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タゴシッド

タゴシッド 化学構造式
61036-62-2
CAS番号.
61036-62-2
化学名:
タゴシッド
别名:
テイコプラニン;テイコマイシン;タゴシッド
英語化学名:
Teicoplanin
英語别名:
TEIC;8327a;Tagocid;Ticoplanin;TEICOPLANIN;Teocoplanin;teichomycin;Telcoplanin;Telicoplanin;antibiotic8327a
CBNumber:
CB1308141
化学式:
C78H77Cl2N8O32R
分子量:
1709.39
MOL File:
61036-62-2.mol

タゴシッド 物理性質

RTECS 番号:
WY1559000
貯蔵温度 :
2-8°C
溶解性:
H2O: soluble10mg/mL
外見 :
powder
色:
white to faint yellow
水溶解度 :
Sparingly soluble in water
CAS データベース:
61036-62-2

安全性情報

WGK Germany  3

タゴシッド 価格 もっと(6)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01BVI1756-100
Teicoplanin
61036-62-2 100mg ¥15600 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01BVI1756-1G
Teicoplanin
61036-62-2 1g ¥107900 2018-12-26 購入
Sigma-Aldrich Japan PHR1811 Pharmaceutical Secondary Standard; Certified Reference Material
Teicoplanin Pharmaceutical Secondary Standard; Certified Reference Material
61036-62-2 100mg ¥21800 2018-12-25 購入
Sigma-Aldrich Japan T0578 テイコプラニン
Teicoplanin
61036-62-2 100mg ¥27200 2018-12-25 購入
Sigma-Aldrich Japan Y0001102 European Pharmacopoeia (EP) Reference Standard
Teicoplanin European Pharmacopoeia (EP) Reference Standard
61036-62-2 y0001102 ¥33600 2018-12-25 購入

タゴシッド 化学特性,用途語,生産方法

説明

Teicoplanin is a new antibiotic, the second glycopeptide to be developed in over 30 years. Compared with vancomycin, the only such agent currently available, teicoplanin is equiefficacious, and has milder side-effects and a longer half-life, allowing once-daily dosing and bolus injection. Teicoplanin is claimed to have an overall cure rate of 92% in infections involving skin, joint and bone, endocaditis and septicemia.

化学的特性

Yellowish, amorphous powder.

使用

anticonvulsant, antipsychotic

使用

Teicoplanin complex is family of closely related metabolites produced by Actinoplanes teichomyceticus. Teicoplanin complex possesses potent broad spectrum antibiotic activity against Gram positive bacteria, including MRSA and E. faecalis. The metabolites share a common glycopeptide core (teicoplanin A-3) on which a family of fatty acids varying in length, degree of saturation and branching are linked as amides through one of the aminoglycoside moieties. The major component of the complex is teicoplanin A2 which itself has five major components (teicoplanin A2-1 to A2-5) and four minor components (teicoplanin RS-1 to RS-4).

使用

antidepressant

brand name

Targocid

一般的な説明

Teicoplanin (Teichomycin A2, Targocid) is a mixture offive closely related glycopeptide antibiotics produced bythe actinomycete Actinoplanes teichomyceticus. The teicoplanin factors differ only in the acyl group inthe northernmost of two glucosamines glycosidicallylinked to the cyclic peptide aglycone. Another sugar, Dmannose,is common to all of the teicoplanins. Thestructures of the teicoplanin factors were determined independentlyby a combination of chemical degradationand spectroscopic methods in three different groupsin 1984.
The teicoplanin complex is similar to vancomycin structurallyand microbiologically but has unique physical propertiesthat contribute some potentially useful advantages.While retaining excellent water solubility, teicoplanin has significantlygreater lipid solubility than vancomycin. Thus, teicoplaninis distributed rapidly into tissues and penetratesphagocytes well. The complex has a long elimination halflife,ranging from 40 to 70 hours, resulting from a combinationof slow tissue release and a high fraction of protein bindingin the plasma (~90%). Unlike vancomycin, teicoplanin isnot irritating to tissues and may be administered by intramuscularor intravenous injection. Because of its long half-life, teicoplaninmay be administered on a once-a-day dosing schedule.Orally administered teicoplanin is not absorbedsignificantly and is recovered 40% unchanged in the feces.
Teicoplanin exhibits excellent antibacterial activity againstGram-positive organisms, including staphylococci, streptococci,enterococci, Clostridium and Corynebacterium spp.,Propionibacterium acnes, and L. monocytogenes. It is not activeagainst Gram-negative organisms, including Neisseriaand Mycobacterium spp. Teicoplanin impairs bacterial cellwall synthesis by complexing with the terminal D-alanine-Dalaninedipeptide of the peptidoglycan, thus preventing crosslinkingin a manner entirely analogous to the action ofvancomycin.

タゴシッド 上流と下流の製品情報

原材料

準備製品


タゴシッド 生産企業

Global( 170)Suppliers
名前 電話番号 ファックス番号 電子メール 国籍 製品カタログ 優位度
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19954 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 bruce@xrdchem.cn CHINA 552 55
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24118 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8430 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930501651
breeduan@crovellbio.com CHINA 898 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19997 58
Hebei Chisure Biotechnology Co., Ltd.
+8613292893290
+8613292893290 Nancy@SpeedGainpharma.com CHINA 590 58

61036-62-2(タゴシッド)キーワード:


  • 61036-62-2
  • TEICOPLANIN
  • 8327a
  • antibiotic8327a
  • teichomycin
  • Teocoplanin
  • Telicoplanin
  • Tagocid
  • TEIC
  • Teicoplanin sterile
  • lyophilised teicoplanin
  • TEICOPLANIN, JP
  • TeicoplaninSodium
  • Telcoplanin,Tecoplanin
  • TEICOPLANIN(PATENTED)
  • TazobactuM SodiuM+Piperacillin SodiuM
  • TEICOPLANIN [A(2-1) shown]
  • TeichoMycin, Tecoplanin, Targocid, TeicoMid, 8327A, DL 507IT, L 12507, MDL 507, MW 1900
  • Teicoplanin coMplex
  • Ticoplanin
  • Telcoplanin
  • Teicoplanin Complex (Tecoplanin)
  • Teicomycin,、Targocid
  • テイコプラニン
  • テイコマイシン
  • タゴシッド
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