3β,23-ジヒドロキシルパ-20(29)-エン-28-酸 化学特性,用途語,生産方法
説明
23-hydroxy Betulinic acid is a triterpenoid that has been found in
P. chinensis and has anticancer activity. It inhibits proliferation of K562, B16, and HeLa cells (IC
50s = 39.9, 78.5, and 80 μM, respectively), as well as human umbilical vein endothelial cells (HUVECs; IC
50 = 94.8 μM). It halts the cell cycle at the S phase and induces apoptosis in K562 cells in a concentration-dependent manner with a loss of the mitochondrial membrane potential and an increase in Bax and cytochrome C protein levels.
使用
23-Hydroxybetulinic Acid is a potential cytoxic agent in the treatment of cancer. Apoptotic effect. Antiproliferative.
3β,23-ジヒドロキシルパ-20(29)-エン-28-酸 上流と下流の製品情報
原材料
準備製品