2-ヘキサノン 化学特性,用途語,生産方法
外観
無色～わずかにうすい黄色, 澄明の液体
溶解性
水に可溶, アルコール, エーテルに易溶。エタノール及びアセトンに溶けやすく、水にわずかに溶ける。
用途
溶剤、香料 (化学工業日報社)
説明
2-Hexanone has been used as a solvent for both cellulose- and
resin-based coating systems. In the early 1970s, a number of
workers in the print department of a coated fabrics plant
developed severe peripheral neuropathy from an unknown
cause. In search of an etiological agent, and in the absence of
other neurotoxicants, 2-hexanone was implicated as it was
recently substituted for methyl isobutyl ketone in the
manufacturing process. Similar observations in workers
exposed to 2-hexanone may have resulted in the decline in
production and use in the United States.
化学的特性
2-Hexanone is a colorless to pale yellow liquid with a sharp odor. It dissolves very easily in
water and is miscible in ethanol, methanol, and benzene. 2-Hexanone evaporates easily into
the air as a vapor. It is stable, flammable, and incompatible with oxidizing agents, strong bases,
and reducing agents. 2-Hexanone is a waste product of wood pulping, coal gasifi cation, and
oil shale operations. Formerly, 2-hexanone was in use as a paint and paint thinner with other
chemical substances, and to dissolve oils and waxes.and is used as a solvent and organic syn-
thesis intermediates. However, the industrial uses of 2-hexanone is now very much restricted.
物理的性質
Clear, colorless to pale yellow, flammable liquid with an odor resembling acetone and 2-butanone.
Nagata and Takeuchi (1990) reported an odor threshold concentration of 24 ppb
v. Amoore and
Hautala (1983) reported odor threshold concentrations of 250 μg/L and 76 ppb
v in water and air,
respectively.
使用
2-Hexanone is used in various organic chemical syntheses. It is used in the synthesis of (+/-)-monomorine. It is also used in the preparation of alcohols by transfer hydrogenation of ketones.
調製方法
MnBK can be produced by a reaction between acetic acid and ethylene under pressure MnBK can be produced by a reaction between acetic acid and ethylene under pressure.
一般的な説明
A clear colorless liquid. Flash point 95°F. Less dense than water. Vapors heavier than air.
空気と水の反応
Highly flammable. Slightly soluble in water.
反応プロフィール
2-Hexanone is incompatible with oxidizing agents. 2-Hexanone may also react with strong bases and reducing agents.
危険性
Flammable, moderate fire risk, explosive limits 1.2–8% in air. Irritant to eyes and
mucous membranes, narcotic in high concentration,
absorbed by skin. Causes peripheral neuropathy and
testicular damage.
健康ハザード
Inhalation of high concentrations of vapor may result in narcosis; peripheral neuropathy may develop. Ingestion of large amounts may cause some systemic injury. Contact with eyes causes mild to moderate irritation. Liquid irritates skin; prolonged or repeated contact may cause defatting of the skin with resultant dermatitis.
火災危険
2-Hexanone is flammable.
職業ばく露
The material is used as a solvent
環境運命予測
Biological. Using the BOD technique to measure biodegradation, the mean 5-d BOD value (mM
BOD/mM 2-hexanone) and ThOD were 5.22 and 61.4%, respectively (Vaishnav et al., 1987).
Photolytic. A second-order photooxidation rate constant of 8.97 x 10
-12 cm
3/molecule?sec for the
reaction of 2-hexanone and OH radicals in the atmosphere at 299 K was reported by Atkinson
(1985).
Chemical/Physical. 2-Hexanone will not hydrolyze because it has no hydrolyzable functional
group (Kollig, 1995).
貯蔵
2-Hexanone should be kept stored in a tightly closed container, in a cool, dry place, away
from sources of ignition.
輸送方法
UN1224 Ketones, liquid, n.o.s., Hazard Class: 3;
Labels: 3-Flammable liquid, Technical Name Required
廃棄物の処理
Dissolve or mix the
material with a combustible solvent and burn in a chemical
incinerator equipped with an afterburner and scrubber.
All federal, state, and local environmental regulations
must be observed.
予防処置
Occupational workers should be careful when using and handling 2-hexanone. Workers
should wash thoroughly after handling the chemical substance. Workers should avoid contact of 2-hexanone with the eyes, skin, and clothing and also avoid contact with heat,
sparks, and flame.
2-ヘキサノン 上流と下流の製品情報
原材料
準備製品