4-ニトロ-1,2-フェニレンジアミン 化学特性,用途語,生産方法
外観
黄色～くすんだ黄色～暗い赤色粉末～結晶
溶解性
水に溶けやすく、エタノール及びアセトンにやや溶けにくい。
用途
エームステストにおける陽性対象物質、有機合成原料。
化学的特性
This substance is an orange-red powder that can be dissolved in ethanol, acetone, and hydrochloric acid solution, but is not soluble in water.
主な応用
4-Nitro-1,2-phenylenediamine is a hair dye constituent with potential mutagenic activity. It is used in oxidation hair dye formulations at a maximum concentration of 1.0 %, which after mixing typically in a 1:1 ratio with hydrogen peroxide just prior to use, corresponds to a concentration of 0.5% upon application.
定義
ChEBI: 4-nitro-1,2-phenylenediamine is the primary amino compound that is 1,2-phenylenediamine (o-phenylenediamine) substituted at the 4- (para-) position by a nitro group. It is a primary amino compound and a C-nitro compound. It is functionally related to a 1,2-phenylenediamine.
調製方法
Commercial production of 4-nitro-o-PDA was first reported
in the United States in 1946. Two U.S. companies were
reported to produce undisclosed amounts of the chemical in
1975. U.S. imports of 4-nitro-o-PDA were reported to be
about 1900 kg in 1973 and 1100 kg in 1975. 4-Nitro-o-PDAis
used in fur dyes, inks, and semipermanent yellow hair
coloring formulations requiring a yellow color component
that does not involve the use of hydrogen peroxide in the
color development.
Occupational exposure to 4-nitro-o-PDA may occur
through inhalation and dermal contact with this compound
at workplaces where p-PDA is produced or used. The general
population may be exposed to the compound via dermal
contact, primarily through the use of hair dyes containing
this compound.
一般的な説明
4-nitro-o-phenylenediamine appears as dark red needles or red solid.
空気と水の反応
Insoluble in water.
反応プロフィール
4-Nitro-o-phenylenediamine is incompatible with strong oxidizing agents, strong acids, strong reducing agents, acid chlorides and acid anhydrides.
火災危険
Flash point data for 4-Nitro-o-phenylenediamine are not available; however, 4-Nitro-o-phenylenediamine is probably combustible.
安全性プロファイル
Moderately toxic by ingestion. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. Questionable carcinogen. When heated to decomposition it emits toxic fumes of NOx,.
純化方法
Crystallise the diamine from water. [Beilstein 13 IV 75.]
4-ニトロ-1,2-フェニレンジアミン 上流と下流の製品情報
原材料
準備製品