ChemicalBook
Chinese english Germany Korea

塩化ベンジル

塩化ベンジル 化学構造式
100-44-7
CAS番号.
100-44-7
化学名:
塩化ベンジル
别名:
塩化ベンジル;(クロロメチル)ベンゼン;ベンジルクロリド;1-クロロメチルベンゼン;クロロメチルベンゼン;1-(クロロメチル)ベンゼン;クロロ(フェニル)メタン;α-クロロトルエン;フェニルクロロメタン;ω-クロロトルエン;フェニル(クロロ)メタン;クロロフェニルメタン;化ベンジル;塩化ベンジル 塩化物;Α-クロロトルエン標準品;ベンジル=クロリド (別名 塩化ベンジル);ベンジル=クロリド(別名塩化ベンジル);Α‐クロロトルエン標準品;ベンジルクロリド 塩化ベンジル;ベンジルクロリド STANDARD
英語化学名:
Benzyl chloride
英語别名:
Bzl-Cl;Benzile;Benzyle;NSC 8043;ai3-15518;C6H5CH2Cl;NCI-C06360;Benzylchlorid;tolylchloride;α-Chlortoluol
CBNumber:
CB1852583
化学式:
C7H7Cl
分子量:
126.58
MOL File:
100-44-7.mol

塩化ベンジル 物理性質

融点 :
-39 °C
沸点 :
179 °C
比重(密度) :
1.1 g/mL at 25 °C(lit.)
蒸気密度:
4.36 (vs air)
蒸気圧:
10.3 mm Hg ( 60 °C)
屈折率 :
n20/D 1.538(lit.)
闪点 :
165 °F
貯蔵温度 :
0-6°C
溶解性:
soluble0.46g/L at 30°C (Decomposes in contact with water)
外見 :
Liquid
色:
Clear colorless to slightly yellow
臭い (Odor):
Pungent, irritating.
爆発限界(explosive limit):
1.1-14%(V)
水溶解度 :
0.3 g/L (20 ºC)
Merck :
14,1129
BRN :
471308
Henry's Law Constant:
(x 10-4 atm?m3/mol): 3.57 at 20.00 °C (inert gas stripping, Hovorka and Dohnal, 1997)
暴露限界値:
TLV-TWA 1 ppm (~5mg/m3) (ACGIH, MSHA, and OSHA); IDLH 10 ppm (NIOSH); carcinogenicity: Animal Limited Evidence, Human Inadequate Evidence (IARC).
安定性::
Unstable - inhibitors such as propylene oxide or trimethylamine are usually added to prevent polymerization. Combustible. Incompatible with strong oxidizing agents, water, acids, most common metals, dimethyl sulfoxide. Above flash point vapour-air mixtures are explosive within the limits noted above. Contact with water produces toxic fumes.
InChIKey:
KCXMKQUNVWSEMD-UHFFFAOYSA-N
CAS データベース:
100-44-7(CAS DataBase Reference)
NISTの化学物質情報:
Benzyl chloride(100-44-7)
EPAの化学物質情報:
Benzene, (chloromethyl)-(100-44-7)
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
主な危険性  T,T+
Rフレーズ  45-22-23-37/38-41-48/22-43-26-46
Sフレーズ  53-45-36/37/39-28-26-36/37
RIDADR  UN 1738 6.1/PG 2
WGK Germany  3
RTECS 番号 XS8925000
8-19
自然発火温度 585 °C
TSCA  Yes
国連危険物分類  6.1
容器等級  II
HSコード  29039990
有毒物質データの 100-44-7(Hazardous Substances Data)
毒性 LD50 orally in Rabbit: 440 mg/kg
消防法 危険物第4類第二石油類(非水溶性)
化審法 (3)-39, (3)-102 優先評価化学物質
安衛法 変異原性物質
PRTR法 第一種指定化学物質
毒劇物取締法 毒物
絵表示(GHS)
注意喚起語 Danger
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H227 引火性液体 引火性液体 4 警告 P210, P280, P370+P378, P403+P235,P501
H301 飲み込むと有毒 急性毒性、経口 3 危険 P264, P270, P301+P310, P321, P330,P405, P501
H302 飲み込むと有害 急性毒性、経口 4 警告 P264, P270, P301+P312, P330, P501
H314 重篤な皮膚の薬傷?眼の損傷 皮膚腐食性/刺激性 1A, B, C 危険 P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H315 皮膚刺激 皮膚腐食性/刺激性 2 警告 P264, P280, P302+P352, P321,P332+P313, P362
H317 アレルギー性皮膚反応を起こすおそれ 感作性、皮膚 1 警告 P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H318 重篤な眼の損傷 眼に対する重篤な損傷性/眼刺激 性 1 危険 P280, P305+P351+P338, P310
H330 吸入すると生命に危険 急性毒性、吸入 1, 2 危険 P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H331 吸入すると有毒 急性毒性、吸入 3 危険 P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H335 呼吸器への刺激のおそれ 特定標的臓器毒性、単回暴露; 気道刺激性 3 警告
H340 遺伝性疾患のおそれ 生殖細胞変異原性 1A, 1B 危険
H350 発がんのおそれ 発がん性 1A, 1B 危険
H370 臓器の障害 特定標的臓器有害性、単回暴露 1 危険 P260, P264, P270, P307+P311, P321,P405, P501
H372 長期にわたる、または反復暴露により臓器の障 害 特定標的臓器有害性、単回暴露 1 危険 P260, P264, P270, P314, P501
H373 長期にわたる、または反復暴露により臓器の障 害のおそれ 特定標的臓器有害性、単回暴露 2 警告 P260, P314, P501
H400 水生生物に強い毒性 水生環境有害性、急性毒性 1 警告 P273, P391, P501
注意書き
P202 全ての安全注意を読み理解するまで取り扱わないこ と。
P210 熱/火花/裸火/高温のもののような着火源から遠ざ けること。-禁煙。
P264 取扱い後は皮膚をよく洗うこと。
P264 取扱い後は手や顔をよく洗うこと。
P270 この製品を使用する時に、飲食または喫煙をしないこ と。
P271 屋外または換気の良い場所でのみ使用すること。
P273 環境への放出を避けること。
P284 呼吸用保護具を着用すること。
P307+P311 暴露した場合:医師に連絡すること。
P391 漏出物を回収すること。

塩化ベンジル 価格 もっと(22)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01ACSM-8010-01 ベンジルクロリド
Benzyl chloride, 0.2 mg/mL in MeOH
100-44-7 1mL ¥3700 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01ACSAS-E0169 ベンジルクロリド Standard
Benzyl chloride Standard, 5.0 mg/mL in Acetonitrile
100-44-7 1mL ¥11800 2018-12-26 購入
東京化成工業 B0412 ベンジルクロリド >99.0%(GC)
Benzyl Chloride (stabilized with ε-Caprolactam) >99.0%(GC)
100-44-7 500g ¥2400 2018-12-04 購入
東京化成工業 B0412 ベンジルクロリド >99.0%(GC)
Benzyl Chloride (stabilized with ε-Caprolactam) >99.0%(GC)
100-44-7 25g ¥1700 2018-12-04 購入
関東化学株式会社(KANTO) 04152-01 塩化ベンジル >96.0%(GC)
Benzyl chloride >96.0%(GC)
100-44-7 500mL ¥1900 2018-12-13 購入

塩化ベンジル 化学特性,用途語,生産方法

外観

無色~わずかにうすい黄色, 澄明の液体

溶解性

エタノール及びアセトンに極めて溶けやすく、水にほとんど溶けない。

用途

有機合成、染料及び染料中間体原料

用途

農薬?ゴム薬品原料、染料?医薬中間体原料

化学的特性

Colorless to yellow liquid

化学的特性

Benzyl chloride is a colorless to s lightly yellow liquid with a strong, unpleasant, irritating odor. The Odor Threshold is 0.05 ppm.

物理的性質

Colorless to pale yellowish-brown liquid with a pungent, aromatic, irritating odor. Odor threshold concentration is 47 ppbv (Leonardos et al., 1969). Katz and Talbert (1930) reported an experimental detection odor threshold concentration of 210 μg/m3 (41 ppbv).

使用

Benzyl chloride is used in the manufacture ofdyes, artificial resins, tanning agents, phar maceuticals, plasticizers, perfumes, lubri cants, and miscellaneous benyl compounds.

使用

manufacture of benzyl Compounds, perfumes, pharmaceutical products, dyes, synthetic tannins, artificial resins.

使用

An intermediate in the preparation of phenylacetic acid (precursor to phamaceuticals). Also a precursor molecule to benzyl esters which are used as plasticizer, flavorants, and perfumes.

定義

ChEBI: A member of the class of benzyl chlorides that is toluene substituted on the alpha-carbon with chlorine.

一般的な説明

A colorless liquid with an irritating odor. Toxic by inhalation and skin absorption. Flash point 153°F. Slightly soluble in water. Corrosive to metals and tissue. A lachrymator. Density 9.2 lb /gal.

空気と水の反応

A lachrymator. Slightly soluble in water.

反応プロフィール

Halogenated aliphatic compounds, such as Benzyl chloride, are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

危険性

Highly toxic, intense eye and skin irritant. A lachrymator. Upper respiratory tract irritant. Prob- able carcinogen.

健康ハザード

Intensely irritating to skin, eyes, and mucous membranes. Highly toxic; may cause death or permanent injury after very short exposure to small quantities. Has been listed as a direct-acting or primary carcinogen. Large doses cause central nervous system depression.

健康ハザード

Benzyl chloride is a corrosive liquid. Con tact with the eyes can cause corneal injury.Exposure to its vapors can produce intenseirritation of the eyes, nose, and throat. Highconcentrations may cause lung edema anddepression of the central nervous system.Flury and Zernik (1931) stated that exposureto 16 ppm for 1 minute was intolerable tohumans. The LC50 values for a 2-hour expo sure in mice and rats are 80 and 150 ppm,respectively. The subcutaneous LD50 valuein rats is 1000 mg/kg (NIOSH 1986).
Benzyl chloride tested positive to thehistidine reversion–Ames test for mutagenic ity. Subcutaneous administration of this com pound in laboratory animals caused tumors atthe site of application.

火災危険

Benzyl chloride burns but does not ignite readily. Benzyl chloride may ignite combustibles. When heated to decomposition, Benzyl chloride emits toxic and corrosive fumes. Some organic chlorides decompose to yield phosgene. Incompatible with active metals such as copper, aluminum, magnesium, iron, zinc, and tin and keep from strong oxidizing agents. Avoid contact with acids or acid fumes. Keep separate from oxidizing materials. May become unstable at elevated temperatures and pressures; may react with water resulting in some nonviolent release of energy. Polymerizes with evolution of heat and hydrogen chloride when in contact with all common metals except nickel and lead.

化学反応性

Reactivity with Water Undergoes slow hydrolysis, liberating hydrogen chloride (hydrochloric acid); Reactivity with Common Materials: Decomposes rapidly in the presence of all common metals (with the exception of nickel and lead), liberating heat and hydrogen chloride; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Rinse with sodium bicarbonate or lime solution; Polymerization: Polymerizes with evolution of heat and hydrogen chloride when in contact with all common metals except nickel and lead; Inhibitor of Polymerization: Triethylamine, propylene oxide or sodium carbonate.

職業ばく露

Used as an intermediate and as an irritant gas in chemical warfare. In contrast to phenyl halides, benzyl halides are very reactive. Benzyl chloride is used in production of benzal chloride, benzyl alcohol, and benzaldehyde. Industrial usage includes the manufacture of plastics, dyes, synthetic tannins, perfumes and resins. It is used in the manufacture of many pharmaceuticals. Suggested uses of benzyl chloride include: the vulcanization of fluororubbers and the benzylation of phenol and its derivatives for the production of possible disinfectants.

Source

As of October 1996, benzyl chloride was listed for regulation but no MCLGs or MCLs have been proposed (U.S. EPA, 1996).
Reported as an impurity (≤ 0.05 wt %) in 98.5 wt % benzyl mercpatan (Chevron Phillips, April 2005).

環境運命予測

Biological. When incubated with raw sewage and raw sewage acclimated with hydrocarbons, benzyl chloride degraded forming nonchlorinated products (Jacobson and Alexander, 1981).
Chemical/Physical. Anticipated products from the reaction of benzyl chloride with ozone or OH radicals in the atmosphere are chloromethyl phenols, benzaldehyde and chlorine radicals (Cupitt, 1980).
Slowly hydrolyzes in water forming HCl and benzyl alcohol. The estimated hydrolysis half-life in water at 25 °C and pH 7 is 15 h (Mabey and Mill, 1978). The hydrolysis rate constant for benzyl chloride at pH 7 and 59.2 °C was determined to be 0.0204/min, resulting in a half-life of 34 min (Ellington et al., 1986).
May polymerize in contact with metals except nickel and lead (NIOSH, 1997).
When heated to decomposition, hydrogen chloride gas may be released (CHRIS, 1984).

輸送方法

UN1738 Benzyl chloride, Hazard class: 6.1; Labels: 6.1—Poisonous materials, 8—Corrosive material.

純化方法

Dry it with MgSO4 or CaSO4, or reflux it with fresh Ca turnings, then fractionally distil it under reduced pressure, collecting the middle fraction and storing it over CaH2 or P2O5. It has also been purified by passage through a column of alumina. Alternatively it is dried over MgSO4 and distilled in a vacuum. The middle fraction is degassed by several freeze-thaw cycles and then fractionated in an 'isolated fractionating column' (which has been evacuated and sealed off at ~10-6 mm) over a steam bath. The middle fraction is retained. The final samples are distilled in a vacuum from this sample and again retaining the middle fraction. The purity is >99.9% (no other peaks are visible by GLC, and the NMR spectrum is consistent with the structure. [Mohammed & Kosower J Am Chem Soc 93 1709 1971, Beilstein 5 IV 809.] IRRITANT and strongly LACHRYMATORY.

不和合性

May form explosive mixture with air. Contact with water forms hydrogen chloride fumes. Strong oxidizers may cause fire and explosions. Unstabilized benzyl chloride undergoes polymerization with copper, aluminum, iron, zinc, magnesium, tin, and other common metals except lead and nickel, with the liberation of heat and hydrogen chloride gas. May accumulate static electrical charges, and may cause ignition of its vapors. Attacks some plastics and rubber. Thermal decomposition and polymerization reactions are inhibited, to a limited extent, by addition of triethylamine, propylene oxide, or sodium carbonate.

廃棄物の処理

Incineration @ 816 C for 0.5 second minimum for primary combustion and 1204 C for 12.0 second for secondary combustion. Elemental chlorine formation may be alleviated by injection of steam or methane into the combustion process.

塩化ベンジル 上流と下流の製品情報

原材料

準備製品


塩化ベンジル 生産企業

Global( 292)Suppliers
名前 電話番号 ファックス番号 電子メール 国籍 製品カタログ 優位度
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24191 60
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1861 55
Hebei Chisure Biotechnology Co., Ltd.
+8613292890173
0311 66567340 luna@speedgainpharma.com CHINA 1017 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30001 58
Hebei Ruishun Trade Co.,LTD
17052563120
Mike@rsbiology.com CHINA 302 58
Hebei Huanhao Biotechnology Co., Ltd.
86-0311-83975816 whatsapp +8618034554576
86-0311-83975816 grace@hbhuanhao.com CHINA 699 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23980 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58

100-44-7(塩化ベンジル)キーワード:


  • 100-44-7
  • BENZYL CHLORIDE, 99%BENZYL CHLORIDE, 99%BENZYL CHLORIDE, 99%BENZYL CHLORIDE, 99%
  • ALPHA-CHLOROTOLUENE
  • AKOS BBS-00003953
  • (chloromethyl)-benzen
  • (Chloromethyl)benzene
  • (chloromethyl)-Benzene
  • 1-Chloromethylbenzene
  • 1-Chlorome-thylbenzene
  • ai3-15518
  • alpha-chloro-toluen
  • alpha-Chlortoluol
  • alpha-tolylchloride
  • Benzene, (chloromethyl)-
  • benzene,(chloromethyl)-
  • benzene,chloromethyl-
  • Benzile
  • Benzile(cloruro di)
  • benzile(clorurodi)
  • Benzylchlorid
  • benzylchloride(dot)
  • benzylchloride00
  • Benzyle
  • Benzyle(chlorure de)
  • benzyle(chlorurede)
  • benzyle(chlorurede)(french)
  • C6H5CH2Cl
  • chloromethylbenzene
  • chloromethyl-benzene
  • Chlorophenylmethane
  • Chlorure de benzyle
  • 塩化ベンジル
  • (クロロメチル)ベンゼン
  • ベンジルクロリド
  • 1-クロロメチルベンゼン
  • クロロメチルベンゼン
  • 1-(クロロメチル)ベンゼン
  • クロロ(フェニル)メタン
  • α-クロロトルエン
  • フェニルクロロメタン
  • ω-クロロトルエン
  • フェニル(クロロ)メタン
  • クロロフェニルメタン
  • 化ベンジル
  • 塩化ベンジル 塩化物
  • Α-クロロトルエン標準品
  • ベンジル=クロリド (別名 塩化ベンジル)
  • ベンジル=クロリド(別名塩化ベンジル)
  • Α‐クロロトルエン標準品
  • ベンジルクロリド 塩化ベンジル
  • ベンジルクロリド STANDARD
  • ベンジルクロリド Standard, 5.0 mg/mL in Acetonitrile
  • ベンジルクロリド, 0.2 mg/mL in MeOH
  • 有機合成化学
  • 保護 & 誘導体化試薬 (合成用)
  • 生化学
  • 糖鎖合成用反応剤
Copyright 2017 © ChemicalBook. All rights reserved