO
分子量:
353.885
MOL File:
95130-23-7.mol
MSDS File:
SDS

(E/Z)-BCI塩酸塩 塩酸塩 物理性質

貯蔵温度 :
2-8°C
溶解性:
DMSO：可溶10mg/mL、透明
外見 :
粉
色:
白からベージュ

安全性情報

WGK Germany  3

(E/Z)-BCI塩酸塩 塩酸塩 価格 もっと(2)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
Sigma-Aldrich Japan B4313 (E/Z)-BCI塩酸塩 塩酸塩 ≥98% (HPLC)
(E/Z)-BCI hydrochloride ≥98% (HPLC)		 95130-23-7 5mg ￥50400 2024-03-01 購入
Sigma-Aldrich Japan B4313 (E/Z)-BCI塩酸塩 塩酸塩 ≥98% (HPLC)
(E/Z)-BCI hydrochloride ≥98% (HPLC)		 95130-23-7 25mg ￥122000 2024-03-01 購入

(E/Z)-BCI塩酸塩 塩酸塩 化学特性,用途語,生産方法

使用

(E/Z)-BCI hydrochloride has been used:
  • to evaluate the role of the Duox-H2O2-Dusp6 derepression signaling pathway in heart regeneration
  • as an MKP-1 inhibitor to investigate the role of MKP-1 on bexarotent-induced effects
  • as a dual specificity phosphatase 6 (DUSP6) inhibitor to study its effects on the proliferation of SKOV3 cells

Biochem/physiol Actions

BCI is an allosteric inhibitor of Dusp6 that acts within the phosphatase domain to prevent the catalytic stimulation of phosphatase activity induced by ERK2 substrate binding. BCI also hyperactivates FGF signaling, since Dusp6 functions as a feedback regulator of FGF signaling.

(E/Z)-BCI塩酸塩 塩酸塩 上流と下流の製品情報

原材料

準備製品

(E/Z)-BCI塩酸塩 塩酸塩 生産企業

Global( 16)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 19892 58
Aladdin Scientific 		+1-833-552-7181
sales@aladdinsci.com United States 52927 58
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51471 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9709 58
Shanghai Han-Xiang Chemical Co., Ltd. 15971444841
 amber@biochempartner.com China 3063 58
Changzhou Chenhong Biotechnology Co., Ltd. 0519-85788828 13775037613
 sales@chemrenpharm.com China 3538 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11289 58
Shanghai hongqu biomedical technology co. LTD 88888888888
 hongquchem@qq.com China 5132 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223
 psaitong@jm-bio.com China 29834 58
TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 24131 58
  • 95130-23-7
  • (E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one
  • (E/Z)-BCI hydrochloride
  • 2-benzylidene-3-(cyclohexylamino)-1-Indanone hydrochloride
  • 3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-1Hinden-1-one
  • NSC 150117 hydrochloride
  • BCI (hydrochloride)
  • (E/Z)-BCI
  • BCI hydrochloride - NSC 150117 hydrochloride
  • (2Z)-2-benzylidene-3-(cyclohexylamino)-3H-inden-1-one
  • (E)-BCI hydrochloride
  • (E/Z)-BCI塩酸塩 塩酸塩
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